... License 4.0 (CC BY) . muscle NCX phospholamban sarcolipin sarcoplasmic reticulum SERCA Calcium (Ca 2+ ) is a divalent cation which is indispensably involved with molecular signaling. Innately, Ca 2+ has flexibility in its bonding angles and lengths, allowing for an array of potential...

.... PKCδ was down-regulated by siRNA. RT-PCR and Western blotting were used to detect the expression of ERS markers. The fluorescence of Ca 2+ influx was recorded using confocal microscopy. Sarco-ER Ca 2+ -ATPase (SERCA) activity was measured by ultramicro-ATP enzyme test kit. PA treatment induced lipid...

...Frank Wuytack; Leonard Dode; Fouzia Baba-Aissa; Luc Raeymaekers Of all the SERCA pumps, SERCA3 was the latest to be described and the least well known. Its primary structure deviates more than usual from the other members of the SERCA family. It is not known whether its remarkably low affinity...