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Keywords: actin
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Biosci Rep (2023) 43 (9): BSR20230057.
Published: 11 September 2023
... promoted cancer cell migration in vitro and metastasis in vivo . The latest research from Sabine’s team has demonstrated that in H1299 lung cancer cells, the mechanism by which ITPKA promoted migration and invasion was predominantly depending on the ability of binding to F-actin, which will induce cancer...
Biosci Rep (2023) 43 (2): BSR20222150.
Published: 09 February 2023
...-regulation is associated with bad prognosis and it has been shown that a high level of ITPKA increases migration and invasion of lung cancer cell lines. However, since ITPKA exhibits actin bundling and Ins(1,4,5)P 3 -kinase activity, it was not clear which of these activities account for ITPKA-promoted...
Includes: Supplementary data
Biosci Rep (2022) 42 (9): BSR20210848.
Published: 12 September 2022
... to maintaining cell homeostasis. Actin, a major constituent of the cytoskeleton, forms many different structures which are acutely sensitive to the cell environment. Furthermore, actin structures interact with and are critically important for the function and regulation of multiple factors involved with mRNA...
Biosci Rep (2019) 39 (1): BSR20181312.
Published: 30 January 2019
... forms of AKT are present in melanoma cells nuclei. Using mass spectrometry in combination with protein-crosslinking and co-immunoprecipitation, we identified a series of putative protein partners of nuclear AKT, including heterogeneous nuclear ribonucleoprotein (hnRNP), cytoskeleton proteins β-actin, γ...
Includes: Supplementary data
Biosci Rep (2019) 39 (1): BSR20181252.
Published: 08 January 2019
... 4 Fast Flow (GSH-Sepharose) was from GE Healthcare. EDTA-free Protease Inhibitor Cocktail was from Roche. Actin and calmodulin (CaM) were prepared as described previously [ 20 ]. Full-length and heavy meromyosin (HMM) fragments of rat Myo5b were expressed in sf9 insect cells using baculovirus...
Biosci Rep (2015) 35 (5): e00246.
Published: 10 September 2015
...Daisy N. Riquelme; Aaron S. Meyer; Melanie Barzik; Amy Keating; Frank B. Gertler The members of the actin regulatory family of Ena/VASP proteins form stable tetramers. The vertebrate members of the Ena/VASP family, VASP, Mena and EVL, have many overlapping properties and expression patterns...
Includes: Supplementary data
Biosci Rep (2002) 22 (5-6): 529–540.
Published: 01 December 2002
...Katarina Tejle; Karl-Eric Magnusson; Birgitta Rasmusson Phagocytosis by neutrophils, macrophages, and other professional phagocytes requires rapid remodeling of actin. Early phagosomes are surrounded by a rim of F-actin that is disassembled during phagosomoal maturation. Breakdown of periphagosomal...
Biosci Rep (1989) 9 (3): 307–313.
Published: 01 June 1989
... are assessment of aggregation and adhesion, secretion, arachidonate metabolism, coagulant activities and the characterization of surface membrane glycoproteins (Day and Rao, 1986). Here we measure alterations of the G-/F-actin equilibrium of platelets. High F-actin values of unstimulated platelets indicate...
Biosci Rep (1986) 6 (8): 721–726.
Published: 01 August 1986
...Michael R. Payne; Suzanne E. Rudnick Tropomyosin polymerization is inhibited by DNAse I, an endonuclease which also interacts with G-actin. A 1:4 molar ratio of DNAse I to adult chicken pectoralis muscle tropomyosin almost completely prevents the increased viscosity of tropomyosin under...
Biosci Rep (1986) 6 (5): 493–499.
Published: 01 May 1986
...C. Méjean; M. Boyer; J. P. Labbé; J. Derancourt; Y. Benyamin; C. Roustan The interaction of two different anti-actin antibody populations with the myosin subfragment 1-F-actin rigor complex has been studied. In contrast with the 1–7 sequence, the 18–28 sequence appears to be strongly implicated...