Skip Nav Destination
Close Modal
Update search
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
NARROW
Format
Subjects
Article Type
Date
Availability
1-13 of 13
Keywords: WGCNA
Close
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Sort by
Articles
AKR1B10 regulates M2 macrophage polarization to promote the malignant phenotype of gastric cancer
Open Access
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (10): BSR20222007.
Published: 28 September 2023
... Atlas (TCGA) database. Differentially expressed genes (DEGs) were seared by combing the TCGA database and the Gene Expression Omnibus (GEO) database, and the key molecule AKR1B10 was identified by weighted gene coexpression network analysis (WGCNA). The biological functions of AKR1B10 in stomach...
Articles
Identification of potential M2 macrophage-associated diagnostic biomarkers in coronary artery disease
Open Access
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (12): BSR20221394.
Published: 12 December 2022
... in CAD. Methods: Transcriptome profile of CAD and control samples were downloaded from Gene Expression Omnibus database. The proportion of immune cells was analyzed using cell type identification by estimating relative subsets of RNA transcripts. Weighted Gene Co-expression Network Analysis (WGCNA...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (4): BSR20204293.
Published: 09 April 2021
... from the GSE62229 dataset, a co-expression network was conducted for downstream analysis using the ‘WGCNA’ R package. WGCNA could effectively combine gene expression information with the clinicopathological features to identify potential modules. Next, Gene Ontology (GO) and Kyoto Encyclopedia of Genes...
Includes: Supplementary data
Articles
Mining the key genes for ventilator-induced lung injury using co-expression network analysis
Open Access
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (3): BSR20203235.
Published: 17 March 2021
... pathogenesis, which might contribute to its future prevention and treatment. Four microarray datasets from the GEO database were selected in our investigation, and were subjected to the Weighted Gene Co-Expression Network Analysis (WGCNA) to identify the VILI-correlated gene modules. The limma package in R...
Articles
A panel of two miRNAs correlated to systolic blood pressure is a good diagnostic indicator for stroke
Open Access
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203458.
Published: 12 January 2021
... utilized the WGCNA to identify hub miRNAs correlated to systolic blood pressure (SBP). Differential analysis was applied to highlight hub differentially expressed miRNAs (DE-miRNAs), whereby we built a miRNA-based diagnostic indicator for stroke using bootstrap ranking Least Absolute Shrinkage...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20203263.
Published: 13 November 2020
... Cancer Genome Consortium (ICGC) databases. The prognosis-related genes with differential expression were identified with weighted gene co-expression network analysis (WGCNA), univariate analysis, the least absolute shrinkage and selection operator (LASSO). With the stepwise regression analysis, a risk...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20202044.
Published: 01 September 2020
..., there is no effective treatment due to the complexity of its etiology. Hence, the pathogenic mechanisms remain to be clearly defined. In the present study, we adopted an advanced analytical method—Weighted Gene Co-expression Network Analysis (WGCNA) to identify the key gene modules and hub genes associated with CRC...
Articles
Weighted gene co-expression network analysis to define pivotal modules and genes in diabetic heart failure
Open Access
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20200507.
Published: 07 July 2020
... were analyzed to identify key genes using the WGCNA method. Functional analyses were conducted on genes of the clinical interest modules via Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and Gene ontology (GO) enrichment, associated with protein–protein interaction (PPI) network construction...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20200124.
Published: 25 June 2020
... the role of miR-331-3p in HCC through weighted gene coexpression network analysis (WGCNA) based on The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO) and Oncomine. WGCNA was applied to build gene co-expression networks to examine the correlation between gene sets and clinical characteristics...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20193938.
Published: 15 June 2020
... and treatment of REPL. The chip data of REPL (GSE63901) were downloaded from the NCBI Gene Expression Omnibus (GEO) database. Weighted Gene Co-Expression Network Analysis (WGCNA) was used to construct a co-expression module for studying the relationship between gene modules and clinical features. In addition...
Includes: Supplementary data
Articles
Association between SNAP25 and human glioblastoma multiform: a comprehensive bioinformatic analysis
Open Access
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20200516.
Published: 09 June 2020
... the “WGCNA” package. Next, the protein–protein interaction (PPI) was assessed using Search Tool for the Retrieval of Interacting Genes Database (STRING) and hub modules in Cytoscape were screened. The Venn diagram was plotted to showcase the overlapped hub DEGs in PPI network and TCGA. Univariate...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20200514.
Published: 07 May 2020
... the Creative Commons Attribution License 4.0 (CC BY) . acute lymphoblastic leukemia MLL rearrangement pediatric WGCNA Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among children [ 1 ]. Approximately 98...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20181925.
Published: 19 July 2019
... and each phenotype of BC cell lines was determined by WGCNA. Spearman’s correlation analysis was carried out to determine the association individual module and subtype of BC cell lines, which was the most relevant module between the module eigengene (ME) and clinical traits. Each subtype of BC has...
Includes: Supplementary data