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Keywords: HeLa
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Articles

Elucidation of rutin’s role in inducing caspase-dependent apoptosis via HPV-E6 and E7 down-regulation in cervical cancer HeLa cells

Open Access
Pratibha Pandey, Fahad Khan, Mohd Farhan, Asif Jafri
Journal: Bioscience Reports
Biosci Rep (2021) 41 (6): BSR20210670.
https://doi.org/10.1042/BSR20210670
Published: 21 June 2021
...)-E6 and E7 oncoproteins in cervical cancer has not been elucidated yet. This research addresses the growth inhibitory efficacy of rutin against E6 and E7 oncoproteins in HeLa cells, which is known to inactivate several tumor suppressor proteins such as p53 and pRB. Rutin treatment exhibited reduced...
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Articles

UV-Induced Apoptosis in Resistant HeLa Cells

Available to Purchase
P. Kamarajan, Chuck C.-K. Chao
Journal: Bioscience Reports
Biosci Rep (2000) 20 (2): 99–108.
https://doi.org/10.1023/A:1005515400285
Published: 01 April 2000
... in HeLa cells and itsrole in acquired UV-resistance. The membrane receptor Fas was induced toassembly, and its immediate downstream target, caspase-8, was induced byUV in a dose- and time-dependent manner. Caspase-10, another possiblecandidate for forming the death-inducing signaling complex with Fas...
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