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Keywords: NADPH
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Articles

PGC-1α limits angiotensin II-induced rat vascular smooth muscle cells proliferation via attenuating NOX1-mediated generation of reactive oxygen species

Open Access
Qingbin Zhao, Junfang Zhang, Huifang Wang
Journal: Bioscience Reports
Biosci Rep (2015) 35 (5): e00252.
https://doi.org/10.1042/BSR20150112
Published: 29 September 2015
... was negatively correlated with an increase in cell proliferation and migration induced by AngII. Overexpression of PGC-1α inhibited AngII-induced proliferation and migration, ROS generation and NADPH oxidase activity in VSMCs. Conversely, Ad-shPGC-1α (adenovirus-mediated PGC-1α-specific shRNA) led...
View articletitled, PGC-1α limits angiotensin II-induced rat vascular smooth muscle cells proliferation via attenuating NOX1-mediated generation of reactive oxygen species
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Includes: Supplementary data