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Keywords: Lung cancer
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Articles
Cindy Mendes, Isabel Lemos, Ana Hipólito, Bruna Abreu, Catarina Freitas-Dias, Filipa Martins, Rita F. Pires, Hélio Barros, Vasco D.B. Bonifácio, Luís G. Gonçalves, Jacinta Serpa
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (7): BSR20240752.
Published: 31 July 2024
...Cindy Mendes; Isabel Lemos; Ana Hipólito; Bruna Abreu; Catarina Freitas-Dias; Filipa Martins; Rita F. Pires; Hélio Barros; Vasco D.B. Bonifácio; Luís G. Gonçalves; Jacinta Serpa Lung cancer ranks as the predominant cause of cancer-related mortalities on a global scale. Despite progress...
Includes: Supplementary data
Articles
MiRNA-423 rs6505162 and miRNA-6811 rs2292879 SNP associated with lung cancer in Hainan, China
Open AccessJing Zhou, Chong Meng, Yixuan Li, Yihui Fu, Wenfang Long, Hairong Huang, Yunru Liu, Pengfei Lyu, Sha Xiao
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (9): BSR20231152.
Published: 22 September 2023
... was to examine the impact of eight single-nucleotide polymorphisms (SNPs) in miRNA on the susceptibility to lung cancer (LC) within the Chinese Southern population. Methods: The genotypes of these eight polymorphisms were determined in 132 LC patients and 214 cancer-free controls. Results: In overall analyses...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (9): BSR20230057.
Published: 11 September 2023
... promoted cancer cell migration in vitro and metastasis in vivo . The latest research from Sabine’s team has demonstrated that in H1299 lung cancer cells, the mechanism by which ITPKA promoted migration and invasion was predominantly depending on the ability of binding to F-actin, which will induce cancer...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (2): BSR20221659.
Published: 02 February 2023
...Bin Yi; Yuanda Cheng; Ruimin Chang; Wolong Zhou; Huili Tang; Yang Gao; Chunfang Zhang Background: The prognostic significance of tumor-associated macrophages (TAMs) in patients with lung cancer (LCa) remains controversial. We therefore conducted the present study to systematically evaluate the role...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20212416.
Published: 18 January 2022
... Computed tomography Ground-glass nodules Lung cancer Lung cancer is the second most common cancer and remains the leading cause of cancer deaths for both men and women, with an estimated 1.8 million deaths (18%) [ 1 ]. Lung adenocarcinoma is the most common subtype of non-small cell lung cancer...
Includes: Supplementary data
Articles
Microarray analysis of genes with differential expression of m6A methylation in lung cancer
Open Access
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (9): BSR20210523.
Published: 17 September 2021
...Shuo Wu; Xing Lv; Yan Zhang; Xi Xu; Feng Zhao; Yao Zhang; Lizhan Chen; Haifeng ou-Yang; Xinyu Ti Purpose: N6-methyladenosine (m6A) is among the most abundant mRNA modifications in eukaryote. The aim of the present study was to investigate function of m6A mRNA methylation in lung cancer...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (8): BSR20210866.
Published: 02 August 2021
...Peng Yan; Yiming Han; Anna Tong; Jie Liu; Xinyu Wang; Chuanyong Liu Background: Increased serum neuron-specific enolase (NSE) level was found in a substantial proportion (30–69%) of patients with non-small-cell lung cancer (NSCLC), but little was known about the clinical properties of NSE in NSCLC...
Articles
Prediction of prognosis of patients with lung cancer in combination with the immune score
Open Access
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (5): BSR20203431.
Published: 14 May 2021
...Ke Han; Kun Qian; Teng Zhao; Xing Sheng Liu; Yi Zhang Purpose: The host’s immune response to malignant tumor is fundamental to tumorigenesis and tumor development. The immune score is currently used to assess prognosis and to guide immunotherapy; however, its association with lung cancer prognosis...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (4): BSR-20150300_RET.
Published: 22 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . lung cancer miR-148b MutL homologue 1 (MLH1) radioresistance...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20204062.
Published: 12 February 2021
...Zhenjie Zhuang; Tong Lin; Lixia Luo; Weixin Zhou; Junmao Wen; Haifu Huang; Zhanhua Liu; Lizhu Lin Background . Aidi injection (ADI) is an effective Traditional Chinese medicine preparation widely used for lung cancer. However, the pharmacological mechanisms of ADI on lung cancer remain...
Includes: Supplementary data
Articles
Mohammed H. Hassan, Sawsan Abuhamdah, Mohamed Abdel-Bary, Mohammed Wahman, Tarek Hamdy Abd-Elhamid, Morris Beshay, Karam Mosallam, Bakheet E.M. Elsadek
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203097.
Published: 06 January 2021
... for tumor suppression or propagation. The present study aimed to validate the expression levels of survivin and fibulin-3 in benign and malignant respiratory diseases. This case–control study included 219 patients categorized into five groups. Group A included 63 patients with lung cancer, group B included...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20190701.
Published: 05 October 2020
...Peng Xie; Yesong Guo Lung cancer (LC) is characterized by high morbidity and mortality. Numerous long noncoding RNAs (lncRNAs) have been reported to be involved in the initiation and progression of human cancers, including LC. Long intergenic non-protein coding RNA 205 (LINC00205) is identified...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20202275.
Published: 29 September 2020
...Wen-Ping Zhang; Xiao-Feng He; Xiang-Hua Ye Background: Many studies have been performed to explore the combined effects of glutathione-S-transferase M1 ( GSTM1 ) present/null and cytochrome P4501A1 ( CYP1A1 ) MspI polymorphisms with lung cancer (LC) risk, but the results are contradictory. Two...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR-20190159_COR.
Published: 07 August 2020
... Figure 5 Isorhamnetin inhibits the activation of MMP-2 and MMP-9 in A549 cells ( A ) Effects of Isorhamnetin (0, 2.5, 5, and 10 μM) on the protein expression of E-cadherin, N-cadherin, vimentin, snail, and slug of A549 lung cancer cells. ( B ) Quantitative result of E-cadherin, N-cadherin...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR-20190159_EOC.
Published: 30 June 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Isorhamnetin Lung cancer Metastasis Epithelial-mesenchymal transition (EMT...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20201170.
Published: 23 June 2020
...Yongyong Wang; Xiaowu Fan; Xiaowei Wu A homogeneous polysaccharide (GLP), with an average molecular weight of 4.44 × 10 4 Da, was isolated and purified from the fruiting bodies of Ganoderma lucidum . In this work, we examined the antitumor activities of GLP using a mouse Lewis lung cancer (LLC...
Articles
Treatment- and immune-related adverse events of immune checkpoint inhibitors in advanced lung cancer
Open Access
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20192347.
Published: 07 May 2020
...Jun Shao; Chengdi Wang; Pengwei Ren; Yuting Jiang; Panwen Tian; Weimin Li Background: Immune checkpoint inhibitors (ICIs) emerged as the preferred therapy in advanced lung cancer, understanding the treatment- and immune-related adverse events of these drugs is of great significance for clinical...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20192761.
Published: 28 April 2020
... the expression of CD47 in lung cancer A549 cells via the next-generation sequencing, indicating that CD47 might be involved in H 2 -mediated lung cancer repression. Therefore, the present study aimed to explore the effects of CD47 on H 2 -induced lung cancer repression. Western blotting and real-time PCR (RT-PCR...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20194027.
Published: 23 April 2020
... and the Biochemical Society under a transformative agreement with JISC. colonic cancer glioma lung cancer metabolomics NMR spectroscopy renal cancer Correspondence: Jia V. Li ( [email protected] ) or Daqing Ma ( [email protected] ) Metabolic phenotyping is a powerful tool to profile...
Includes: Supplementary data
Articles
Evaluation of models for predicting the probability of malignancy in patients with pulmonary nodules
Open Access
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20193875.
Published: 28 February 2020
... in predicting the benign and malignant lung nodules, distinguishing between early and late lung cancers, and between adenocarcinoma and squamous cell carcinoma. In the present study, we compared four widely used and well-known mathematical prediction models. Materials and methods: We performed a retrospective...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20193075.
Published: 11 February 2020
... the expression patterns and prognostic values of individual ID family members in lung cancer, and the potential functional roles. The expression levels of ID family were assessed using the Oncomine online database and GEPIA database. Furthermore, the prognostic value of ID family members was evaluated using...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (9): BSR20190159.
Published: 20 September 2019
...Wei Luo; Qingbin Liu; Nan Jiang; Mingquan Li; Li Shi In the present study, we investigated the potential effects of Isorhamnetin on the growth and metastasis of A549 human lung cancer cells, as well as the underlying mechanism. Treatment with Isorhamnetin exhibited a dose- and time-dependent...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190634.
Published: 12 July 2019
... cancer were searched by miRNA microarray using a previously established brain metastatic lung cancer model. Twenty-five miRNAs were down-regulated in brain metastatic lung cancer cells. Among those, miR-193b-3p and -5p were chosen for further studies. Their function in metastatic potential...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20181936.
Published: 20 June 2019
...Chen Chen; Jing-Ni Liu; Jian-Qiang Zhao; Bao Zang Chronic inflammation plays an important role in lung carcinogenesis. Recently, several studies investigated the association of C-reactive protein (CRP) gene 1846C>T polymorphism and lung cancer (LC) risk, but with conflicting findings...
Articles
Baicalin suppresses lung cancer growth by targeting PDZ-binding kinase/T-LAK cell-originated protein kinase
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20181692.
Published: 09 April 2019
... studies showed that baicalin suppressed PBK/TOPK activity in JB6 Cl41 cells and H441 lung cancer cells. Moreover, knockdown of PBK/TOPK in H441 cells decreased their sensitivity to baicalin. In vivo study indicated that injection of baicalin in H441 tumor-bearing mice effectively suppressed cancer growth...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181298.
Published: 08 February 2019
...Zhenhua Fei; Wei Gao; Raoying Xie; Ganzhu Feng; Xiaolin Chen; Yiyan Jiang Lung cancer has been one of the most common malignancies in the world. Cell senescence has been recognized as the avenue to inhibit tumor progression. However, the mechanisms remain poorly understood. In the present study, we...
Articles
FBXL19-AS1 exerts oncogenic function by sponging miR-431-5p to regulate RAF1 expression in lung cancer
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181804.
Published: 25 January 2019
...Qian Jiang; Li Cheng; Daiyuan Ma; Yanli Zhao Lung cancer is the leading cause of cancer-related mortality worldwide, characterized by uncontrolled proliferation and metastasis of lung cancer cells. Tumor angiogenesis plays a key role in proliferation and metastasis in cancers, and is an essential...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180853.
Published: 16 November 2018
..., identified in a genome-wide association study of prostate cancer, might be a common genetic risk factor for cancer risk. To address this issue, we here conducted a case–control study to investigate the association of POLR2E rs3787016 polymorphism with risk of liver and lung cancer (including 800 normal...
Includes: Supplementary data
Articles
circFADS2 regulates lung cancer cells proliferation and invasion via acting as a sponge of miR-498
Open Access
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180570.
Published: 31 August 2018
...Fucheng Zhao; Yanru Han; Zhenzhou Liu; Zhenxia Zhao; Zhuoran Li; Kui Jia CircRNAs could play critical functions in tumor progression. However, the expression and underlying mechanism of circRNAs in lung cancer progression remain poorly defined. In the present study, high-throughput microarray assay...
Articles
Identification of relevant prognostic values of cytokeratin 20 and cytokeratin 7 expressions in lung cancer
Open Access
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171086.
Published: 06 November 2017
...Hai-Tao Luo; Cai-Xia Liang; Rong-Cheng Luo; Wei-Guang Gu Lung cancer is one of the most common malignant tumors harmful to human health. Cytokeratin (CK) is highly conserved and differentiated related to the proliferation and differentiation of epithelial cells. The aim of the study was to explore...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (4): BSR20170852.
Published: 14 August 2017
... Hospital of Hebei University. The informed written consents were collected from all eligible patients and the entire study was performed based on the Declaration of Helsinki. biomarkers immunohistochemistry lung cancer PLK1 pronosis The incidence and mortality of lung cancer...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (4): BSR20170762.
Published: 14 August 2017
...Da Chen; Fangming Zhong; Ye Chen Calcium/calmodulin-dependent protein kinase (CAMK) kinase1 (CAMKK1) could specifically recognize and activate CAMK I and IV. Furthermore, the activation of CAMK showed positive correlation in proliferation of lung cancer (LC). In addition, a genome-wide association...
Articles
miRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homologue 1
Open Access
Journal:
Bioscience Reports
Biosci Rep (2016) 36 (3): e00354.
Published: 30 June 2016
... in lymphoma cells. However, this function has not been investigated in lung cancer cells. Microarray analysis was performed in A549 cells 48 h after exposure to 8 Gy of γ-irradiation or sham irradiation to identify differentially expressed miRNAs. miR-148b mimic and inhibitor were transfected, followed...
Includes: Supplementary data
Articles
Evidence of Mucin Secretion in Human Lung Adenocarcinoma Cell Lines NCIH650 and NCIH2077 and Effect of Select Secretagogues on Mucin Secretion
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1999) 19 (5): 473–483.
Published: 01 October 1999
... Publishing Corporation 1999 Mucin lung cancer gene expression secretion lung adenocarcinoma Bioscience Reports, Vol. 19, No. 5, 1999 Evidence of Mucin Secretion in Human Lung Adenocarcinoma Cell Lines NCIH650 and NCIH2077 and Effect of Select Secretagogues on Mucin Secretion Prerna M. Sharma,1...
