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Keywords: Glutamine metabolism
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Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (3): BSR20232035.
Published: 12 March 2024
... exerts an effect on EC via glutamine metabolism is unknown. In the present study, we found that P4 could inhibit glutamine metabolism in EC cells and down-regulate the expression of the glutamine transporter ASCT2. This regulation of ASCT2 affects the uptake of glutamine. Furthermore, the in vivo...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (3): BSR20212171.
Published: 16 March 2022
... attenuated the increase in the ROS levels and reduced ATP generation. These data suggest that ASCT2 mediates glutamine metabolism and maintains redox homeostasis in PC. To further investigate whether ASCT2 is involved in PC cell growth, we blocked ASCT2 activity with the ASCT2 inhibitor l -γ-glutamyl- p...
Includes: Supplementary data
