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Keywords: Infestin
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Scaffold stability and P14′ residue steric hindrance in the differential inhibition of FXIIa by Aedes aegypti trypsin inhibitor versus Infestin-4

Open Access
Varsha Ashok Walvekar, Karthik Ramesh, Muthu Kannan, R. Manjunatha Kini, J. Sivaraman, Yu Keung Mok
Journal: Bioscience Reports
Biosci Rep (2022) 42 (5): BSR20220421.
https://doi.org/10.1042/BSR20220421
Published: 16 May 2022
... sought to compare the inhibitory properties of two Kazal-type inhibitors, Infestin-4 (Inf4), a potent inhibitor of FXIIa, and Aedes aegypti trypsin inhibitor (AaTI), which does not inhibit FXIIa, to better understand Kazal-type protease specificity and determine the structural components responsible...
View articletitled, Scaffold stability and P14′ residue steric hindrance in the differential inhibition of FXIIa by Aedes aegypti trypsin inhibitor versus Infestin-4
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Includes: Supplementary data