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Keywords: Factor XIa
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Scaffold stability and P14′ residue steric hindrance in the differential inhibition of FXIIa by Aedes aegypti trypsin inhibitor versus Infestin-4

Open Access
Varsha Ashok Walvekar, Karthik Ramesh, Muthu Kannan, R. Manjunatha Kini, J. Sivaraman, Yu Keung Mok
Journal: Bioscience Reports
Biosci Rep (2022) 42 (5): BSR20220421.
https://doi.org/10.1042/BSR20220421
Published: 16 May 2022
... inhibitor Factor XIa Infestin Kazal-type protease inhibitor Factor XIIa (FXIIa), also known as Hageman factor, is a serine protease that plays a pivotal role in the intrinsic pathway of the blood coagulation cascade. Studies have reported that zymogen FXII circulates in the blood and becomes auto...
View articletitled, Scaffold stability and P14′ residue steric hindrance in the differential inhibition of FXIIa by Aedes aegypti trypsin inhibitor versus Infestin-4
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Includes: Supplementary data