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Amal Ahmed Mohamed, Wafaa Gh. Shousha, Moushira Erfan Zaki, Hala T. El-Bassyouni, Hadeel El-Hanafi, Sara M. Abdo
Biosci Rep (2020) 40 (9): BSR20192910.
Published: 21 September 2020
... subjects. Anthropometric measurements were recorded and serum levels of tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), interleukin (IL) 6 (IL-6), IL-12, soluble intercellular adhesion molecule 1 (sICAM-1) and soluble vascular adhesion molecule 1 (sVCAM-1) were assessed among participants...
Biosci Rep (2020) 40 (9): BSR20202551.
Published: 18 September 2020
... levels of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α) and fibronectin (FN) levels in the glomeruli and serum levels of the anti-dsDNA antibody were determined. Mesangial cells (MCs) were cultured in vitro , and IgG-type anti-dsDNA antibody and/or emodin were added to the...
Biosci Rep (2020) 40 (6): BSR20194472.
Published: 18 June 2020
... Myc-related signaling pathways. Biological behaviors of H9c2 cells were observed with the support of cell counting kit-8, MTT and flow cytometry. Expression levels of cytokines including TNF-α and ILs were evaluated by enzyme-linked immunosorbent assay. Western blot was applied to detect the...
Narisara Paradee, Niramon Utama-ang, Chairat Uthaipibull, John B. Porter, Maciej W. Garbowski, Somdet Srichairatanakool
Biosci Rep (2020) 40 (5): BSR20192110.
Published: 29 May 2020
... their glycosides, which exhibit antioxidant activity. The goal of the present study was to investigate the effects of the extracts on endothelial activation and EMPs generation in tumour necrosis factor-α (TNF-α)-induced EA.hy926 cells. We found that TNF-α (10 ng/ml) activated EA.hy926 cells and...
Jun Yao, Ruoyu Gao, Minghan Luo, Defeng Li, Liliangzi Guo, Zichao Yu, Feng Xiong, Cheng Wei, Benhua Wu, Zhenglei Xu, Dingguo Zhang, Jianyao Wang, Lisheng Wang
Biosci Rep (2020) 40 (4): BSR20192257.
Published: 07 April 2020
... (IBD). IBD tissues were obtained from IBD patients, followed by CD4 + cells isolation. Then, qRT-PCR and ELISA were used to detect the expression of miR-802, suppressor of cytokine signaling 5 (SOCS5), interleukin (IL)-17A and tumor necrosis factor (TNF)-α. Transfection of miR-802 mimics and miR-802...
Biosci Rep (2020) 40 (2): BSR20191726.
Published: 04 February 2020
...Jingjing Xie; Bo Li; Bing Yao; Pingchao Zhang; Lixin Wang; Hua Lu; Xuan Song Background: During disc degeneration, inflammatory cytokine tumor necrosis factor (TNF)-α is correlated with nucleus pulposus (NP) cell apoptosis. Transforming growth factor (TGF)-β1 has the potential to regenerate...
Biosci Rep (2019) 39 (12): BSR20191301.
Published: 20 December 2019
...Xiaoliang Guo; Chenxi Li; Jiawei Wu; Qingbu Mei; Chang Liu; Wenjing Sun; Lidan Xu; Songbin Fu Tumor necrosis factor-α (TNF-α) is involved in insulin resistance and has long been a candidate gene implicated in type 2 diabetes mellitus (T2DM), however the association between TNF-α polymorphisms -308G...
Biosci Rep (2019) 39 (9): BSR20192466.
Published: 24 September 2019
..., glypican 3 (GPC3), nuclear factor κ-light-chain-enhancer of activated B cells (NF-kB), epidermal growth factor receptor, ERK1/2, tumor necrosis factor-α (TNF-α), regenerating islet-derived 1 and 3 α (REG1A and 3A), substance P (SP)/neurokinin-1 receptor and PARP-1. The present review describes the key role...
Biosci Rep (2019) 39 (2): BSR20181202.
Published: 01 February 2019
...Uzma Zafar; Saba Khaliq; Hafiz Usman Ahmad; Khalid Pervaiz Lone Aim: To identify genetic variants in promoter areas of IL-6 -174 G>C and TNF-α -308 G>A in metabolic syndrome (Met S) and controls and associate them with Met S and serum cytokine levels. It was a cross-sectional study, including...
Biosci Rep (2018) 38 (6): BSR20181530.
Published: 21 November 2018
... pathway. Methods: Rat NP cells were cultured in medium with or without inflammatory cytokine tumor necrosis factor (TNF)-α for 6 days. The exogenous TNF-α was added into the medium to investigate its protective effects. NP cell apoptosis was evaluated by cell apoptosis ratio, caspase-3 activity, gene...
Poulami Majumder, Keheibamding Thou, Mandar Bhattacharya, Vineet Nair, Sujay Ghosh, Subrata Kumar Dey
Biosci Rep (2018) 38 (4): BSR20171212.
Published: 31 July 2018
...Poulami Majumder; Keheibamding Thou; Mandar Bhattacharya; Vineet Nair; Sujay Ghosh; Subrata Kumar Dey Background: Periodontitis is a very common inflammatory oral disease. Tumor necrosis factor-α (TNF-α) is a cytokine that has been involved with the gingival tissue destruction and remodeling...
Anna Beatriz Santana Luz, Júlia Braga dos Santos Figueredo, Bianca Damásio Pereira Dantas Salviano, Ana Júlia Felipe Camelo Aguiar, Luiza Gabriella Soares Dantas Pinheiro, Matheus Felipe Dantas Krause, Christina da Silva Camillo, Fernando Vagner Lobo Ladd, Raul Hernandes Bortolin, Vivian Nogueira Silbiger, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais
Biosci Rep (2018) 38 (3): BSR20180304.
Published: 27 June 2018
... =10) received for 17 weeks: (1) HGLI diet or (2) Standard diet (Labina®). Histological analyses of adipose tissue, jejunum, liver, and pancreas were performed. Stereology analysis, visceral adiposity index, gene expression, and immunohistochemistry of tumor necrosis factor-α (TNF-α) in visceral...
Biosci Rep (2018) 38 (3): BSR20180288.
Published: 12 June 2018
...Shili Zhao; Junxia Feng; Qi Wang; Lu Tian; Yunfang Zhang; Hongyan Li Apoptosis of podocytes contributes to proteinuria in many chronic kidney diseases. The cytokine, tumor necrosis factor-α (TNF-α) is thought to be involved in podocyte apoptosis, but the underlying mechanism is not understood. In...
Biosci Rep (2017) 37 (2): BSR20160440.
Published: 27 March 2017
...Hong-Wei Yang; Ying-Xue Wang; Jie Bao; Shu-Hui Wang; Ping Lei; Zhao-Lin Sun The present study aims to explore the correlation of human leucocyte antigen ( HLA ) -DQ and tumour necrosis factor ( TNF ) -α gene polymorphisms with ocular myasthenia gravis (OMG) combined with thyroid-associated...
Biosci Rep (2016) 36 (1): e00301.
Published: 29 February 2016
... factor-α (TNF-α) synthesis and TNF-α has been shown to regulate NAD + homoeostasis providing a link between a pro-inflammatory response and redox status. In the present study, we have used THP-1 differentiation into pro- (M1-like) and anti- (M2-like) inflammatory macrophage subset models to investigate...
Biosci Rep (1999) 19 (1): 35–42.
Published: 01 February 1999
...E. Carlstedt; P. Ridefelt; L. Lind; J. Rastad Calcium disturbances in the critically ill coincide with elevations of proinflammatory cytokines. The effects of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) on parathyroid hormone (PTH) secretion were investigated. IL-6 and TNF-α had no...