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Keywords: Cisplatin
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Articles
Biosci Rep (2021) BSR20192007.
Published: 07 June 2021
...Ying Yang; Zhifang Yang; Ruili Zhang; Chunli Jia; Rui Mao; Sha Ya; Yuefen Zhang; Ge Wu; Yan na Sun; Xiao yan Jia; Ainiwaer Aimudula; Hua Zhang; Yongxing Bao MicroRNAs (miRNAs) play an important role in drug-resistance, and it’s reported that MiR-27a-3p regulated the sensitivity of cisplatin...
Articles
Biosci Rep (2020) 40 (8): BSR-20190362_COR.
Published: 07 August 2020
... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bladder cancer cisplatin ERK PD-L1 The authors of the original article “Cisplatin contributes to programmed death-ligand 1 expression in bladder cancer through...
Articles
Biosci Rep (2020) BSR20201302.
Published: 27 May 2020
...Shoukai Zong; Wei Dai; Wencheng Fang; Xiangting Guo; Kai Wang The Accepted Manuscript version of this article (published on 27 May 2020) was withdrawn on 12 June 2020 due to concerns over authorship. WITHDRAWN ARTICLE WITHDRAWN: SIK2 Promotes Cisplatin Resistance Induced by Aerobic Glycolysis...
Articles
Biosci Rep (2020) 40 (1): BSR20191538.
Published: 17 January 2020
...Yan Hao; Fan Guo; Zhuo Huang; Yuying Feng; Zijing Xia; Jing Liu; Lingzhi Li; Rongshuang Huang; Lin Lin; Liang Ma; Ping Fu Histone deacetylases 6 (HDAC6) has been reported to be involved in the pathogenesis of cisplatin-induced acute kidney injury (AKI). Selective inhibition of HDAC6 might...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (9): BSR20190362.
Published: 06 September 2019
... in advanced BC is ongoing. In the present study, we used Western blot and quantitative real-time PCR (qPCR) to define the expression level of PD-L1 after cisplatin treatment in BC-derived cell lines. The signal activation was also evaluated by Western blot in BC-derived cell lines. We found...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (8): BSR20170770.
Published: 23 August 2019
.... In the present study, we investigated the possible role of a novel autophagy regulator, activating molecule in beclin1-regulated autophagy1 (Ambra1), a novel ATG gene in the sensitivity or PCa cells to cisplatin. We explored the regulation by the Ambra1 manipulation on the induction of apoptosis and autophagy...
Articles
Biosci Rep (2019) 39 (7): BSR20190198.
Published: 10 July 2019
... compared with their matched normal osteoblast tissues. We also observed significant miR-221 up-regulation in the OS cell lines, MG-63, SaoS-2, and U2OS, when compared with the normal osteoblast cell line, HOb. Overexpression of miR-221 promoted OS cell invasion, migration, proliferation, and cisplatin...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (7): BSR20182101.
Published: 05 July 2019
...Jin-Tian Miao; Jian-Hua Gao; Yong-Qian Chen; Hong Chen; Hao-Yi Meng; Ge Lou This paper tried to explore ANRIL expression in ovarian cancer and how it affects cisplatin-sensitivity of ovarian cancer cells via regulation of let-7a/high-mobility group protein A2 (HMGA2) axis. qRT-PCR was used...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20190381.
Published: 04 June 2019
... and arrested cell cycle in G 1 phase, moreover, Cyclin A, D1 and C-myc all revealed down-regulation in both MGC-803 and NCI-N87 cells. CCNE1 expression was significantly increased at low and moderate concentrations of Cisplatin. Down-regulation of CCNE1 expression would remarkably promote cell apoptosis...
Articles
Biosci Rep (2019) 39 (4): BSR20190016.
Published: 16 April 2019
... ability of OV-90 and SK-OV-3 cells, while colony formation assay and apoptosis detection showed that CHTOP knockdown markedly sensitized OV-90 and SK-OV-3 cells to cisplatin treatment by inducing apoptosis. Additionally, CHTOP silence also remarkably weakened the stemness of OV-90 and SK-OV-3 through...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (3): BSR20181426.
Published: 19 March 2019
... 2019 07 03 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cisplatin survival tuberous sclerosis complex...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (4): BSR20180547.
Published: 29 August 2018
...Pengfei Jin; Yanjun Liu; Ruijuan Wang Cisplatin is the first-line treatment for ovarian cancer. However, the clinical outcome of cisplatin treatment in ovarian cancer is hindered by cancer resistance. Here we aim to explore the role and mechanism of miR-216a in the cisplatin resistance of ovarian...
Articles
Biosci Rep (2018) 38 (3): BSR20180375.
Published: 31 May 2018
... could up-regulate the expressions of its target genes BCL-2 and CCND1 to antagonize the effects of NEAT1 knockdown. Furthermore, overexpressed NEAT1 reduced the sensitivity of cisplatin (DDP) and inhibited DDP-induced apoptosis and cell cycle arrest via miR-34c . The results in vivo also confirmed...
Articles
Biosci Rep (2018) 38 (2): BSR20171313.
Published: 27 April 2018
...-ribose) polymerase-1 (PARP1) inhibitor, over renal dysfunction and fibrosis during recovery phase of cisplatin (CisPt)-induced acute kidney injury (AKI) in rats. Male Wistar rats were distributed in three groups ( n =8 each group): control, CisPt, and CisPt + 5-AIQ. Control and CisPt groups received...
Articles
Biosci Rep (2017) 37 (3): BSR20170122.
Published: 27 June 2017
... siRNA was associated with increased sensitivity of breast cancer cells to cisplatin. Reduced growth and increased apoptosis of MCF-7 cells were observed in the CXCR4 siRNA group than in the control siRNA group. Taken together, our results present the treatment potential of chitosan nanoparticle...
Articles
Biosci Rep (2017) 37 (2): BSR20160445.
Published: 27 March 2017
..., we investigated the regulation by cisplatin on protein kinase C β (PKC β), on B-cell lymphoma 2 (Bcl-2) and on apoptosis in cervical cancer Hela cells. And then we examined the regulation by cisplatin on autophagy and the role of autophagy on the chemotherapy in Hela cells. In addition...