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Keywords: SGLT-2
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In Collection
Endothelin XVIII Conference Collection
Thomas L. Williams, Rhoda E. Kuc, Anna L. Paterson, George R. Abraham, Anna L. Pullinger, Janet J. Maguire, Sanjay Sinha, Peter J. Greasley, Philip Ambery, Anthony P. Davenport
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (6): BSR20240604.
Published: 31 May 2024
... (SGLT-2i). These drugs primarily inhibit the SGLT-2 transporter that, in humans, is thought to be mainly restricted to the renal proximal convoluted tubule, resulting in increased glucose excretion favouring improved glycaemic control and diuresis. This action reduces fluid retention with ET receptor...
Includes: Supplementary data