1-50 of 67
Keywords: Autophagy
Close
Sort by
Articles
Biosci Rep (2022) 42 (9): BSR20221789.
Published: 23 September 2022
..., we summarize diverse evidence that support the role of peptides in this endeavor. Of particular interest to the present review are antimicrobial peptides (AMP) and cell-penetrating peptides (CPP). Different experimental evidence indicates that AMP/CPP are able to regulate autophagy, which in turn...
Articles
Biosci Rep (2022) 42 (6): BSR-2017-1691_RET.
Published: 30 May 2022
... Attribution License 4.0 (CC BY) . autophagy curcumin Osteoarthritis This article is being retracted from Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader alerting the Editorial Board to several duplications...
Articles
Biosci Rep (2022) 42 (4): BSR20212584.
Published: 19 April 2022
... autophagy in neurons. However, the mechanisms underlying microwave-induced autophagy were still unclear. In the present study, we established neuronal damage models by exposing rat hippocampal neurons and rat adrenal pheochromocytoma (PC12) cell-derived neuron-like cells to 30 mW/cm 2 microwaves, which...
Articles
Articles
Biosci Rep (2021) 41 (10): BSR20211056.
Published: 06 October 2021
.../M phase in H1299 cells. Mitochondria-mediated apoptosis was induced in A549 cells but not in H1299 cells after treatment with digoxin. Moreover, digoxin inhibited the migration, invasion, adhesion and epithelial–mesenchymal transition of A549 and H1299 cells. Autophagy was induced in both cell lines...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (8): BSR20211098.
Published: 20 August 2021
...Samuel Chuah; Valerie Chew Uveal Melanoma (UM) is a rare cancer deriving from melanocytes within the uvea. It has a high rate of metastasis, especially to the liver, and a poor prognosis thereafter. Autophagy, an intracellular programmed digestive process, has been associated with the development...
Articles
Articles
Articles
Biosci Rep (2021) 41 (5): BSR-20160523_RET.
Published: 14 May 2021
... duplicated within the Bioscience Reports article, in Figures 2F and 4B. This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. autophagy CRISPR/Caspase-9 glioma methylation TET1 © 2021 The Author(s). 2021 This is an open access...
Articles
Articles
Articles
Articles
Biosci Rep (2021) 41 (3): BSR20203812.
Published: 19 March 2021
...Zhuotao Zheng; Lingyue Zhang; Zewei Tu; Yan Deng; Xiaolong Yin Autophagy is involved in cancer initiation and progression but its role in uveal melanoma (UM) was rarely investigated. Herein, we built an autophagy-related gene (ARG) risk model of UM patients by univariate Cox regression and least...
Articles
Articles
Articles
Biosci Rep (2020) 40 (11): BSR20200661.
Published: 19 November 2020
... that Sop significantly mitigated TAC-induced heart dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis. Mechanistically, Sop treatment induced a remarkable activation of AMPK/mTORC1-autophagy cascade following sustained hypertrophic stimulation. Importantly, the protective effect of Sop was largely...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (9): BSR20201918.
Published: 28 September 2020
... could inhibit proliferation, induce G 2 /M cell cycle arrest and apoptosis, and could inhibit autophagy of acute leukemia cell lines in vitro . Thus, our findings suggest that SOV could effectively suppress the growth of acute leukemia HL60 cells and HL60/A cells through the regulations of proliferation...
Articles
Articles
Articles
Biosci Rep (2020) 40 (7): BSR-20160523_EOC.
Published: 02 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . autophagy CRISPR/Caspase-9 glioma methylation TET1 The Editorial...
Articles
In Collection
Coronavirus
Biosci Rep (2020) 40 (4): BSR20200905.
Published: 28 April 2020
...Anthony O. Fedele; Christopher G. Proud Autophagy is dependent upon lysosomes, which fuse with the autophagosome to complete the autophagic process and whose acidic interior permits the activity of their intraluminal degradative enzymes. Chloroquine (CQ) and bafilomycin A1 (BafA) each cause...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (4): BSR20193006.
Published: 31 March 2020
...Xiaomin Liu; Xiaowen Zhao; Rong Cheng; Yusen Huang Purpose: Autophagic dysfunction and abnormal oxidative stress are associated with cataract. The purpose of the present study was to investigate the changes of cellular autophagy and oxidative stress and their association in lens epithelial cells...
Includes: Supplementary data
Articles
Articles
Articles
Biosci Rep (2019) 39 (12): BSR20191041.
Published: 20 December 2019
... of mTORC. In addition, PD-L1 promotes the autophagy of ovarian cancer cells by up-regulating the expression of BECN1, a crucial molecule involved in the regulation of autophagy. In conclusion, PD-L1 may provide a target for the development of a novel strategy for the treatment of ovarian cancer. 16 04...
Articles
Articles
Biosci Rep (2019) 39 (12): BSR20191860.
Published: 04 December 2019
... II and p-AMPK expression. It was also found that CRA blunted cardiomyocyte hypertrophy and promoted autophagy in Angiotensin II (Ang II)-treated H9c2 cells. Moreover, to further verify whether CRA inhibits cardiac hypertrophy by the activation of autophagy, blockade of autophagy was achieved by CQ...
Includes: Supplementary data
Articles
Articles
Articles
Biosci Rep (2019) 39 (8): BSR20170770.
Published: 23 August 2019
...Jie Liu; Zhiyuan Chen; Jia Guo; Lei Wang; Xiuheng Liu Prostate cancer (PCa), the second most mortal cancer from developed countries, presents a high level of chemoresistance. There is emerging evidence underscores the critical role of autophagy in the onset, progression, and chemoresistance of PCa...
Articles
Biosci Rep (2019) 39 (8): BSR20190578.
Published: 07 August 2019
... the cells were treated with 9 mM 4-PBA and/or CHOP-siRNA4, the apoptosis rate, ROS level, lysosome activity and expression of PARP, Caspase-12, Caspase-3, LC3, Beclin-1 and CHOP were significantly reduced. Conclusions: Autophagy reaction mediated by endoplasmic reticulum stress plays important rale...
Articles
Biosci Rep (2019) 39 (8): BSR20190788.
Published: 02 August 2019
... in a variety of CVDs through post-transcriptional regulation of target gene proteins. Among them, microRNA-30 (miR-30) is one of the most abundant miRNAs in the heart. In recent years, the study found that the miR-30 family can participate in VR through a variety of mechanisms, including autophagy, apoptosis...
Articles
Articles
Biosci Rep (2019) 39 (7): BSR20190094.
Published: 23 July 2019
... (PRA) requires more attention. Hence, the current study aimed to examine whether mifepristone, a PRA, influences the autophagy and apoptosis of uterine leiomyoma cells. Primary uterine leiomyoma cells were collected from 36 patients diagnosed with uterine leiomyoma to establish PR-M-positive (PR-M...
Articles
Biosci Rep (2019) 39 (7): BSR20190035.
Published: 23 July 2019
... that SMG damage and repair often occur with autophagy in the rat. However, no studies reported whether secretory inhibition and structural changes of SMG after BTXA injection is related with autophagy. The present study was carried out to explore the association between BTXA injection and autophagy in rat...
Articles
Articles
Articles
Biosci Rep (2019) 39 (6): BSR20190502.
Published: 07 June 2019
... concentrations of EECR. Cell proliferation was examined using Cell Counting Kit-8 (CCK-8) and colony formation assays. Cell apoptosis and cell cycle were detected by flow cytometry. Apoptosis- and autophagy-related protein expression was detected by Western blot. EECR inhibits the proliferation of TNBC cells...
Articles
Articles
Biosci Rep (2019) 39 (4): BSR20190163.
Published: 17 April 2019
... to investigate AF cell senescence under mechanical tension and the potential role of autophagy. Methods: Rat AF cells were cultured and experienced different magnitudes (5% elongation and 20% elongation) of mechanical tension for 12 days. Control AF cells were kept static. Cell proliferation, telomerase activity...
Articles
Biosci Rep (2019) 39 (2): BSR20181345.
Published: 19 February 2019
... for their ability to induce the degradation of mutp53 through the activation of autophagy. Here, we investigated the correlation between autophagy and mutp53 degradation induced by suberoylanilide hydroxamic acid (SAHA), an FDA-approved histone deacetylase inhibitor. In the human cancer lines MDA-MB-231 (mutp53...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (1): BSR20181707.
Published: 15 January 2019
... of chamaejasmine is newly discovered from Stellera chamaejasmine L. Our study focuses on investigating the effect of chamaejasmine on the cellular apoptosis, proliferation, autophagy, and the underlying mechanisms in MG-63. Methods: Our study investigated the concentration of chamaejasmine in MG-63 cells by MTT...
Articles
Biosci Rep (2019) 39 (1): BSR20181156.
Published: 03 January 2019
...Ruben Adrian Grosso; Paula Virginia Subirada Caldarone; María Cecilia Sánchez; Gustavo Alberto Chiabrando; María Isabel Colombo; Claudio Marcelo Fader Hemin is an erythropoietic inductor capable of inducing autophagy in erythroid-like cell lines. Low-density lipoprotein receptor-related protein 1...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (6): BSR20181822.
Published: 30 November 2018
...Xiaokun Lin; Lei Han; Jialei Weng; Kelai Wang; Tongke Chen Objective To investigate the effect of Rapamycin on proliferation and autophagy in human neuroblastoma (NB) cell lines and to elucidate the possible mechanism. Methods NB cells were treated with different concentrations of Rapamycin. Cell...
Articles
Biosci Rep (2018) 38 (6): BSR20180876.
Published: 21 November 2018
... an average, and experiments were repeated independently at least three times. Acute renal injury Apoptosis Autophagy Contrast media mitochondrial injury Oxidative stress Contrast medium is used widely in many diagnostic and interventional procedures, and is a necessary component in modern...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (5): BSR20180516.
Published: 23 October 2018
...Qingqing Yin; Wei Feng; Xianjuan Shen; Shaoqing Ju Autophagy is an important process in endogenous substrate degradation by lysosomes within cells, with a degree of evolutionary conservation. Like apoptosis and cell senescence, cell autophagy is a very important biological phenomenon involving...
Articles
Biosci Rep (2018) 38 (4): BSR20170982.
Published: 18 July 2018
... can inhibit cardiac hypertrophy and block the development of heart failure by promoting autophagy. However, other investigators have demonstrated that overactive and dysregulated autophagy may also contribute to the onset and exacerbation of heart failure. Thus, a major goal of the present...
Articles
Articles
Biosci Rep (2018) 38 (4): BSR20171691.
Published: 03 July 2018
...Guowang Zhang; Jiaqing Cao; Erzhu Yang; Bo Liang; Jianing Ding; Jiaming Liang; Jianguang Xu Reduced autophagy has been implied in chondrocyte death and osteoarthritis. Curcumin (Cur) owns therapeutic effect against osteoarthritis (OA) and enhances autophagy in various tumor cells. Whether...
Articles
Biosci Rep (2018) 38 (2): BSR20171669.
Published: 20 April 2018
...). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cancer autophagy Leucin Rich Repeat Kinase 2 (LRRK2) mammalian Target Of Rapamycin (mTOR) Parkinson...
Includes: Supplementary data