1-1 of 1
Keywords: Toll-like receptor 4 (TLR4).
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipidinduced inflammation and insulin resistance in muscle cells

Open Access
Sophie E. Hussey, Hanyu Liang, Sheila R. Costford, Amira Klip, Ralph A. DeFronzo, Alicia Sanchez-Avila, Brian Ely, Nicolas Musi
Journal: Bioscience Reports
Biosci Rep (2013) 33 (1): e00004.
https://doi.org/10.1042/BSR20120098
Published: 30 November 2012
... protein kinase (MAPK) nuclear factor κB (NF-κB) saturated non-esterified fatty acid (NEFA) Toll-like receptor 4 (TLR4). Insulin resistance is a characteristic feature of obesity and Type 2 diabetes mellitus. Skeletal muscle is the main site responsible for insulin-stimulated glucose disposal...
View articletitled, TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipidinduced inflammation and insulin resistance in muscle cells
Open the PDF for TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipidinduced inflammation and insulin resistance in muscle cells in another window
Includes: Supplementary data