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Keywords: DNA damage
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Articles

Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women

Open Access
Gadah Albasher, May Bin-Jumah, Saleh Alfarraj, Fatimah Al-Otibi, Nouf K. Al-Sultan, Saud Alarifi, Saad Alkahtani, Nahed S. Alharthi, Wedad S. Al-Qahtani
Journal: Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20191434.
https://doi.org/10.1042/BSR20191434
Published: 07 February 2020
...), progesterone, testosterone and androstenedione in women during the menstrual period. Further, to screen and compare the 5α-reductase activities through the expression of SRD5A1, SRD5A2 and AR gene and to determine the level of VEGF, VKOR and SAA gene expression and DNA damage. A total of 30 Saudi women aged...
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Articles

Light-exposure at night impairs mouse ovary development via cell apoptosis and DNA damage

Open Access
Yapeng Li, Shunfeng Cheng, Lan Li, Yong Zhao, Wei Shen, Xiaofeng Sun
Journal: Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20181464.
https://doi.org/10.1042/BSR20181464
Published: 02 May 2019
... the concentrations of LH (luteinizing hormone), FSH (follicle-stimulating hormone) and E2 (estradiol) were increased, but the concentration of PROG (progesterone) was decreased. Moreover, 24-h light exposure increased the expression of DNA damage and repair related genes, the number of TUNEL and RAD51 positive cells...
View articletitled, Light-exposure at night impairs mouse ovary development via cell apoptosis and DNA damage
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Articles

Coagulansin-A has beneficial effects on the development of bovine embryos in vitro via HSP70 induction

Open Access
Imran Khan, Kyeong-Lim Lee, Md. Fakruzzaman, Seok-Hwan Song, Ihsan-ul-Haq, Bushra Mirza, Chang Guo Yan, Il-Keun Kong
Journal: Bioscience Reports
Biosci Rep (2016) 36 (2): e00310.
https://doi.org/10.1042/BSR20150222
Published: 16 March 2016
...-PCR). Additionally, the terminal deoxynucleotidyl transferase dUTP nick-end labelling (TUNEL) assay confirmed that coagulansin-A treatment significantly improved the embryo quality and reduced bovine embryo DNA damage ( P <0.05). The present study provides new information regarding the mechanisms...
View articletitled, Coagulansin-A has beneficial effects on the development of bovine embryos in vitro via HSP70 induction
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