... and has not responded to the Journal's queries or the concerns raised. Several listed co-authors wish to retract the article and the Editorial Board agree with the Retraction. Case-control Gene polymorphism Hypospadias Risk TGFBR1 TGFBR2 © 2022 The Author(s). 2022 This is an open access...

... and medical records was performed. Results revealed that nephrosis 2 (NPHS2) gene polymorphism aggravated renal damage in three FSGS families with heterozygous COL4A3 mutation, leading to early renal failure in index patients. Our findings suggest that COL4A3 and NPHS2 may have a synergistic effect on renal...

... Newcastle–Ottawa Scale (NOS) ranging from a low of 0 to a high of 10 with the higher score representing higher quality. The cut-off values of NOS < or =5 suggested low-quality study while NOS >6 suggested high-quality study. Diabetic microvascular complications Gene polymorphism Interleukin...

...Heqing Lai; Guochao Xu; Haifeng Meng; Haiying Zhu Objective: To study the association between SP1 rs1353058818 and STAT3 rs1053004 gene polymorphisms and risk of human tongue squamous cell carcinoma (TSCC). Methods: Sanger sequencing was used to determine the genotypes of SP1 rs1353058818 and STAT3...

... BY) . CYP3A4 gene polymorphism Hardy-Weinberg knee osteoarthritis The genotype distribution of CYP3A4 rs4646437 were presented in the Table 2 . The GG, GA, and AA genotype were 303 (58.3%), 176 (33.8%), and 41 (7.9%) in the control group and were 246 (54.7%), 129 (28.7%), and 75 (16.7...

... nucleotide polymorphism (SNP) is more than 90% of human gene polymorphisms, which is the most common and stable gene variant in the human DNA strands [ 13 ]. The coding SNP consisted of synonymous coding SNP and non-synonymous coding SNP. Research has demonstrated that genetic factors contribute enormously...

...Dexi Jin; Min Zhang; Hongjun Hua Background: This research aimed to study the associations between XPD (G751A, rs13181), hOGG1 (C326G, rs1052133) and XRCC4 (G1394T, rs6869366) gene polymorphisms and the risk of colorectal cancer (CRC) in a Chinese Han population. Method: A total of 225 Chinese Han...

... was still significantly associated with KOA. There were no significant differences in allele frequency or genotypes frequency for erythrocyte sedimentation rate and C-reaction protein in OA patients ( P >0.05). ADAMTS14 gene polymorphism was associated with KOA, and the GG genotype increased the risk...

... is still unclear. It is known to all that CRC is a multifactorial and multigenic disease, and is influenced by environment conditions, diet habits, genetic mutations, and Escherichia coli infection [ 3 , 4 ]. With increasing numbers of studies, more gene polymorphisms were found to contribute to CRC [ 5...

...Ying-Bin Wang; Rong-Zhi Zhang; Sheng-Hui Huang; Shu-Bao Wang; Jian-Qin Xie The present study aimed to investigate the influence of UGT1A9 gene polymorphisms on the efficacy of propofol in patients undergoing the painless induced abortion method. A total of 156 women seeking voluntary pregnancy...

...-β (TGF-β) receptor type I and II ( TGFBR1 and TGFBR2 ) gene polymorphisms with the risk of hypospadias in a Chinese population. One hundred and sixty two patients suffering from hypospadias were enrolled as case group and 165 children who underwent circumcision were recruited as control group...

...Hong-Wei Yang; Ying-Xue Wang; Jie Bao; Shu-Hui Wang; Ping Lei; Zhao-Lin Sun The present study aims to explore the correlation of human leucocyte antigen ( HLA ) -DQ and tumour necrosis factor ( TNF ) -α gene polymorphisms with ocular myasthenia gravis (OMG) combined with thyroid-associated...