...Yang Zhang; Leyan Li; Yi Tu; Zongfeng Feng; Zhengrong Li; Yi Cao; Yong Li The combination of docetaxel, cisplatin, and S-1 (DCS) is a common chemotherapy regimen for patients with gastric cancer (GC). However, studies on long noncoding RNAs (lncRNAs) associated with the chemotherapeutic response...

... will continue to impose a huge socio-economic burden on society. Currently, the most widely used clinical treatment modality is cytotoxic chemotherapy using platinum drugs which is used to treat variety of cancers. Despite its clinical success, critical challenges like resistance, off-target side effects...

... and characterise ascites-derived cells from a CRC patient. The samples were prepared using mechanical and enzymatic dissociations, and obtained before and after a chemotherapy treatment. Unbiased clustering of 19,653 cells from four samples reveals 14 subclusters with unique transcriptomic patterns in four major...

... factor-β, and intercellular cell adhesion molecule-1, meanwhile LIPUS will decrease the expression of interleukin-6, tumor necrosis factor-α, and vascular cell adhesion molecule-1. LIPUS has potential to be a new adjuvant therapy method in clinic for ameliorating chemotherapy-induced myelosuppression...

... Attribution License 4.0 (CC BY) . chemotherapy Colon cancer Irinotecan PHY906 traditional Chinese Medicine Human colon cancer cell line SW480 was seeded in six-well plates (Corning, U.S.A.) at a density of 5 × 10 4 cells/well. The cells were cultured in Roswell Park Memorial Institute (RPMI...

...Tong Qin; Hongmian Zhao; Yunli Shao; Ning Hu; Jinlong Shi; Lin Fu; Yijie Zhang The purpose of the present study was to investigate whether expression levels of adenylate kinase 1 (AK1) were associated with prognosis of acute myeloid leukemia (AML) in patients treated with chemotherapy or allogeneic...

... and hypophysitis. Conclusions: ICI therapy was safer than chemotherapy, especially ICI monotherapy such as anti-PD-1 antibodies in NSCLC. Compared with standard treatments, ICI drugs increased the risk of organ-specific IRAEs, although the overall incidence remained low. © 2020 The Author(s). 2020...

... cancer cell line [ 13 ]. Figure 1 Structures of the polynuclear ruthenium organometallic compounds chemotherapy cytotoxicity nucleotide excision repairn ruthenium XPA XPC Correspondence: Steven M. Shell ( [email protected] ) * These authors contributed equally...

...Bin Ke; Xinlin Wu; Qiong Yang; Yuanyuan Huang; Fang Wang; Yuxin Gong; Junfang Liu; Lin Shi Traditional Chinese Medicine (TCM) has been recognized to be conducive to enhancing the efficiency and reducing the side effects in the whole course of cancer treatment. The mechanisms of TCM/chemotherapy...

...-related LncRNA and up-regulated in many cancers for tumor growth and metastasis, but its role in chemotherapy resistance is unclear. We here investigated the function of LINC00473 in colorectal cancer (CRC) in vitro and in vivo . The CRC tissues ( n =20) and relative normal tissues were collected...

... observations suggest that MIAT plays an important role in breast tumorigenesis. Strategies to decrease MIAT expression levels may improve sensitivity to therapy in breast cancer by enhancing the apoptotic responses to conventional chemotherapies. Correspondence: M. Mourtada-Maarabouni ( m.m.maarabouni...

...Na Li; Wei Zhang Recently, autophagy has been indicated to play an essential role in various biological events, such as the response of cervical cancer cells to chemotherapy. However, the exact signalling mechanism that regulates autophagy during chemotherapy remains unclear. In the present study...

...Christina Peters; Stuart Brown Over the past couple of decades, antibody–drug conjugates (ADCs) have revolutionized the field of cancer chemotherapy. Unlike conventional treatments that damage healthy tissues upon dose escalation, ADCs utilize monoclonal antibodies (mAbs) to specifically bind...

... to antimetabolite chemotherapy. 5 9 2014 29 10 2014 5 11 2014 21 11 2014 © 2014 The Author(s) 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC-BY) ( http://creativecommons.org/licenses/by/3.0/ ) which permits...

... Antimalarials chemotherapy free radicals lipid peroxidation malaria oxidants Bioscience Reports, Vol. 21, No. 3, June 2001 ( 2001) Antimalarial Drugs Exacerbate Rat Liver Microsomal Lipid Peroxidation in the Presence of Oxidants E. Olatunde Farombi,1,2 Stanley Adoro,1 and Samuel Uhunmwangho1 Receiûed...

... Gertrude B. Elion and published in Les Prix Nobel 1988, printed in Sweden by Norstedts Tryckeri, Stockholm, Sweden, 1989, republished here with the permission of the Nobel Foundation, the copyright holder. © 1989 Plenum Publishing Corporation 1989 purine antimetabolite chemotherapy anti...