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Keywords: Renin-angiotensin system
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Articles

Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm

Open Access
Anshul S. Jadli, Karina P. Gomes, Noura N. Ballasy, Tishani Methsala Wijesuriya, Darrell Belke, Paul W.M. Fedak, Vaibhav B. Patel
Journal: Bioscience Reports
Biosci Rep (2023) 43 (11): BSR20230718.
https://doi.org/10.1042/BSR20230718
Published: 30 November 2023
...; increased Ang 1-7 activity may provide a promising therapeutic strategy against the progression of AAA. Abdominal aortic aneurysm Angiotensin 1-7 Mitochondrial fission Renin-angiotensin system Smooth muscle cells Cellular ROS generation was visualized using the previously described...
View articletitled, Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm
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Includes: Supplementary data
Articles

Evidence for a role of angiotensin converting enzyme 2 in proteinuria of idiopathic nephrotic syndrome

Open Access
Roberta da Silva Filha, Sérgio Veloso Brant Pinheiro, Thiago Macedo e Cordeiro, Victor Feracin, Érica Leandro Marciano Vieira, Aline Silva Miranda, Ana Cristina Simões e Silva
Journal: Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181361.
https://doi.org/10.1042/BSR20181361
Published: 03 January 2019
...Roberta da Silva Filha; Sérgio Veloso Brant Pinheiro; Thiago Macedo e Cordeiro; Victor Feracin; Érica Leandro Marciano Vieira; Aline Silva Miranda; Ana Cristina Simões e Silva Introduction: Renin angiotensin system (RAS) plays a role in idiopathic nephrotic syndrome (INS). Most studies investigated...
View articletitled, Evidence for a role of angiotensin converting enzyme 2 in proteinuria of idiopathic nephrotic syndrome
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Articles

20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats

Open Access
Lenka Sedláková, Soňa Kikerlová, Zuzana Husková, Lenka Červenková, Věra Čertíková Chábová, Josef Zicha, John R. Falck, John D. Imig, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, Vojtěch Krátký, Luděk Červenka, Libor Kopkan
Journal: Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20171496.
https://doi.org/10.1042/BSR20171496
Published: 12 September 2018
... to come. It will be recalled that seminal studies from Laragh group revealed that abnormal activation of the renin–angiotensin system (RAS) plays a crucial role in the pathophysiology of malignant hypertension [ 9 , 10 ] and the notion that inappropriate activation of the RAS importantly contributes...
View articletitled, 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats
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Articles

Unexpected role of the human cytomegalovirus contribute to essential hypertension in the Kazakh Chinese population of Xinjiang

Open Access
Qian Feng, Jing Hui, Na Tang, Yong-Min Liu, Hua Zhong, Zhen Li, La-Mei Wang, Yuan-Yuan Qu, Feng-Mei Deng, Fang He
Journal: Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20171522.
https://doi.org/10.1042/BSR20171522
Published: 27 June 2018
...Qian Feng; Jing Hui; Na Tang; Yong-Min Liu; Hua Zhong; Zhen Li; La-Mei Wang; Yuan-Yuan Qu; Feng-Mei Deng; Fang He Human cytomegalovirus (HCMV) infection, chronic inflammation and oxidative stress, the renin–angiotensin system (RAS), endothelial function, and DNA methylation play roles...
View articletitled, Unexpected role of the human cytomegalovirus contribute to essential hypertension in the Kazakh Chinese population of Xinjiang
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Articles

On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone

Open Access
Tadashi Konoshita, Saori Kaeriyama, Machi Urabe, Takahiro Nakaya, Mika Yamada, Mai Ichikawa, Katsushi Yamamoto, Satsuki Sato, Michiko Imagawa, Miki Fujii, Yasukazu Makino, Yasuo Zenimaru, Shigeyuki Wakahara, Jinya Suzuki, Tamotsu Ishizuka, Hiroyuki Nakamura, for the Genomic Disease Outcome Consortium (G-DOC) Study Investigators
Journal: Bioscience Reports
Biosci Rep (2016) 36 (5): e00381.
https://doi.org/10.1042/BSR20160129
Published: 16 September 2016
... Consortium (G-DOC) Study Investigators The activation of the renin–angiotensin system (RAS) is one of the unfavourable characteristics of calcium channel blocker (CCB). N type calcium channel is thought to be involved in renin gene transcription and adrenal aldosterone release. Accordingly, N/L type CCB has...
View articletitled, On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone
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