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Keywords: PI3K/Akt signaling pathway
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Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (12): BSR20221443.
Published: 12 December 2022
... BY) . cerebral ischemic/reperfusion injury endoplasmic reticulum stress leptin PI3K/Akt signaling pathway Stroke accounts for almost 5% of all disability-adjusted life years [ 1 ]. With enhanced aging of the population and changes in lifestyle, the incidence and mortality rate of stroke are increasing...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20193899.
Published: 15 June 2020
..., migration, and phenotype switching of ASMCs via inhibiting the PI3K/Akt signaling pathway. Thus, Gal-1 might be a promising target for the treatment of asthma. A total of 24 cases of children asthma patients and 18 cases of respiratory nonasthmatic patients were obtained from the Pediatric Respiratory...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181122.
Published: 12 February 2019
... License 4.0 (CC BY) . An increasing number of reports have indicated that the phosphatidylinositol3-kinase (PI3K)/Akt signaling pathway is involved in cell survival and apoptosis [ 13 , 14 ]. Activation of PI3K/Akt signaling blocks the mitochondrial apoptotic pathway. Furthermore, inhibition of PI3K...