1-50 of 68
Keyword: Mitochondria
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
×Close Modal
Sort by
Journal Articles
Bioscience Reports (16 September 2019) 39 (9): BSR20192101.
Published: 16 September 2019
... its regulation of mitochondrial biology, including biogenesis, metabolism and apoptosis. In addition to regulating the expression of mitochondrial genes encoded in the nucleus, NF-κB signalling components are also found within mitochondria themselves and associated with mitochondrial DNA. However...
Journal Articles
Bioscience Reports (18 January 2019) 39 (1): BSR20181661.
Published: 18 January 2019
... mitochondria due to their relative negative charge. However, TMRE is poorly retained in fixed cells and was therefore only used by us to detect MMP dynamically in live cells. For fixed cells, we used the CMXRos (MitoTracker red) stain (excitation, 543 nm, emission, 633 nm; 500 nM in DMEM without phenol red for...
Journal Articles
Bioscience Reports (2 October 2018) 38 (5): BSR20171492.
Published: 02 October 2018
... radical (HOO∙). Their production sites in mitochondria are reviewed. Even though being highly toxic products, ROS seem important in transducing information from dysfunctional mitochondria. Evidences of signal transduction mediated by ROS in mitochondrial deficiency contexts are then presented in different...
Journal Articles
Bioscience Reports (29 June 2018) 38 (3): BSR20180208.
Published: 29 June 2018
...María Cecilia De Rossi; Valeria Levi; Luciana Bruno Molecular motors play relevant roles on the regulation of mitochondria size and shape, essential properties for the cell homeostasis. In this work, we tracked single rod-shaped mitochondria with nanometer precision to explore the performance of...
Includes: Multimedia, Supplementary data
Journal Articles
Bioscience Reports (31 May 2018) 38 (3): BSR20180503.
Published: 31 May 2018
.... Then, the MTT solution was removed and DMSO (100 μl) was added to each well to dissolve the MTT formazan. The absorbance was measured at 540 nm with a microplate reader. Apoptosis Caspase JNK Mitochondria p38 MARK Piperine Ovarian cancer remains the most lethal gynecologic...
Journal Articles
Bioscience Reports (21 February 2018) 38 (1): BSR20171666.
Published: 21 February 2018
...-domain. The interaction of HK2 with the mitochondria through its N-half is proposed to facilitate higher stability on the mitochondria. The identification of structural and biochemical differences between HK2 and other human hexokinase isozymes could potentially be used in the development of new...
Includes: Supplementary data
Journal Articles
Bioscience Reports (10 January 2018) 38 (1): BSR20171533.
Published: 10 January 2018
... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell differentiation Histone Methylarginine Mitochondria PGC-1a Skeletal muscle Cells were scraped in ice-cold RIPA...
Journal Articles
Bioscience Reports (12 December 2017) 37 (6): BSR20171006.
Published: 12 December 2017
... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioenergetics esophageal squamous cell carcinoma hypoxia mitochondria oxidative stress reactive oxygen species Esophageal...
Includes: Supplementary data
Journal Articles
Bioscience Reports (17 May 2017) 37 (3): BSR20170319.
Published: 17 May 2017
... an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Lon protease mitochondria mitochondrial DNA mitochondrial transcription factor A Tetramethylpyrazine Protein...
Includes: Supplementary data
Journal Articles
Bioscience Reports (15 April 2016) 36 (2): e00321.
Published: 15 April 2016
... the release of large quantities of amino acids, together with the haemoglobin prosthetic group, haem, which decomposes hydroperoxides and propagates oxygen-derived free radicals. Our previous studies demonstrated that reactive oxygen species (ROS) levels were diminished in the mitochondria and midgut...
Journal Articles
Bioscience Reports (16 March 2016) 36 (2): e00313.
Published: 16 March 2016
...Abena Nsiah-Sefaa; Matthew McKenzie Mitochondria provide the main source of energy to eukaryotic cells, oxidizing fats and sugars to generate ATP. Mitochondrial fatty acid β-oxidation (FAO) and oxidative phosphorylation (OXPHOS) are two metabolic pathways which are central to this process. Defects...
Journal Articles
Bioscience Reports (22 December 2015) 35 (6): e00277.
Published: 22 December 2015
... variants may be selected upon by dietary macronutrients could be intuitively consistent to some and counter intuitive to others, it must face a multitude of scientific hurdles before it can be recognized. diet epigenetics flavin-adenine dinucleotide (FAD) mitochondria retrograde response selection...
Journal Articles
Bioscience Reports (28 August 2015) 35 (4): e00244.
Published: 28 August 2015
...-adenine dinucleotide (FAD) binding mitochondria protein folding tryptophan residue thiol oxidase Erv1 (essential for respiration and viability 1) is an essential component of the mitochondrial import and assembly (MIA) pathway, playing a critical role during import and oxidative folding of the...
Includes: Supplementary data
Journal Articles
Bioscience Reports (7 August 2015) 35 (4): e00237.
Published: 07 August 2015
... patients. Bioenergetic Health Index cardiac surgery cardiomyocytes mitochondria monocytes pericardial fluid oxidative stress Cardiac surgery is a common procedure with a significant incidence of post-operative complications associated with increased morbidity and several complications...
Includes: Supplementary data
Journal Articles
Bioscience Reports (11 June 2015) 35 (3): e00200.
Published: 11 June 2015
... monitoring and precursor ion scans, with the ESI source being operated in the positive ion mode. energetics fetal programming heart metabolism mitochondria obesity The developmental programming hypothesis proposes that adverse influences during critical periods in development permanently...
Includes: Supplementary data
Journal Articles
Bioscience Reports (31 January 2014) 34 (1): e00092.
Published: 31 January 2014
...Hua Zhao; Kalani Ruberu; Hongyun Li; Brett Garner Cbl (cobalamin) utilization as an enzyme cofactor is dependent on its efficient transit through lysosomes to the cytosol and mitochondria. We have previously proposed that pathophysiological perturbations in lysosomal function may inhibit...
Journal Articles
Bioscience Reports (15 November 2013) 33 (6): e00080.
Published: 15 November 2013
... anabolic pathways that provide precursors for the synthesis of lipids, proteins and DNA. The review will discuss the original ideas of Otto Warburg and how they initially led to the notion that mitochondria of tumour cells were dysfunctional. Data will be presented to show that not only the organelles are...
Journal Articles
Bioscience Reports (25 July 2013) 33 (4): e00052.
Published: 25 July 2013
... oxidation ethylmalonic encephalopathy hydrogen sulfide mitochondria redox regulation sulfur dioxygenase ETHE1 is a mitochondrial SDO (sulfur dioxygenase) [ 1 ], which takes part in sulfide detoxification by oxidizing persulfides to sulfite [ 2 ]. Animal cells produce H 2 S during the catabolism...
Journal Articles
Bioscience Reports (13 December 2012) 33 (1): e00008.
Published: 13 December 2012
... and three 40% CR groups) and the CR groups were fed diets containing soya bean oil (also in the control diet), fish oil or lard. The fatty acid composition of the major mitochondrial phospholipid classes, proton leak and H 2 O 2 production were measured in liver mitochondria following 1 month of CR...
Journal Articles
Bioscience Reports (19 September 2012) 32 (6): 549–557.
Published: 19 September 2012
...J. Ignacio Moreno; Babu Patlolla; Kerry R. Belton; Brenita C. Jenkins; Polina V. Radchenkova; Marta A. Piva Ccm1p is a nuclear-encoded PPR (pentatricopeptide repeat) protein that localizes into mitochondria of Saccharomyces cerevisiae . It was first defined as an essential factor to remove the bI4...
Journal Articles
Bioscience Reports (10 October 2011) 32 (1): 53–59.
Published: 10 October 2011
...Leopoldo De Meis; Luisa A. Ketzer; Juliana Camacho-Pereira; Antonio Galina The UCP1 [first UCP (uncoupling protein)] that is found in the mitochondria of brown adipocytes [BAT (brown adipose tissue)] regulates the heat production, a process linked to non-shivering thermogenesis. The activity of...
Journal Articles
Bioscience Reports (5 August 2011) 31 (5): 429–437.
Published: 05 August 2011
... mutant form can suppress the processing of the immature form of uMtCK. LRRK2 expression keeps the uMtCK preprotein on the outer mitochondrial membrane instead of entering the mitochondria. In addition, the expression of both wild-type and mutant forms of LRRK2 promotes the interaction between ANT and...
Includes: Supplementary data
Journal Articles
Bioscience Reports (29 October 2010) 31 (2): 87–98.
Published: 29 October 2010
... cytochrome c protein from the mitochondria to the cytoplasm. Histological observation by TUNEL and EM proved that NaHS inhibited cardiac apoptosis in HF hearts and improved mitochondrial derangements, but that PAG aggravated those indices. Hence, H 2 S has protective effects in HF rats. 1 To whom...
Journal Articles
Bioscience Reports (27 September 2010) 30 (6): 413–423.
Published: 27 September 2010
...) mitochondria skeletal muscle thermal acclimation HK (hexokinase) is a ubiquitous enzyme found in all eukaryotic cells and is also widespread in prokaryotic organisms. This enzyme is responsible for the conversion of glucose into G6P (glucose 6-phosphate) using ATP as a phosphate donor. Almost all...
Journal Articles
Bioscience Reports (22 July 2009) 29 (6): 351–362.
Published: 22 July 2009
... species and subsequent death through an oxidative mechanism [ 18 ]. They found that erastin alters the permeability of the outer mitochondrial membrane in purified mitochondria expressing a single VDAC isoform. Using a radiolabelled analogue and a filter-binding assay, they showed that erastin binds...
Journal Articles
Bioscience Reports (11 September 2008) 28 (5): 239–249.
Published: 11 September 2008
...Catherine Ross-Inta; Chern-Yi Tsai; Cecilia Giulivi Mitochondria can synthesize a limited number of proteins encoded by mtDNA (mitochondrial DNA) by using their own biosynthetic machinery, whereas most of the proteins in mitochondria are imported from the cytosol. It could be hypothesized that the...
Includes: Supplementary data
Journal Articles
Bioscience Reports (29 April 2008) 28 (2): 83–88.
Published: 29 April 2008
... proton leak by HNE in rat and mouse skeletal muscle mitochondria is dependent on incubation with respiratory substrate. In the presence of HNE, mitochondria energized with succinate became progressively more leaky to protons over time compared with mitochondria in the absence of either HNE or succinate...
Journal Articles
Bioscience Reports (13 June 2007) 27 (1-3): 87–104.
Published: 13 June 2007
...Lucia Petrozzi; Giulia Ricci; Noemi J. Giglioli; Gabriele Siciliano; Michelangelo Mancuso Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. However, despite the evidence of morphological, biochemical and molecular abnormalities in...
Journal Articles
Bioscience Reports (13 June 2007) 27 (1-3): 11–21.
Published: 13 June 2007
..., providing a summary of practical tips that should precede data acquisition and subsequent analysis. Furthermore, we discuss the application and feasibility of various techniques and discuss their respective strength and weakness. © 2007 The Biochemical Society 2007 Membrane potential Mitochondria...
Journal Articles
Bioscience Reports (13 June 2007) 27 (1-3): 165–171.
Published: 13 June 2007
... disorders are also reported. © 2007 The Biochemical Society 2007 Mitochondria Stem cells Differentiation Mitochondrial localization ROS MNGIE MINI REVIEW The Role of Mitochondria in Stem Cell Biology Claudia Nesti Æ Livia Pasquali Æ Francesca Vaglini Æ Gabriele Siciliano Æ Luigi Murri...
Journal Articles
Bioscience Reports (13 June 2007) 27 (1-3): 139–150.
Published: 13 June 2007
... of exercise training for patients with mtDNA defects, and the prevention of mtDNA disease transmission. © 2007 The Biochemical Society 2007 Mitochondria mtDNA Mutation Heteroplasmy Treatment Exercise Satellite cell ORI GI N A L P A PE R Experimental Strategies Towards Treating...
Journal Articles
Bioscience Reports (9 November 2006) 26 (5): 341–367.
Published: 09 November 2006
... Media, LLC 2006 Alzheimer's disease Parkinson's disease Amyotrophic lateral Sclerosis Huntington's disease Prion diseases Neurodegeneration Genetics Mitochondria Environmental factors Abstract Neurodegenerative diseases are a heterogeneous group of pathologies which includes complex...
Journal Articles
Bioscience Reports (18 August 2006) 26 (3): 231–243.
Published: 18 August 2006
... methanesulfonate (MitoDNP). TPP cations accumulate within mitochondria driven by the membrane potential (Δ ψ ), the predominant component of Δ p . Our hypothesis was that MitoDNP would accumulate in mitochondria at high Δ ψ where it would act as a protonophore, but that at lower Δ ψ the accumulation and uncoupling...
Journal Articles
Bioscience Reports (8 June 2005) 25 (3-4): 209–226.
Published: 08 June 2005
...Fábio T. S. Nogueira; Jiri Borecký; Aníbal E. Vercesi; Paulo Arruda Uncoupling mitochondrial proteins (UCPs) belong to a discrete family within the mitochondrial anion carrier superfamily. Several uncoupling protein types have been found in mitochondria from mammals and plants, as well as in fishes...
Journal Articles
Bioscience Reports (8 June 2005) 25 (3-4): 271–286.
Published: 08 June 2005
...Jiří Borecký; Aníbal E. Vercesi Energy-dissipation in plant mitochondria can be mediated by inner membrane proteins via two processes: redox potential-dissipation or proton electrochemical potential-dissipation. Alternative oxidases (AOx) and the plant uncoupling mitochondrial proteins (PUMP...
Journal Articles
Bioscience Reports (1 April 2004) 24 (2): 117–125.
Published: 01 April 2004
... respiratory activity. The oxidative phosphorylation system dominated in the energy budget of the cell. A procedure was specially design to isolate tightly coupled mitochondria from yeast cells grown at alkaline conditions. The isolated mitochondrial preparations met known criteria of physiological intactness...
Journal Articles
Bioscience Reports (1 April 2003) 23 (2-3): 103–117.
Published: 01 April 2003
...Vitaly D. Samuilov; Elena M. Lagunova; Dmitry B. Kiselevsky; Elena V. Dzyubinskaya; Yana V. Makarova; Mikhail V. Gusev Mitochondria are known to participate in the initiation of programmed cell death (PCD) in animals and in plants. The role of chloroplasts in PCD is still unknown. We describe a new...
Journal Articles
Bioscience Reports (1 February 2002) 22 (1): 3–16.
Published: 01 February 2002
...S. Papa; S. Scacco; A.M. Sardanelli; V. Petruzzella; R. Vergari; A. Signorile; Z. Technikova-Dobrova A cAMP-dependent protein kinase (PKA) is localized in mammalian mitochondria with the catalytic site at the matrix side of the membrane where it phosphorylates a number of proteins. One of these is...
Journal Articles
Bioscience Reports (1 February 2002) 22 (1): 99–113.
Published: 01 February 2002
...Frank Norbert Gellerich; Sonata Trumbeckaite; Jens Rüdiger Opalka; Johannes Frank Gellerich; Ying Chen; Stephan Zierz; Karl Werdan; Christiane Neuhof; Heinz Redl Mitochondria, that provide most of the ATP needed for cell work, and that play numerous specific functions in biosyntheses and...
Journal Articles
Bioscience Reports (1 February 2002) 22 (1): 33–46.
Published: 01 February 2002
... Fatty acid mitochondria UCP2 & 3 uncoupling protein Bioscience Reports, Vol. 22, No. 1, February 2002 ( 2002) MINI REVIEW Reconstitution of Novel Mitochondrial Uncoupling Proteins UCP2 and UCP3 Marke´ta Z a´c kova1 and Petr Jez ek2,3 Receiûed September 13, 2001 Reconstitution of novel...
Journal Articles
Bioscience Reports (1 February 2002) 22 (1): 47–58.
Published: 01 February 2002
... of cell survival and cell death signals. © 2002 Plenum Publishing Corporation 2002 Apoptosis Bcl-2 mitochondria permeability VDAC Bioscience Reports, Vol. 22, No. 1, February 2002 ( 2002) MINI REVIEW Bcl-2 Family of Proteins: Life-or-Death Switch in Mitochondria Yoshihide Tsujimoto...
Journal Articles
Bioscience Reports (1 April 2001) 21 (2): 189–194.
Published: 01 April 2001
... mitochondria, which results in hypothermia. © 2001 Plenum Publishing Corporation 2001 Uncoupling proteins thermoregulation fatty acids mitochondria skeletal muscle brown fat Bioscience Reports, Vol. 21, No. 2, April 2001 ( 2001) MINI REVIEW Barbara Cannon s Data on the UCP1-Ablated Mice: Non...
Journal Articles
Bioscience Reports (1 April 2001) 21 (2): 201–212.
Published: 01 April 2001
...Jirí Borecký; Ivan G. Maia; Paulo Arruda Uncoupling proteins (UCPs) belong to a distinct cluster of the mitochondrial anion carrier family. Up to five different uncoupling protein types were found in mitochondria of mammals and plants, and recently in fishes, fungi and protozoa. They exhibit a...
Journal Articles
Bioscience Reports (1 April 2001) 21 (2): 213–222.
Published: 01 April 2001
... thermogenesis is restricted not only by a lower-limit size but also by a kinetically-limited stimulation of the mitochondrial respiratory chain. © 2001 Plenum Publishing Corporation 2001 Alternative oxidase uncoupling protein mitochondria Bioscience Reports, Vol. 21, No. 2, April 2001 ( 2001) MINI...
Journal Articles
Bioscience Reports (1 February 2001) 21 (1): 73–80.
Published: 01 February 2001
... isolated rat liver mitochondria, characterized by membrane depolarization, release of matrix calcium, and osmotic swelling. All these events were blocked by cyclosporine A (CyA) and the calcium uniporter inhibitor ruthenium red (RR). The results suggest that CDCA increases the sensitivity of isolated...
Journal Articles
Bioscience Reports (1 April 1999) 19 (2): 89–98.
Published: 01 April 1999
...I. Rustenbeck; C. Dickel; C. Herrmann; T. Grimmsmann Experiments with inside-out patches excised from pancreatic B-cells have yielded evidence that mitochondria are often contained in the cytoplasmic plug protruding into the tip of patch pipette. When intact B-cells were loaded with the fluorescent...
Journal Articles
Bioscience Reports (1 December 1998) 18 (6): 329–340.
Published: 01 December 1998
... necrosis factor mitochondria autophagy apoptosis necrosis Bioscience Reports, Vol. 18, No. 6, 1998 Tumor Necrosis Factor-Induced Cytotoxicity is Not Related to Rates of Mitochondrial Morphological Abnormalities or Autophagy-Changes that can be Mediated by TNFR-I or TNFR-II Johannes B. Prins,1,2,4...
Journal Articles
Bioscience Reports (1 October 1998) 18 (5): 251–263.
Published: 01 October 1998
... induced by the peptide are the same as those involved in the formation of contact sites between mitochondrial membranes during the import of nuclear coded proteins. © 1998 Plenum Publishing Corporation 1998 Membrane insertion membrane junctions mitochondria cytochrome c oxidase p25 peptide...
Journal Articles
Bioscience Reports (1 December 1997) 17 (6): 521–527.
Published: 01 December 1997
... uncoupling, and the physiological importance of this process, are discussed. © 1997 Plenum Publishing Corporation 1997 Glyceraldehyde-3-phosphate dehydrogenase glycolysis oxidation uncoupling thiols hydrogen peroxide mitochondria Bioscience Reports. Vol. 17. No. 6. 1997 HYPOTHESIS An...
Journal Articles
Bioscience Reports (1 December 1997) 17 (6): 529–535.
Published: 01 December 1997
... insulin. There was also no correlation between the degree of relationship (of the taxa) and the dehydrogenase profile after insulin treatment. © 1997 Plenum Publishing Corporation 1997 Mitochondria mt-dehydrogenase evolution insulin hormonal effect Bioscience Reports, Vol. 17, No. 6, 1997...