... This article “XEDAR inhibits the proliferation and induces apoptosis of gastric cancer cells by regulating JNK signaling pathway” (DOI: 10.1042/BSR20192726 ) is being retracted from Bioscience Reports at the request of the authors, who state they have been unable to replicate the results...

... JNK signaling pathway This article is being retracted from Bioscience Reports following receipt of a notification from a reader, alerting the Editorial Office to Figure 3C pLKO.1 panel which seems to appear as Figure 4D 5-FU pLKO.1 panel from Xu et al, 2020 (DOI: 10.1111/jcmm.15070...

..., overexpression of XEDAR inhibited cell proliferation and induced apoptosis in BGC-823 cells. XEDAR moreover inhibited proliferation and induced apoptosis in gastric cancer cells by regulating the JNK signaling pathway. Collectively, the results of the present study suggested that XEDAR inhibits cell...

... and suppressed cell apoptosis, whereas DEPDC1 depletion inhibited cell proliferation and promoted cell apoptosis. Furthermore, DEPDC1 ablation suppressed tumorigenecity of HCC cells in murine xenograft models. Mechanistic studies uncovered that JNK signaling pathway mediated the promoting effects of DEPDC1...