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Keywords: Notch
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Articles

LncRNA SRA mediates cell migration, invasion, and progression of ovarian cancer via NOTCH signaling and epithelial–mesenchymal transition

Open Access
Lee Kyung Kim, Sun-Ae Park, Yoolhee Yang, Young Tae Kim, Tae-Hwe Heo, Hee Jung Kim
Journal: Bioscience Reports
Biosci Rep (2021) 41 (9): BSR20210565.
https://doi.org/10.1042/BSR20210565
Published: 06 September 2021
..., and invasion. Both in vivo and in vitro experiments using knockdown and overexpression showed that SRA potently regulated epithelial–mesenchymal transition (EMT) and NOTCH pathway components. Further, clinical data confirmed that SRA was a significant predictor of overall survival (OS) and progression-free...
View articletitled, LncRNA SRA mediates cell migration, invasion, and progression of ovarian cancer via NOTCH signaling and epithelial–mesenchymal transition
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Includes: Supplementary data
Articles

Effects of microRNA-208a on inflammation and oxidative stress in ketamine-induced cardiotoxicity through Notch/NF-κB signal pathways by CHD9

Open Access
Hongjie Yuan, Shibin Du, Youliang Deng, Xiaoqing Xu, Qian Zhang, Miao Wang, Ping Wang, Yi Su, Xiao Liang, Yanyan Sun, Zhengzhuang An
Journal: Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182381.
https://doi.org/10.1042/BSR20182381
Published: 17 May 2019
..., and induced p65 protein expression in vitro model. Overexpression of CHD9 reduced the effects of microRNA-208a on inflammation and oxidative stress in heart cell through Notch/p65 signal pathways. Notch1 activation reduced the effects of microRNA-208a on inflammation and oxidative stress in heart cell through...
View articletitled, Effects of microRNA-208a on inflammation and oxidative stress in ketamine-induced cardiotoxicity through Notch/NF-κB signal pathways by CHD9
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Articles

Drosophila neuroblasts as a new model for the study of stem cell self-renewal and tumour formation

Open Access
Song Li, Hongyan Wang, Casper Groth
Journal: Bioscience Reports
Biosci Rep (2014) 34 (4): e00125.
https://doi.org/10.1042/BSR20140008
Published: 29 July 2014
... neuroblasts [ 60 ]. Moreover, PP2A can directly dephosphorylate Numb to facilitate the repression of neuroblast self-renewal [ 61 ]. asymmetric division differentiation neural stem cell neuroblast Notch self-renewal tumour formation Another protein phosphatase reported to mediate...
View articletitled, Drosophila neuroblasts as a new model for the study of stem cell self-renewal and tumour formation
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