...Xingfang Zhang; Yajun Qiao; Mengyuan Wang; Xinxin Liang; Ming Zhang; Cen Li; Jixian Cairang; Jianv Wang; Hongtao Bi; Tingting Gao Depression is one of the most common mental disorders that affects hundreds of millions of people worldwide and has claimed tens of thousands of lives. The causes...

...Wenbin Liu; Zhuochun Huang; Jie Xia; Zhiming Cui; Lingxia Li; Zhengtang Qi; Weina Liu Sleep disorder caused by abnormal circadian rhythm is one of the main symptoms and risk factors of depression. As a known hormone regulating circadian rhythms, melatonin (MT) is also namely N-acetyl-5...

...Yanxia Zhang; Jie Liu; Yanqing Liu; Wei Lu; Ailian Hou Objective: We investigated the relationship between salivary cortisol level and the prevalence of depression 585 police officers working at the Police Departments of Beijing. Method: Cross-sectional data were obtained from 585 Chinese police...

...Huanping Wang; Huizhen Chen; Yang Gao; Shengju Wang; Xian Wang; Xiaomei Tang; Wei Fang; Xiaoyan Shi; Jia Yao; Qiu Chen Objective: Depression is a common complication in Type 2 diabetes mellitus (T2DM); however, it has long been underrecognized and undertreated. In the present study, we aimed...

...Zhiwen Gu; Jiyang Pan; Liping Chen Depression is a potentially life-threatening mental disorder with unknown etiology. Several microRNAs (miRNAs) have been shown to play critical roles in the etiology of depression. Here, we aim to elucidate the anti-depressive behavior of miR-124 suppression...

... treatment for depression, whereas its pathogenesis still remained not fully understood. The present research was conducted to evaluate the anti-depressive effect of OFG in mice and explore its potential mechanism. The OFG and ketamine (KET) were intragastrically and intraperitoneally treated, respectively...

...Xun Wang; Bing Wang; Jianping Zhao; Caixing Liu; Xianpeng Qu; Yuhuan Li Major depressive disorder (MDD) is a common mood disorder, and the treatment of MDD requires a variety of biopsychosocial approaches. The role of Silent information regulator 1 (SIRT1) in the regulation of MDD has recently been...

... emotional behaviors, including anxiety, social interaction, and depression-like behavior. We previously found that rats bred to display high levels of anxiety- and depression-like behavior exhibit diminished DNA methylation in the amygdala. We also observed that depleting dietary methyl donor content...

...Zhi-da Wang; Yu-fei Xia; Yue Zhao; Li-ming Chen This meta-analysis was performed to evaluate the effect of cognitive behavioural therapy (CBT) in improving the depression symptoms of patients with diabetes. Literature search was conducted in PubMed and Embase up to October 2016 without the initial...