... (PARPi) and other emerging DNA repair inhibitors for synthetic lethality in cancer. ATM inhibitors ATR inhibitors DNA synthesis and repair PARP PARP inhibitors Synthetic lethality If DNA lesions caused by the aforementioned agents remain unrepaired, mutations may arise which...

... & O’Farrell [ 71 ] observed that the recombinant molecules frequently had crossover sites very close to the mTTF/mTerf5 binding sites. DNA synthesis and repair Drosophila melanogaster mitochondria nucleic acids The mitochondrial DNA (mtDNA) in flies and humans is highly conserved in terms...

... with Portland Press and the Biochemical Society under a transformative agreement with JISC. DNA synthesis and repair inhibitor multidrug resistance Correspondence: Neil M. Kad ( [email protected] ) 26 02 2022 27 04 2022 12 05 2022 12 05 2022 For single-molecule...

... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . DNA replication and recombination DNA synthesis and repair genome integrity mtDNA Mitochondria are highly specialised and dynamic organelles required for fundamental cellular processes including...

... 04 2020 05 05 2020 18 05 2020 © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . DNA synthesis and repair Fanconi...

... [ 28 , 29 ]. DNA synthesis and repair epigenetic regulation Hepatocellular carcinoma histone H3 inflammation tumorigenesis The well-established definition of an epigenetic modification is a ‘stably heritable phenotype resulting from changes in a chromosome without alterations...