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1-31 of 31
Keywords: angiogenesis
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Articles
Low-dose alcohol exacerbates hyperdynamic circulation and shunting in non-alcoholic cirrhotic rats
Open AccessChon Kit Pun, Hui-Chun Huang, Ching-Chih Chang, Shao-Jung Hsu, Chiao-Lin Chuang, Yi-Hsiang Huang, Ming-Chih Hou, Fa-Yauh Lee
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (7): BSR20240354.
Published: 19 July 2024
... fibrosis in the sham or cirrhotic rats; however, it significantly increased splanchnic blood inflow ( P =0.034) and portosystemic collaterals ( P =0.001). Mesenteric angiogenesis and pro-angiogenic proteins were up-regulated in the alcohol-treated cirrhotic rats, and poorer collateral vasoresponsiveness...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (3): BSR-2018-0882_RET.
Published: 01 March 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . angiogenesis feedback NBAT1 Sox9 This article is being retracted from...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (9): BSR-2018-1260_COR.
Published: 06 September 2023
... angiogenesis breast cancer pAkt signaling trans-endothelium Yanghe Huayan Decoction After publication the authors identified that the data had been incorrectly calculated, the current result could not be generated from the raw data and that the title for the Histogram was incorrect...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (3): BSR20212808.
Published: 29 March 2022
... (CC BY) . adipogenesis ADSC angiogenesis necroptosis RIP3 Autologous fat transplantation (AFT) has been widely used in recent years. This technique is favored in aesthetic and reconstructive surgeries because of its comprehensive source of adipose tissue, relatively simple access...
Includes: Supplementary data
Articles
Isabel Witvrouwen, Dominique Mannaerts, Jessica Ratajczak, Evi Boeren, Ellen Faes, Amaryllis H. Van Craenenbroeck, Yves Jacquemyn, Emeline M. Van Craenenbroeck
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (8): BSR20210874.
Published: 12 August 2021
... and correlated with higher arterial stiffness. These findings suggest a post-transcriptional dysregulation of the VEGF pathway in PE and identify miR-16 and miR-200c as possible diagnostic biomarkers for PE. VEGF is an important regulator of the placentation process since it regulates angiogenesis and plays...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210126.
Published: 01 July 2021
...Meisi Huo; Kangkang Yu; Yahui Zheng; Lu Liu; Hao Zhao; Xiaoqi Li; Chong Huang; Jubo Zhang Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality, metastasis accounts for most of the cases. Angiogenesis plays an important role in cancer metastasis, but how tumor cells affect...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (4): BSR20204442.
Published: 07 April 2021
...Dengliang Lei; Yue Chen; Yang Zhou; Gangli Hu; Fang Luo Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal cancers worldwide. Neovascularization is closely related to the malignancy of tumors. We constructed a signature of angiogenesis-related long noncoding RNA (lncRNA...
Includes: Supplementary data
Articles
Tim-3 promotes tube formation and decreases tight junction formation in vascular endothelial cells
Open AccessYizi Cong, Xingmiao Wang, Suxia Wang, Guangdong Qiao, Yalun Li, Jianqiao Cao, Wenguo Jiang, Yuxin Cui
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20202130.
Published: 14 October 2020
..., Occludin and claudin 1 (CLND1). In conclusion, these findings suggested that Tim-3 may exert a positive role in angiogenesis and a negative role in TJ formation in vascular endothelial cells, which may provide novel strategies for the treatment of Tim-3-associated diseases. Cell proliferation...
Articles
p38 promoted retinal micro-angiogenesis through up-regulated RUNX1 expression in diabetic retinopathy
Open AccessWenjun Zou, Zhengwei Zhang, Shasha Luo, Libo Cheng, Xiaoli Huang, Nannan Ding, Jinjin Yu, Ying Pan, Zhifeng Wu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20193256.
Published: 05 May 2020
... study, we constructed a DR animal model and a model in HRMECs to investigate the relationship between p38 and RUNX1 in retinal micro-angiogenesis in diabetic retinopathy. We found that p38 could promote retinal micro-angiogenesis by up-regulating RUNX1 expression in diabetic retinopathy. This suggested...
Articles
Houshiheisan promotes angiogenesis via HIF-1α/VEGF and SDF-1/CXCR4 pathways: in vivo and in vitro
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (10): BSR20191006.
Published: 15 October 2019
... ( [email protected] ) 25 04 2019 17 09 2019 25 09 2019 The extension of blood vessels is another important manifestation in angiogenesis, in which chemokine family porteins play a prominent role during this process. Stromal cell derived factor-1 (SDF-1) is a representative...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190513.
Published: 10 July 2019
...Chang Dai; Qiaoyun Gong; Yan Cheng; Guanfang Su Roundabout4 (Robo4) is a transmembrane receptor that belongs to the Roundabout (Robo) family of axon guidance molecules. Robo4 is an endothelial-specific receptor that participates in endothelial cell migration, proliferation, and angiogenesis...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190155.
Published: 02 May 2019
...Cai Hai-rong; Huang Xiang; Zhang Xiao-rong Angiogenesis is a vital step during the process of oncogenesis of a lot of tumors, with no exception in bladder cancer. One of the useful strategies for the development of new drugs against cancer is targeting angiogenesis. In the present study, we found...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181776.
Published: 26 February 2019
... significant infiltration of macrophage antigen-2 (Mac-2) positive macrophages by secreting monocyte chemoattractant protein-1 (MCP-1) at the early stage of suction. Subsequently, these infiltrated macrophages expressed massive vascular endothelial growth factor (VEGF) to promoted angiogenesis. Conclusion: EVE...
Includes: Supplementary data
Articles
Xiao-Fei Liu, Jing-Wei Li, Hong-Zhi Chen, Zi-Yuan Sun, Guang-Xi Shi, Jian-Min Zhu, Ai-Li Song, Ying Wang, Xiang-Qi Li
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181260.
Published: 15 February 2019
...). It has been recently linked to suppress precancerous lesion and tumor development. The current study sought to explore the role of YHD on trans-endothelium and angiogenesis of BC. Methods: HER2+ BC cells were treated with YHD, Trastuzumab, or the combination in vitro and in vivo to compare the effects...
Includes: Supplementary data
Articles
FBXL19-AS1 exerts oncogenic function by sponging miR-431-5p to regulate RAF1 expression in lung cancer
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181804.
Published: 25 January 2019
...Qian Jiang; Li Cheng; Daiyuan Ma; Yanli Zhao Lung cancer is the leading cause of cancer-related mortality worldwide, characterized by uncontrolled proliferation and metastasis of lung cancer cells. Tumor angiogenesis plays a key role in proliferation and metastasis in cancers, and is an essential...
Includes: Supplementary data
Articles
MiRNA-575 suppresses angiogenesis by targeting Rab5-MEK-ERK pathway in endothelial cells
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181218.
Published: 08 January 2019
... as sensitive biomarkers and key regulators in the development of atherosclerosis. However, the biological functions and molecular regulatory mechanisms for miR-575 on angiogenesis remain unknown. In our study, we first identified up-regulation of circulating miR-575 in plasma of essential hypertensive patients...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180882.
Published: 16 November 2018
... License 4.0 (CC BY) . angiogenesis feedback NBAT1 Sox9 Gastric cancer (GC) is one of the most prevalent malignant cancers and the second leading cause of cancer-associated deaths worldwide [ 1 , 2 ]. Due to nonspecific symptoms in the early stage, GC patients are always diagnosed...
Includes: Supplementary data
Articles
Response to comment by Guerra et al.
Open Access
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20181493.
Published: 31 October 2018
... the Creative Commons Attribution License 4.0 (CC BY) . ANGPTL4 angiogenesis inflammation ocular diseases vascular permeability We would like to thank Guerra et al. [ 1 ] for their comments on our article, a review of the multifunctionality of angiopoietin-like 4 in eye disease, highlighting...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180557.
Published: 14 September 2018
...Xinyue Yang; Yan Cheng; Guanfang Su Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine regulating vascular permeability, angiogenesis, and inflammation. Dysregulations in these responses contribute to the pathogenesis of ischemic retinopathies such as diabetic retinopathy (DR), age...
Articles
Specific PKC βII inhibitor: one stone two birds in the treatment of diabetic foot ulcers
Open Access
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20171459.
Published: 07 September 2018
...Sushant Kumar Das; Yi Feng Yuan; Mao Quan Li To explore whether or not inhibition of protein kinase C βII (PKC βII) stimulates angiogenesis as well as prevents excessive NETosis in diabetics thus accelerating wound healing. Streptozotocin (STZ, 60 mg/kg/day for 5 days, i.p.) was injected to induce...
Articles
Zoë E. Clayton, Richard P. Tan, Maria M. Miravet, Katarina Lennartsson, John P. Cooke, Christina A. Bursill, Steven G. Wise, Sanjay Patel
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180563.
Published: 31 July 2018
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . angiogenesis endothelial cells induced pluripotent stem cells wound healing Due to poor circulation and prolonged tissue ischaemia, many patients...
Includes: Supplementary data
Articles
Lingdan Chen, Chunli Liu, Dejun Sun, Tao Wang, Li Zhao, Wenli Chen, Mingjie Yuan, Jian Wang, Wenju Lu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180346.
Published: 03 July 2018
... a higher expression level in the ischemic muscle from diabetic mice when compared with nondiabetic mice. Knockdown of miR-133a using antagomir improved perfusion recovery and angiogenesis in experimental PAD model with diabetes day 21 after HLI. On the other hand, overexpression of miR-133a impaired...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (1): BSR20171455.
Published: 13 February 2018
... been considered to be important for angiogenesis and arteriogenesis after tissue ischemia. This review summarizes the latest clinical and experimental developments of the role of ILs in blood perfusion recovery after PAD. 29 10 2017 02 01 2018 20 01 2018 22 01 2018 © 2018...
Articles
Xin Zhou, Jiajun Chen, Qianren Xiao, Tengyu Wang, Yu Yu, Bo Li, Gaohai Shao, Yunyun Li, Zhongzu Zhang
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (1): BSR20171017.
Published: 19 January 2018
.... Angiogenesis Ewing Sarcoma miR-638 VEGFA To explore the putative role of miR-638 in EWS, the expression of miR-638 was firstly measured using Quanti-Tect SYBR Green PCR Detection System in several EWS cell lines, including A673, SK-ES-1, and RD-ES. Since the bone MSCs were reported...
Articles
Shao-Jung Hsu, Jing-Yi Lee, Te-Yueh Lin, Yu-Hsin Hsieh, Hui-Chun Huang, Fa-Yauh Lee, Han-Chieh Lin, Ming-Chih Hou, Shou-Dong Lee
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171015.
Published: 15 December 2017
... vasodilatation. Angiogenesis also induces increased portal inflow and portosystemic collaterals. The collaterals may induce lethal complications such as gastroesophageal variceal hemorrhage, but the therapeutic effect of vasoconstrictors is still suboptimal due to poor collateral vasoresponsivenss. Curcumin has...
Articles
Pivotal neuroinflammatory and therapeutic role of high mobility group box 1 in ischemic stroke
Open Access
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171104.
Published: 05 December 2017
..., angiogenesis as well as neuroimmunological reactions and post-ischemic brain recovery in IS. We also outline therapeutic roles of HMGB1 in IS. Correspondence: Seidu A. Richard ( [email protected] ) 31 07 2017 29 09 2017 18 10 2017 20 10 2017 © 2017 The Author(s). 2017...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20171062.
Published: 27 October 2017
...Ankit Tiwari; Niharika Pattnaik; Archita Mohanty Jaiswal; Manjusha Dixit Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) is a candidate gene for FSHD. FRG1 regulates various muscle-related functions, but studies have proposed its role in development and angiogenesis also, where...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20170860.
Published: 19 September 2017
... diseases including atherosclerotic vascular disease in coronary, cerebral, and peripheral vessels. Its detrimental effect on vascular system implies the potential application as an inhibitor of angiogenesis. However, the detailed mechanism is unveiled. Inhibitory effect of Hcy was assessed on vascular...
Articles
The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis
Open AccessSeiji Mori, Nobuaki Hatori, Naomasa Kawaguchi, Yoshinosuke Hamada, Tsung-Chieh Shih, Chun-Yi Wu, Kit S. Lam, Nariaki Matsuura, Hirofumi Yamamoto, Yoko K. Takada, Yoshikazu Takada
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (2): BSR20170173.
Published: 10 April 2017
... defective FGF1 mutant (Arg-50 to glutamic acid, R50E) is defective in signalling and antagonistic to FGF1 signalling. R50E suppressed angiogenesis and tumour growth, suggesting that R50E has potential as a therapeutic. However, FGF1 is unstable, and we had to express R50E in cancer cells for xenograft study...
Articles
The angiogenic asset of soft tissue sarcomas: a new tool to discover new therapeutic targets
Open Access
Journal:
Bioscience Reports
Biosci Rep (2014) 34 (6): e00147.
Published: 04 November 2014
...Laura Rocchi; Stefano Caraffi; Roberto Perris; Domenica Mangieri STS (soft tissue sarcomas) are rare malignant tumours deriving from cells of mesenchymal origin and represent only 1% of all malignant neoplasms. It has been extensively demonstrated that angiogenesis has an important role in cancer...
Articles
Journal:
Bioscience Reports
Biosci Rep (2013) 33 (2): e00019.
Published: 01 February 2013
... epithelium-derived factor), a potent inhibitor of tumour angiogenesis, in a model of intracranial gliomas. To assess its potential of tracking gliomas, MSCs (mesenchymal stem cells) were injected into the cerebral hemisphere and it showed that MSCs infiltrated into the vessel beds and scattered throughout...