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Keywords: Cancer
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Articles
Biosci Rep (2021) 41 (2): BSR20204043.
Published: 26 February 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cancer meta-analysis miR-142 prognosis Globally, tumors have become a major...
Articles
Biosci Rep (2021) 41 (2): BSR20193877.
Published: 03 February 2021
... cancer. Materials and methods: The data used in this research were collected from Google Scholar, Web of Science, CNKI, and Wan Fang Data databases. The final retrieval ended on 22 February 2019. The strength of correlation was assessed using odds ratios and 95% confidence intervals. Based on the...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20203995.
Published: 14 January 2021
...Weiwei Chen; Yuting Li; Liliangzi Guo; Chenxing Zhang; Shaohui Tang Background: Several studies have assessed the relationship between long non-coding RNA five prime to Xist (FTX) expression, clinicopathological features, and survival outcomes in patients with cancer with conflicting results. This...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20203559.
Published: 07 January 2021
...Mengqiu Xiong; Ping Wang; Bei Pan; Junjie Nie; Shukui Wang; Bangshun He MicroRNA-196a (miR-196a) was previously reported to be up-regulated in cancers, and it has the diagnostic and prognostic values in cancers. Whereas, the conclusion was still unclear according to the published data. To assess...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20203459.
Published: 07 January 2021
...Xiao-Jing Qin; Xu Lin; Gang Xue; Hui-Li Fan; Hao-Yu Wang; Jing-Fang Wu; Da Pei Background: In recent years, the annual incidence of thyroid cancer (TC) has increased, with papillary thyroid cancer (PTC) identified as the most commonwinwordpathological type accounting for approximately 80% of all...
Articles
Biosci Rep (2020) 40 (11): BSR20201820.
Published: 17 November 2020
...Bo Ma; Hui Li; Jia Qiao; Tao Meng; Riyue Yu Background: Head and neck squamous cell carcinoma (HNSCC) is recognised as an immune active cancer, but little is known about the role of microRNAs (miRNAs) in it. In the present study, we aim to determine a prognostic and immune-related miRNAs signature...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (11): BSR20202962.
Published: 13 November 2020
...Zhiding Wang; Mengzhen Wang; Jinghong Chen; Linlin Zhang; Li Zhang; Li Yu Cancer immunotherapy has recently undergone rapid development into a validated therapy for clinical use. The adoptive transfer of engineered autologous T cells, such as chimeric antigen receptor (CAR) T cells, has been...
Articles
Biosci Rep (2020) 40 (10): BSR20192051.
Published: 23 October 2020
...Abdolkarim Moazeni-Roodi; Sahel Sarabandi; Shima Karami; Mohammad Hashemi; Saeid Ghavami Fibroblast growth factor receptor 4 (FGFR4) is a cell surface receptor tyrosine kinases (RTKs) for FGFs. Several studies have focused on the association between FGFR4 polymorphisms and cancer development. This...
Articles
Biosci Rep (2020) 40 (9): BSR20202520.
Published: 02 September 2020
...Xiaoqi Yang; Haoran Liu; Tao Ye; Zhangqun Ye Background: Previously published studies have indicated that lymphoid enhancer-binding factor 1 (LEF1) expression could be recognized as a valuable biomarker to evaluate clinical outcome for various types of malignant cancer, but the results remained...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR20194468.
Published: 17 July 2020
...Shi Xu Fang; Cheng Chen; Qiang Guo; Xi Xian Ke; Hong Ling Lu; Gang Xu Background: SNHG15 has been reported to be aberrantly expressed in various tumor tissues and could serve as a promising prognostic cancer biomarker. Previous studies on SNHG15 yielded inconsistent results with insufficient...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR20191825.
Published: 09 July 2020
...Guang-Hui Qi; Chun-Hui Wang; Hong-Ge Zhang; Jian-Guo Yu; Fei Ding; Zhi-Chao Song; Qing-Hua Xia There is still no conclusion on the potential effect of the rs2295080 and rs2536 polymorphisms of mTOR (mammalian target of rapamycin) gene on different cancers. Herein, we performed a comprehensive...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (6): BSR20192410.
Published: 26 June 2020
...Li-Fang Wu; Gui-Ping Xu; Qing Zhao; Ding Wang; Li-Jing Zhou; Bin Sun; Wei-Xian Chen Background: The evidence for an association between the adiponectin gene (ADIPOQ) polymorphism rs182052 and cancer risk is inconsistent. We performed a meta-analysis to obtain more precise conclusions. Methods: The...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (6): BSR20200970.
Published: 08 June 2020
...Zohreh S. Miripour; Parisa Aghaee; Fereshteh Abbasvandi; Parisa Hoseinpour; Mohammad Parniani; Mohammad Abdolahad Lipid synthesis is the recently found metabolism of cancer cells after their metastasis to lymph nodes (LNs). Carbonic acid is the main byproduct of the lipid metabolism in such cells...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (5): BSR20192320.
Published: 28 May 2020
...Jingdong Li; Yaxuan Wang; Xueliang Chang; Zhenwei Han Purpose: To provide a comprehensive account of the association of five Lymphotoxin-α ( LTA ) gene polymorphisms (rs1041981, rs2229094, rs2239704, rs746868, rs909253) with susceptibility to cancer. Methods: A literature search for eligible...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (2): BSR20194335.
Published: 28 February 2020
...Dan-dan Hu; Hai-ling Chen; Li-ming Lou; Hong Zhang; Guo-liang Yang The processes that lead to lung adenocarcinoma (LUAD) metastasis are poorly characterized. Spindle and kinetochore associated complex subunit 3 (SKA3) plays a key role in cervical cancer development, but its contribution to LUAD is...
Articles
Biosci Rep (2020) 40 (2): BSR20193524.
Published: 07 February 2020
...Yuqin Yu; Dapeng Li; Ji’an Duan; Hongshuang Xu; Li Li; Dengwu Tan; Hong Yan Background: Oxycodone is an opioid medication used for the treatment of pain in cancer patients. However, little is known on the direct effects of oxycodone on cancer cells. Aim: To determine the effects and mechanisms of...
Articles
Biosci Rep (2019) 39 (12): BSR20190866.
Published: 17 December 2019
...Guowen Ding; Yu Chen; Huiwen Pan; Hao Qiu; Weifeng Tang; Shuchen Chen Background: Previous case–control studies have suggested that apurinic/apyrimidinic endonuclease 1 ( APE1 ) rs1760944 T>G polymorphism may be associated with cancer risk. Here, we carried out an updated meta-analysis to focus...
Articles
Biosci Rep (2019) 39 (12): BSR20192452.
Published: 04 December 2019
... clinical cancer. Methods We conducted a group of overall and subgroup pooling analyses after retrieving the data from four databases (updated till September 2019). The P -value of association, OR (odds ratios), and 95% CI (confidence interval) were calculated. Results We selected a total of 71 eligible...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (10): BSR20192274.
Published: 18 October 2019
...Caizhi Chen; Long Shu; Wen Zou Cancer incidence rate has increased so much that it is the second leading cause of deaths worldwide after cardiovascular diseases. Sensitive and specific biomarkers are needed for an early diagnosis of cancer and in-time treatment. Recent studies have found that long...
Articles
Biosci Rep (2019) 39 (10): BSR20190608.
Published: 11 October 2019
...Jing Ye; Haiyan Sun; Zhengquan Feng; Qiqin Zhang; Yongliang Xia; Yunxi Ji; Qiqing Zhang Background: Dysregulated expression of long non-coding RNA gastric carcinoma high expressed transcript 1 (lncRNA GHET1) has been observed in several cancers, however, definite conclusion on the prognostic value...
Articles
Biosci Rep (2019) 39 (9): BSR20190989.
Published: 20 September 2019
... malignancies compared with the normal population. In the present study, we aimed to identify, through in silico analysis, miRNAs and their target genes related to the three most frequent types of cancer in individuals with SCI. In a previous study, we reported a pattern of expression of miRNAs in 17 sedentary...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (8): BSR20190590.
Published: 28 August 2019
...Jiamin Zhu; Shusen Chen; Baixia Yang; Weidong Mao; Xi Yang; Jing Cai Radiotherapy is one of the main modalities of cancer treatment. However, tumor recurrence following radiotherapy occurs in many cancer patients. A key to solving this problem is the optimization of radiosensitivity. In recent...
Articles
Biosci Rep (2019) 39 (8): BSR20190741.
Published: 23 August 2019
... rs2682818 and overall cancers. Crude odds ratios (ORs) and 95% confidence intervals (CIs) analyzed by Z -test were employed to estimate the potential interrelation in five genetic models. We also prospected how the rs2682818 affects the second structure of miR-618. Finally, 10 independent studies meet the...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20182240.
Published: 28 June 2019
... LEPR rs1137101 variants with susceptibility of cancer, however, the observed results were controversial. We searched literature on the relationship of LEPR rs1137101 G>A polymorphism with cancer risk by using PubMed and Embase databases, covering all publications up to 14 October 2018. In total, 44...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20191298.
Published: 28 June 2019
...Xiaoxia He; Peng Wang; Ying Li; Na Shen Rs189037 (G>A) is an important functional variant with ataxia telangiectasia mutated ( ATM ) gene, which might affect ATM ’s expression involvement in several human cancers. Increasing evidence reveals that smoking-related cancers have distinct molecular...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (5): BSR20190754.
Published: 31 May 2019
... 28 04 2019 01 05 2019 10 05 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarkers cancer FEZF1-AS1...
Articles
Biosci Rep (2019) 39 (5): BSR20181785.
Published: 24 May 2019
... (ERCC4) gene and cancer susceptibility has been widely investigated. However, results thus far have remained controversial. A meta-analysis was performed to identify the impact of this polymorphism on cancer susceptibility. PubMed, Embase and Science-Web databases were searched systematically up to May...
Articles
Biosci Rep (2019) 39 (5): BSR20182370.
Published: 14 May 2019
...Yizhong Peng; Donghua Huang; Kaige Ma; Xiangyu Deng; Zengwu Shao MiR-19a was aberrantly expressed in various types of cancers and was observed to be potentially associated with the prognosis of cancer patients. The present analysis aims to elucidate its precise predictive value in various human...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (5): BSR20190456.
Published: 14 May 2019
...Songsong Teng; Chunhui Ma; Yinxian Yu; Chengqing Yi Ten-eleven translocation (TET) proteins are abnormally expressed in various cancers. Osteosarcoma cells were treated with hydroxyurea to investigate the expression pattern of TET proteins in these cells. The expression of TET1 was increased in...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (5): BSR20181991.
Published: 10 May 2019
...You Jiang; Jun Lu; Yue-E Wu; Xin Zhao; Liang Li Human leucocyte antigen-G (HLA-G) plays an important role in the progression of human cancers. A growing number of published studies have investigated the correlation between the HLA-G 3′ untranslated region (3′UTR) 14-bp insertion/deletion ( Ins/Del...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (4): BSR20180995.
Published: 26 April 2019
...Congmin Liu; Jing Jin; Jin Shi; Liqun Wang; Zhaoyu Gao; Tiantian Guo; Yutong He Background: Urothelial carcinoma associated 1 (UCA1), a novel long noncoding RNA (lncRNA) which is first discovered in 2006 in human bladder cancer and has become a hot spot in recent years. UCA1 has been demonstrated...
Articles
Biosci Rep (2019) 39 (4): BSR20181709.
Published: 09 April 2019
...-inflammatory conditions, eventually promoting the onset of human malignancies. In this review, we describe the structures and functions of the most well-defined NLR proteins and highlight their association and biological impact on a diverse number of cancers. Correspondence: Fernando J. Velloso...
Articles
Biosci Rep (2019) 39 (4): BSR20181915.
Published: 02 April 2019
...Boyu Tan; Ning Ning Alcohol consumption has been established to be a major factor in the development and progress of cancer. Genetic polymorphisms of alcohol-metabolism genes result in differences between individuals in exposure to acetaldehyde, leading to possible carcinogenic effects. Arg47His...
Articles
Biosci Rep (2019) 39 (4): BSR20190232.
Published: 02 April 2019
... of LINC00599 on glioma cell migration and invasion remain unknown. In our results, we first observe the expression of LINC00599 in 31 types of human cancers including tumor tissues and corresponding normal tissues at The Cancer Genome Atlas (TCGA) database, and found that LINC00599 expression levels...
Includes: Supplementary data
Articles
Biosci Rep (2019) BSR20181627.
Published: 25 March 2019
...Wei Liu; Qin-Peng Wang; Jia Guo Background : Several studies demonstrated that long non-coding RNA differentiation antagonizing non-protein coding RNA (lncRNA DANCR) expression might have the potential capacity to predict the cancer prognosis, however, definite conclusion has not been obtained. The...
Articles
Biosci Rep (2019) 39 (3): BSR20181809.
Published: 19 March 2019
...Yan Chen; Xiaoxue Qi; Ce Bian; Chen Ling; Tao Yi; Xiyan Mu; Xia Zhao The role of forkhead box P3 (FOXP3) protein in tumorigenesis has long been controversial and existing data on the association between FOXP3 gene polymorphisms and cancer susceptibility were inconsistent. Here, we conducted a meta...
Articles
Biosci Rep (2019) 39 (3): BSR20181928.
Published: 15 March 2019
... miRNAs. This review summarizes the newest information about the biology of two, AP-2α and AP-2γ, TFs in the carcinogenesis process. We emphasize that these two proteins could have either oncogenic or suppressive characteristics depending on the type of cancer tissue or their interaction with specific...
Articles
Biosci Rep (2019) 39 (1): BSR20181661.
Published: 18 January 2019
... demonstrated to act by activation of sphingomyelin synthase in the plasma membrane (PM) and lowering of phosphatidylethanolamine (PE) and phosphatidylcholine (PC) and their carcinogenic signaling. We show here that Minerval also acts, selectively in cancer cell lines, as an ATP depleting uncoupler of...
Articles
Biosci Rep (2019) 39 (1): BSR20180653.
Published: 15 January 2019
...Zhanzhan Li; Yanyan Li; Jun Fu; Na Li; Liangfang Shen We conducted comprehensive analyses to assess the diagnostic ability of miRNA-451 in cancers. A systematic online search was conducted in PubMed, Web of Science, China’s national knowledge infrastructure, and VIP databases from inception to July...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (6): BSR20181452.
Published: 14 December 2018
...Jialin Meng; Shuo Wang; Meng Zhang; Song Fan; Li Zhang; Chaozhao Liang G4C14-A4T14 polymorphism of TP73 gene has been reported with a potential association in cancer risks through affected cell homeostasis; however the results were not consistent. We performed a comprehensive meta-analysis to...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (6): BSR20180702.
Published: 14 November 2018
...Hui-Xia Wei; Guo-Xiang Tian; Ju-Kun Song; Lian-Jie Yang; Yu-Pei Wang Epidemiological studies have demonstrated close associations between SET8 rs16917496 T/C polymorphism and cancer risk, but the results of published studies were not consistent. We therefore performed this meta-analysis to explore...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (5): BSR20180942.
Published: 15 October 2018
...Zhiguo Sheng; Meini Kang; Hao Wang In the present study, we aimed at determining the potential role of rs12917 polymorphism of the O -6-methylguanine-DNA methyltransferase ( MGMT ) gene in the occurrence of cancer. Based on the available data from the online database, we performed an updated meta...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (5): BSR20181095.
Published: 28 September 2018
...Renfu Lu; Junjian Chen; Lingwen Kong; Hao Zhu Background: There is a dispute on the prognostic value of long non-coding RNA regulator of reprogramming (lncRNA ROR) in cancers. The purpose of the present study was to evaluate the prognostic significance of lncRNA ROR expression in human cancers...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (5): BSR20181039.
Published: 19 September 2018
...Zhibing Li; Yijian Li; Qibai Wang LINC00675 has been suggested to be dysregulated in gastric cancer, colorectal cancer and pancreatic cancer. However, the expression status and biological function of LINC00675 in glioma were still unknown. Thus, we reported LINC00675 was overexpressed in glioma...
Articles
Biosci Rep (2018) 38 (5): BSR20180658.
Published: 05 September 2018
...Xing-yan Li; Chun-hua Liang; Ye-jing Yang; Lei Liu; Yong-jun Du; Hong-suo Liang; Lin Li; Bo Zhang; Jian-min Li; Jin-min Zhao The aim of the present study was to determine whether High mobility group box 1 (HMGB1) polymorphism was associated with cancer susceptibility. PubMed, Embase, and ISI Web of...
Articles
Biosci Rep (2018) 38 (4): BSR20180365.
Published: 31 July 2018
...Xin Huang; Weiyue Zhang; Zengwu Shao Several studies have suggested that long non-coding RNA (lncRNA) gene polymorphisms are associated with cancer risk. In the present study, we conducted a meta-analysis related to studies on the association between lncRNA single-nucleotide polymorphisms (SNPs...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (4): BSR20180273.
Published: 31 July 2018
...Ben-Gang Wang; Li-Yue Jiang; Qian Xu miRNA polymorphisms had potential to be biomarkers for cancer susceptibility and prognosis. The mature miRNA-let-7 family was considered as the most important miRNA for the cancer incidence and progression. Recently, the promising let-7 miRNAs were reported to...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (4): BSR20171287.
Published: 13 July 2018
...Gautam Sethi; Muthu K. Shanmugam; Frank Arfuso; Alan Prem Kumar Evolving strategies to counter cancer initiation and progression rely on the identification of novel therapeutic targets that exploit the aberrant genetic changes driving oncogenesis. Several chromatin associated enzymes have been...
Articles
Biosci Rep (2018) 38 (4): BSR20180704.
Published: 06 July 2018
... of cancers, including breast cancer. In the present study, we further evaluated the role of MIAT in breast cancer and investigated the consequences of its silencing on breast cancer response to chemotherapeutic agents. Expression levels of MIAT mRNA in breast cancer were determined using TissueScan...
Articles
Biosci Rep (2018) 38 (3): BSR20180072.
Published: 27 June 2018
...Jing Wen; Zhi Lv; Hanxi Ding; Xinxin Fang; Mingjun Sun Single nucleotide polymorphisms (SNPs) in miRNA biosynthesis genes DROSHA and DGCR8 were indicated to be correlated with cancer risk. We comprehensively reviewed and analyzed the effect of DROSHA and DGCR8 polymorphisms on cancer risk. Eligible...
Includes: Supplementary data