... was decreased in the liver of DIO mice, and the reduction was blocked by treatment of the DIO mice with berberine (BBR). The mechanism of MECR protein regulation was investigated with a focus on ATP. The protein was decreased in the cell lysate and DIO liver by an increase in ATP levels. The ATP protein...

... of Berberine (BBR) on GDM and the possible mechanisms. The expressions and methylated states of HIF3A in pregnant women with GDM were compared with that in healthy controls. The IR cell models of 3T3-L1 adipocytes was constructed by 1 μmol/l dexamethasone (Dex) and 1 μmol/l insulin (Ins). To evaluate...

...Qiao Li; Ting Zhou; Chang Liu; Xiao-Yu Wang; Ji-Quan Zhang; Fei Wu; Ge Lin; Yue-Ming Ma; Bing-Liang Ma Berberine is a natural alkaloid that has antineoplastic effects. However, in hepatoma cells like HepG2, the expressions of uptake transporters are minimal but efflux transporters are relatively...

...Lei Li; Xiao Li; Xin Huang; Weilai Jiang; Letian Liu; Chunning Hou; Yanqing Yang; Lei Zhang; Xiaodan Zhang; Longwei Ye; Jie Yuan; Guolin Li; Haiming Sun; Limin Mao We introduced polyethyleneimine (PEI)-cholesterol (PC) as a nanocarrier incorporating berberine (BER) and miR-122 for the treatment...