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Keywords: Gastric cancer
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Articles
Biosci Rep (2021) BSR20211885.
Published: 25 November 2021
...Jiazhuan Mei; Guiju Liu; Ruijun Li; Peng Xiao; Dan Yang; Hua Bai; Yibin Hao Cisplatin (DDP) resistance is a huge obstacle to gastric cancer (GC) treatment. Long non-coding RNAs (lncRNAs) have been manifested to exert pivotal functions in GC development. Herein, we aimed to explore the functional...
Articles
Biosci Rep (2021) 41 (10): BSR20211476.
Published: 04 October 2021
...Yaqin Wang; Wenchao Chen; Kun Li; Gang Wu; Wei Zhang; Peizhi Ma; Siqi Feng Purpose: The aim of the present study was to screen differential metabolites of gastric cancer (GC) and identify the key metabolic pathways of GC. Methods: GC ( n =28) and matched paracancerous (PC) tissues were collected...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (9): BSR-2017-0136_RET.
Published: 22 September 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gastric cancer miR-182-5p This article is being retracted from...
Articles
Biosci Rep (2021) 41 (8): BSR-2018-1175_RET.
Published: 06 August 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cell growth Gastric cancer Metastasis MicroRNA-27a Neoadjuvant...
Articles
Biosci Rep (2021) 41 (7): BSR20204177.
Published: 28 July 2021
...Zhiping Chen; Tianyu Zhong; Tao Li; Jinghua Zhong; Yang Tang; Zhanyu Liu; Baodian Ling; Lanfeng Wang The gastric cancer (GC) patients commonly have a poor prognosis due to its invasiveness and distant metastasis. Growing evidence proved that aberrant long non-coding RNAs (lncRNAs) expression...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR-2018-0617_COR.
Published: 01 July 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gastric cancer Inhibitory kappa B Kinases nuclear factor kappa B prognosis...
Articles
Biosci Rep (2021) 41 (7): BSR20210055.
Published: 28 June 2021
...Qing Wang; Jiahong Liang; Xianyu Hu; Songgang Gu; Qiaodong Xu; Jiang Yan Gastric cancer (GC) is a heavy health burden around the world, which is the fifth most frequent tumor and leads to the third most common cancer-related deaths. It is urgent to identify prognostic markers as the guideline...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (4): BSR20204359.
Published: 22 April 2021
...Ya-zhen Zhu; Yi Liu; Xi-wen Liao; Shan-shan Luo Objective: We aimed to explore the prognostic value of a disintegrin and metalloproteinase with thrombospondin motifs ( ADAMTS ) genes in gastric cancer (GC). Methods: The RNA-sequencing (RNA-seq) expression data for 351 GC patients and other relevant...
Articles
Biosci Rep (2021) 41 (4): BSR-20180277_EOC.
Published: 19 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AK096174 Gastric cancer Invasion Long noncoding RNA WD repeat-containing...
Articles
Biosci Rep (2021) 41 (4): BSR20203676.
Published: 14 April 2021
...Zhenchao Ma; Jianwei Xu; Lixin Ru; Weihua Zhu Purpose: Detecting and diagnosing gastric cancer (GC) during its early period remains greatly difficult. Our analysis was performed to detect core genes correlated with GC and explore their prognostic values. Methods: Microarray datasets from the Gene...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (4): BSR-20193515_EOC.
Published: 06 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . DOT1L EPZ5676 Gastric cancer Prognosis The Editorial Office has been...
Articles
Biosci Rep (2021) 41 (4): BSR-20180617_EOC.
Published: 06 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gastric cancer Gene Expression Omnibus Inhibitory κB Kinases nuclear...
Articles
Biosci Rep (2021) 41 (4): BSR-20140020_EOC.
Published: 06 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gastric cancer MET miR-34a PDGFR The Editorial Office has been made...
Articles
Biosci Rep (2021) 41 (3): BSR20204425.
Published: 26 March 2021
... receptor. IL-1R2 is abnormally expressed in many human inflammatory diseases and cancers, and has important clinical significance. The present study was designed to investigate IL-1R2 expression in human gastric cancer (GC) tissues and the associated clinical implications. Methods: Immunohistochemistry...
Articles
Biosci Rep (2021) 41 (2): BSR20203336.
Published: 26 February 2021
...Jie Yu; QianYun Zhang; MengChuan Wang; SiJia Liang; HongYun Huang; Lang Xie; ChunHui Cui; JinLong Yu Tumor mutation burden (TMB) was a promising marker for immunotherapy. We aimed to investigate the prognostic role of TMB and its relationship with immune cells infiltration in gastric cancer (GC...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (2): BSR-20180538_EOC.
Published: 16 February 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell proliferation gastric cancer Hsa_circ_0000673 Invasion miR-532-5p...
Articles
Biosci Rep (2021) 41 (1): BSR20200842.
Published: 27 January 2021
...Shuitu Feng; Guoqin Qiu; Lihong Yang; Lihua Feng; Xin Fan; Fang Ren; Kaida Huang; Yide Chen The curative effect for patients with advanced gastric cancer is still unsatisfactory. Proton pump inhibitors could be a promising treatment strategy that could sensitize gastric cancer cells to antitumor...
Articles
Biosci Rep (2021) 41 (1): BSR20202564.
Published: 08 January 2021
...Yali Wang; Kun Zheng; Xiuqiong Chen; Rui Chen; Yanmei Zou Background: The present study aimed to use bioinformatics tools to explore pivotal genes associated with the occurrence of gastric cancer (GC) and assess their prognostic significance, and link with clinicopathological parameters. We also...
Articles
Biosci Rep (2021) 41 (1): BSR20202203.
Published: 06 January 2021
...Yuzhi Wang; Yu Zou; Yi Zhang; Chengwen Li The immune system and the tumor interact closely during tumor development. Aberrantly expressed long non-coding RNAs (lncRNAs) may be potentially applied as diagnostic and prognostic markers for gastric cancer (GC). At present, the diagnosis and treatment...
Articles
Biosci Rep (2021) 41 (1): BSR20203461.
Published: 06 January 2021
...Guoxiang Rong; Yongping Zhu; Weifeng Tang; Hao Qiu; Sheng Zhang The relationship between rs3746444 T>C single-nucleotide polymorphism (SNP) in microRNA (mir)-499 and risk of gastric cancer (GC) has been widely investigated. However, the association was still unconfirmed. Here, we first recruited...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (11): BSR20200305.
Published: 24 November 2020
...Xiaoling Kong; Sheng Yang; Caiping Liu; Hanqing Tang; Yingan Chen; Xiaomei Zhang; Yun Zhou; Geyu Liang Objective: Gastric cancer is the most common gastrointestinal malignancy in China and results from a combination of genetic and environmental factors. The present study was conducted...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (9): BSR20202102.
Published: 24 September 2020
...Fei Bai; Ke Xiao Background: Gastric cancer (GC) is a complex multifactorial disease. Previous studies have revealed genetic variations associated with the risk of gastric cancer. The purpose of the present study was to determine the correlation between single-nucleotide polymorphisms (SNPs...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (8): BSR20201807.
Published: 18 August 2020
...Zhenhua Guan; Jing Chen; Xueliang Li; Na Dong Gastric cancer represents a malignant type of cancer worldwide. Tanshinone IIA (Tan IIA), a pharmacologically active component isolated from the rhizome of the Chinese herb Salvia miltiorrhiza Bunge (Danshen), has been reported to possess an anti-cancer...
Articles
Biosci Rep (2020) 40 (8): BSR20191687.
Published: 11 August 2020
...) HOTTIP and gastric cancer risk/prognosis. Methods: A total of five HOTTIP SNPs among 627 gastric cancer cases and 935 controls were tested by Kompetitive Allele Specific PCR (KASP) assay. The functional SNPs underwent eQTL analysis and the expression of HOTTIP was assessed by quantitative RT-PCR. Results...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR-20181175_EOC.
Published: 29 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cell growth Efficacy Gastric cancer Metastasis MicroRNA-27a Neoadjuvant...
Articles
Biosci Rep (2020) 40 (6): BSR-20193176_EOC.
Published: 26 June 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . microRNA-217 PTPN14 gastric cancer EMT The Editorial Office has been...
Articles
Biosci Rep (2020) 40 (6): BSR20201275.
Published: 23 June 2020
...Xinhui Fang; Yangqiu Bai; Lida Zhang; Songze Ding Background: Gastric cancer (GC) is a malignant tumor of the digestive tract. Hypoxia plays an important role in the development of cancer, including GC. The present study aimed to investigate the role of circular RNA SLAMF6 (circSLAMF6...
Articles
Biosci Rep (2020) 40 (6): BSR20201199.
Published: 19 June 2020
...Fengchang Huang; Jin Wang; Yi Xu; Yunfei Zhang; Ning Xu; Liang Yin Isoliquiritigenin (ISL), a natural product isolated from licorice root, exhibits anti-gastric cancer effects. However, applications of ISL are still limited in clinical practice due to its poor bioavailability. To discovery of more...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (6): BSR20193181.
Published: 15 June 2020
...Chen Zeng; Ran Yan; Guanghua Yang; Sen Xiang; Fuli Zhao Gastric cancer (GC) is the fifth most common cancer worldwide and one of the most aggressive cancers in China. Glypican 6 is highly expressed in gastric adenocarcinoma and may act as a diagnostic and prognostic marker; however, the functional...
Articles
Biosci Rep (2020) 40 (5): BSR20193308.
Published: 20 May 2020
...Ming Wu; Yadong Wang; Hang Liu; Jukun Song; Jie Ding The immune infiltration of patients with gastric cancer (GC) is closely associated with clinical prognosis. However, previous studies failed to explain the different subsets of immune cells involved in immune responses and diverse functions...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (5): BSR20192372.
Published: 20 May 2020
...Mengxue Sun; Jie Hua; Gaoshuang Liu; Peiyun Huang; Ningsheng Liu; Xiaopu He Objective: The present study is designed to evaluate the anti-tumor effects of myrrh on human gastric cancer both in vitro and in vivo . Methods: The gastric cancer cell proliferation was determined by MTT assay. Apoptosis...
Articles
Biosci Rep (2020) 40 (3): BSR20194342.
Published: 09 March 2020
...Shuai Wu; Jian Xie; Hao Shi; Zi-wei Wang Objective: Metastasis and chemoresistance indicate treatment fail and progresses in gastric cancer (GC) patients. However, the molecular mechanisms of chemoresistance and metastasis remain unclear in GC. Thus, identifying the biological indicators...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (2): BSR20200041.
Published: 28 February 2020
... 4.0 (CC BY) . gastric cancer miR-139-5p proliferation SLC39A7 Gastric cancer (GC) is one of the most common malignancies occurring in the digestive tract. Each year, more than 700,000 people die of GC worldwide and there are nearly 1 million new cases of GC. Furthermore, the relative...
Articles
Biosci Rep (2020) 40 (2): BSR20192712.
Published: 14 February 2020
...) and cancer progression. However, studies focusing on the roles of PFDN in gastric cancer (GC) remain limited. The present study aims to evaluate the prognostic values of PFDN in GC. Prognostic roles of PFDNs were analyzed via the Kaplan–Meier platform, followed by subset analysis within various clinical...
Articles
Biosci Rep (2020) 40 (1): BSR20193515.
Published: 31 January 2020
... the differences in DOT1L expression and its regulatory mechanism in gastric cancer (GC) and healthy samples. Methods : Immunohistochemistry was used to detect DOT1L levels in 101 cases of GC and marching adjacent normal tissues. DOT1L was inhibited by small interfering RNA (siRNA) and EPZ5676; a targeting drug...
Articles
Biosci Rep (2020) 40 (1): BSR20193176.
Published: 07 January 2020
...Gen Chen; Zhangshuo Yang; Maohui Feng; Zhiliang Wang Background: Gastric cancer (GC) is the one of most common malignancies and its mechanism of metastasis remains unclear. The study was designed to investigate the effects of microRNA-217 on epithelial-to-mesenchymal transition. Methods...
Articles
Biosci Rep (2019) 39 (12): BSR20192726.
Published: 24 December 2019
...Lihong Yang; Xiaojun Huang; Wei Wang; Tao Jiang; Feifei Ding X-linked ectodermal dysplasia receptor (XEDAR) has been widely studied in epidermal morphogenesis, but few studies have been conducted on tumorigenesis and development, including gastric cancer. In the present research, we aimed...
Articles
Biosci Rep (2019) 39 (11): BSR20190505.
Published: 15 November 2019
...Hongbing Zhai; Yanju Li Long non-coding RNA brain cytoplasmic RNA 1 (BCYRN1) has been found to play an important role in tumorigenesis of a variety of tumors including gastric cancer (GC). However, the prognostic significance and molecular mechanism of BCYRN1 was still unknown in GC. In the present...
Articles
Biosci Rep (2019) 39 (9): BSR20190654.
Published: 06 September 2019
...Lan Feng; Kai Cheng; Rongjia Zang; Qingdong Wang; Jianjie Wang MicroRNA plays an important role in gastric cancer (GC) development, while the function of miR-497-5p in this disease remains unknown. In the present study, we demonstrated miR-497-5p as a tumor suppressive microRNA in GC. miR-497-5p...
Articles
Biosci Rep (2019) 39 (9): BSR20181025.
Published: 03 September 2019
...Kangpeng Yan; Kun Wu; Chao Lin; Zhigang Jie Previous studies have identified the prostate stem cell antigen ( PSCA ) gene rs2294008 C > T and rs2976392 G > A polymorphisms to be associated with the risk of gastric cancer, the results of which are inconsistent. The present study aimed...
Articles
Biosci Rep (2019) 39 (7): BSR20181434.
Published: 23 July 2019
...Kun Wu; Jun Zou; Chao Lin; Zhi-Gang Jie Studies have highlighted the importance of microRNAs (miRs) in the development of various cancers, including gastric cancer (GC), a commonly occurring malignancy, accompanied by high recurrence and metastasis rate. The aim of the current study...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20190066.
Published: 28 June 2019
...Zhenglei Xu; Zhichao Yu; Qinghong Tan; Cheng Wei; Qi Tang; Lisheng Wang; Yingcai Hong MicroRNAs (miRNAs) are reported to play critical roles in various cancers. Recently, mounting miRNAs are found to exert oncogenic or tumor inhibitory role in gastric cancer (GC), however, their potential molecular...
Articles
Biosci Rep (2019) 39 (6): BSR20181900.
Published: 28 June 2019
...Min Liang; Zhaoyu Liu; Hai Lin; Boyun Shi; Ming Li; Ting Chen; Lingyu Qin; Qiuling Niu; Guifang Yu; Hui Jiang; Xinke Zhou Background/Aim: Gastric cancer is one of the most common malignant tumors, and its complex pathogenesis has not been fully elucidated. Circular RNAs (circRNAs) are involved...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20181258.
Published: 10 June 2019
...Junxia Gu; Xiaozhen Li; Hui Li; Zhe Jin; Jianjun Jin MicroRNAs (miRNAs) are increasingly recognized as important therapeutic targets in cancer. Here we aim to investigate the role of miR-198, a broad-spectrum tumor suppressor, in gastric cancer (GC). MiR-198 overexpression was achieved...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (5): BSR20181175.
Published: 21 May 2019
...Chunlei Xu; Hong Cheng; Na Li; Ning Zhou; Xushan Tang Objective: The aim of the present study is to investigate the relationship between microRNA-27a (miR-27a) and the efficacy of neoadjuvant chemotherapy in gastric cancer (GC) and its mechanism in the growth and metastasis of GC cells. Methods...
Articles
Biosci Rep (2019) 39 (5): BSR20190363.
Published: 21 May 2019
...Jian He; Jie Chen; Ben Ma; Li Jiang; Guangfa Zhao Recently, circRNAs have been found to play regulatory roles in cancer. In the present study, we aimed to investigate the characteristics and effect of circLMTK2, and its potential role as a novel biomarker in cases of gastric cancer (GC). About 111...
Articles
Biosci Rep (2019) 39 (5): BSR20190101.
Published: 17 May 2019
...Sifeng Hu; Fanmei Meng; Xiankun Yin; Changling Cao; Guangyong Zhang Ecto-5′-nucleotidase (NT5E) is a glycosylphosphatidylinositol anchored cell surface protein, and has been suggested to be dysregulated in most types of human cancer including gastric cancer. The aim of the present study...
Articles
Biosci Rep (2019) 39 (5): BSR20190357.
Published: 17 May 2019
...Zheng Wang; Xiaoli Tang; Xiaoqing Wu; Meiyuan Yang; Wei Wang; Liuhua Wang; Dong Tang; Daorong Wang Background: Gastric cancer is one of the most commonly diagnosed cancers each year, and it remains the third leading cause of cancer death in the world. The clinicopathologic characteristics differ...
Articles
Biosci Rep (2019) 39 (5): BSR20182321.
Published: 15 May 2019
...Hong-wei Cui; Wen-yan Han; Li-na Hou; Ling Yang; Xian Li; Xiu-lan Su Many gene expressions changed during the development of gastric cancer, and non-coding RNAs including microRNAs (miRNAs) have been found to regulate cancer progression by participating in the process of tumor cell growth...
Articles
Biosci Rep (2019) 39 (5): BSR20182044.
Published: 14 May 2019
... demonstrated an immune-modulatory capacity by Notch signaling inactivation to reverse Tregs–Th17 disequilibrium in chronic hepatitis C. Thus, the aim of current study was to assess the role of Notch signaling in modulation Tregs and Th17 cells function in gastric cancer (GC) patients. A total of 51 GC patients...