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Keywords: biomarker
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Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (11): BSR-2018-0668_RET.
Published: 06 November 2024
... to the Journal's queries or the concerns raised. © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarker cervical cancer MCM5 microRNA...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (11): BSR-2021-2446_RET.
Published: 03 November 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Biomarker Immunohistochemistry Osteosarcoma Prognosis Tissue microarray...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (11): BSR20220892.
Published: 25 November 2022
...Zemin Wang; You Ge; Han Li; Gaoqiang Fei; Shuai Wang; Pingmin Wei Currently, the benefits of immune checkpoint inhibitor (ICI) therapy prediction via emerging biomarkers have been identified, and the association between genomic mutation signatures (GMS) and immunotherapy benefits has been widely...
Articles
Yanpeng Ding, Jiayu Fang, Mengge Chen, Yulian Xu, Nuomin Liu, Sha Fang, Wenbin Xiang, Rui Chen, Chaoyan Wu, Haijun Yu
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (10): BSR20221128.
Published: 18 October 2022
... prognostic biomarker for ccRCC and is involved in immune system regulation. Correspondence: Haijun Yu ( [email protected] ) or Chaoyan Wu ( [email protected] ) © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society...
Includes: Supplementary data
Articles
Melvin Khee-Shing Leow, Anantharaj Rengaraj, Kothandaraman Narasimhan, Sanjay K. Verma, Jadegoud Yaligar, Giang Le Thi Thu, Lijuan Sun, Hui Jen Goh, Priya Govindharajulu, Suresh Anand Sadananthan, Navin Michael, Wei Meng, Xavier Gallart-Palau, Lei Sun, Neerja Karnani, Newman Siu Kwan Sze, S. Sendhil Velan
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (5): BSR20212543.
Published: 20 May 2022
.... In the present study, we investigated circulating protein biomarkers that can accurately and reliably reflect BAT activation triggered by cold exposure, capsinoids ingestion and thyroid hormone excess in humans. We discovered an exosomal protein, methylene tetrahydrofolate dehydrogenase (NADP + dependent) 1-like...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20212446.
Published: 11 January 2022
...Tao Guo; Ran Wei; Dylan C. Dean; Francis J. Hornicek; Zhenfeng Duan Background: Although weak SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) expression is a known diagnostic and prognostic biomarker in several malignancies, its expression...
Articles
Nuzhat Sial, Jalil Ur Rehman, Saba Saeed, Mukhtiar Ahmad, Yasir Hameed, Muhammad Atif, Abdul Rehman, Rizwan Asif, Hamad Ahmed, Muhammad Safdar Hussain, Muhammad Rashid Khan, Atifa Ambreen, Ayesha Ambreen
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20211783.
Published: 06 January 2022
... earlier been examined in only a few human cancers. Objectives: Multi-omics profiling of MTHFD1L as a shared biomarker in distinct subtypes of human cancers. Methods: In the current study, for the multi-omics analysis of MTHFD1L in 24 major subtypes of human cancers, a comprehensive in silico approach...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20211096.
Published: 17 December 2021
..., SERPINA1, SCIN , and SLC28A2 ) were identified to correlate with Th17 cells and COAD prognosis, suggesting one new therapy strategy and some predictive biomarkers of COAD. These findings reported by Li et al. may pave one way to explore the molecular mechanism of COAD further. Second, according...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20210908.
Published: 12 October 2021
...Quan Lin; Danli Xie; Liangliang Pan; Yongliang Lou; Mengru Shi Objective: Increasing the efficiency of early diagnosis using noninvasive biomarkers is crucial for enhancing the survival rate of lung cancer patients. We explore the differential expression of non-small cell lung cancer (NSCLC...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (9): BSR20203020.
Published: 03 September 2021
... established novel prognostic biomarkers to predict tamoxifen sensitivity, which may facilitate individualized management of breast cancer. Correspondence: Yujie Zhang ( [email protected] ) 20 09 2020 29 07 2021 17 08 2021 18 08 2021 © 2021 The Author(s). 2021 This is an open...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (8): BSR20203531.
Published: 05 August 2021
...Anze Yu; Kai Guo; Qilin Qin; Changsheng Xing; Xiongbing Zu Background: Evaluation of the feasibility for osteopontin (OPN) to serve as a biomarker in the prognosis and clinical-pathological features of prostate cancer (PCA) patients. Methods: The original publications related to OPN and PCA were...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (5): BSR-20204210_RET.
Published: 04 May 2021
... asthma biomarker blood diagnosis IFN This article is being retracted from Bioscience Reports at the request of the Editorial Board following receipt of a notification from a reader, alerting the Editorial Office to significant similarity with another article, published by different...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (3): BSR20203812.
Published: 19 March 2021
... evidences have revealed that the autophagy process plays a crucial role in the occurrence and progression of various cancers [ 6–9 ]. Several autophagy-related genes (ARGs) were revealed associated with the prognosis of cancer patients and were potential biomarkers for predicting the survival time...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (3): BSR20204210.
Published: 19 March 2021
..., and their combination as biomarker exhibited a good diagnostic capacity for asthma (AUC = 0.832). These findings offered more insight into the underlying mechanism of how IFN signatures affected asthma. The use of the easy-to-apply IFN-related genes might serve as a promising blood-based biomarker for early diagnosis...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20202439.
Published: 17 February 2021
...Zhicheng Wang; Meilin Chen; Yanbing Qiu; Yuqin Yang; Yumei Huang; Xiaoxu Li; Wenling Zhang Tumor immune cell infiltration was significantly correlated with the progression and the effect of immunotherapy in cancers including esophageal carcinoma (ESCA). However, no biomarkers were identified which...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203481.
Published: 27 January 2021
.... The present study aimed to construct regulatory network and seek the potential biomarkers of BC diagnosis and prognosis as well as the molecular therapeutic targets from the perspective of mitochondrial dysfunction. Methods: The microarray data of mitochondria-related encoding genes in BC cell lines were...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203973.
Published: 22 January 2021
...Yexun Song; Wenfang Tang; Hui Li Background: Lung adenocarcinoma (LUAD) is the most frequent histological type of lung cancer, and its incidence has displayed an upward trend in recent years. Nevertheless, little is known regarding effective biomarkers for LUAD. Methods: The robust rank aggregation...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20202042.
Published: 24 November 2020
... biomarkers in BC microenvironment. Correspondence: Shuyuan Zhang ( [email protected] ) * These authors contributed equally to this work. 01 07 2020 05 10 2020 02 11 2020 04 11 2020 © 2020 The Author(s). 2020 This is an open access article published by Portland...
Includes: Supplementary data
Articles
Xue Luo, Xiaolei Zhang, Jianming Peng, Yan Chen, Wenhui Zhao, Xiuling Jiang, Landi Su, Mingqi Xie, Bo Lin
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20200163.
Published: 13 November 2020
..., it is important to find new biomarkers or therapeutic targets in treatment of NSCLC. Methods : The expression levels of miR-371b-5p were detected by qRT-PCR in NSCLC tissues and cell lines. To evaluate the effect of miR-371b-5p on NSCLC progression, we first transfected the miR-371b-5p inhibitor for construction...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20202812.
Published: 28 October 2020
... in cancer stem cells: a promising biomarker and therapeutic target . Stem Cells Transl. Med. 4 , 1033 – 1043 10.5966/sctm.2015-0048 2. Wu G. , Song X. , Liu J. , Li S. , Gao W. , Qiu M. et al . ( 2020 ) Expression of CD44 and the survival in glioma: a meta...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20201590.
Published: 16 September 2020
...Changfeng Man; Yu Fan; Guangli Yin; Jiayu Huang; Jujuan Wang; Hongxia Qiu Circular RNAs (circRNAs) may be potential biomarkers or therapeutic targets of hemophagocytic syndrome (HPS) due to their high stability, covalently closed structure and implicated roles in gene regulation. The aim...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20192436.
Published: 04 September 2020
... biomarkers. Results: A total of 166 DEGs (101 up-regulated and 65 down-regulated) were identified. The up-regulated DEGs were mainly enriched in regulation of the ERK1 and ERK2 cascade, response to interferon-gamma, cell chemotaxis, and migration in biological processes. In the KEGG pathway analysis, up...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20200963.
Published: 20 August 2020
... colorectum tissues, were selected from GSE81558. Correspondence: Li Feng ( [email protected] ) 27 03 2020 13 08 2020 14 08 2020 14 08 2020 bioinformatics biomarker hub genes overall survival primary colorectal cancer Primary colorectal cancer (PCRC...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20194429.
Published: 27 July 2020
...Peilin Shen; Xuejun He; Lin Lan; Yingkai Hong; Mingen Lin Purpose: As bladder cancer (BC) is very heterogeneous and complicated in the genetic level, exploring genes to serve as biomarkers and therapeutic targets is practical. Materials and methods: We searched Gene Expression Omnibus (GEO...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20200902.
Published: 18 June 2020
...) patients. Circular RNA FUNDC1 (circFUNDC1) has been reported to be the diagnosis and prognosis biomarker of AIS. Therefore, the present study aimed to figure out whether circFUNDC1 could be the potential predictor of SAI that could help to guide preventive treatment. In total, 68 patients were included...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20193808.
Published: 03 June 2020
... signature for prognosis prediction in AML may serve as a prognostic biomarker. The three-gene expression prognostic score of the predictive model was calculated as follows: 0.815 * OCT4 + (−0.933) * POU5F1B + (−0.909) * BMI1P1. The coefficients were calculated by Cox regression, and the gene name...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20194448.
Published: 21 April 2020
..., fasting plasma glucose, hs-CRP, TNF-α, white blood cell, RDW,and duration of surgery. P <0.05 was considered as the significant level. biomarker coronary artery bypass grafting postoperative cognitive dysfunction red cell distribution width The red blood cell distribution width (RDW...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20192813.
Published: 15 April 2020
... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . breast cancer biomarker prognosis overall survival The breast carcinoma is one of the world’s most common cancer in women [ 1 ]. The incidence of breast...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20193484.
Published: 27 March 2020
...-486-3p, demonstrating that circRNA_0058063 regulated FOXP4 expression by competitively binding to miR-486-3p. Taken together, circRNA_0058063 functions by sponging miR-486-3p in BC progression, which could act as a new biomarker and further developed to be a therapeutic target in BC...
Articles
Qian-Hui Xu, Pei-Wen Zhu, Biao Li, Wen-Qing Shi, Qi Lin, You-Lan Min, Qian-Min Ge, Qing Yuan, Yi Shao
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194405.
Published: 24 February 2020
... reported to be related not only to the occurrence of liver cancer but also to the causes of some ocular lesions. Purpose A diagnostic standard for the levels of serum biomarkers associated with OM derived from liver cancer in men is urgently needed. Material and methods We examined the association between...
Articles
Wei Liu, Liang-jun Yang, Yuan-liang Liu, Dong-sheng Yuan, Zi-ming Zhao, Qi Wang, Yan Yan, Hua-feng Pan
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20181881.
Published: 24 February 2020
... the Creative Commons Attribution License 4.0 (CC BY) . atrophy biomarker dysplasia H+ K+-ATPase structure-function Warburg effect Correspondence: Hua-feng Pan ( [email protected] ) 17 10 2018 27 11 2019 03 01 2020 06 01 2020 WT mice showed numerous parietal cells...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194067.
Published: 20 February 2020
...Yu Jin; Xing Qin Head and neck squamous cell carcinoma (HNSCC) is ranked as one of the most frequent malignancies worldwide with a high risk of lymph node metastasis, which serves as a main reason for cancer deaths. Identification of the potential biomarkers for lymph node metastasis in HNSCC...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20193678.
Published: 18 February 2020
... the Creative Commons Attribution License 4.0 (CC BY) . The UCSC Xena browser ( http://xena.ucsc.edu/ ) was used to analyze the TCGA Breast Cancer data using the level 3 data. The heatmap and correlation between BIRC5 and CDC20 were then constructed. Biomarker BIRC5 Breast cancer Prognosis...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20193349.
Published: 24 January 2020
... prognostic biomarkers for HNSCC patients. Overall, our study lay a groundwork for further investigation into the underlying molecular mechanisms in HNSCC carcinogenesis, providing potential biomarkers and therapeutic targets for HNSCC. Correspondence: Xing Qin ( [email protected] ) 25 09...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20191251.
Published: 06 January 2020
... various, important roles in osteosarcoma development. The significant 3-lncRNA set could be a novel prediction biomarker that could aid in treatment and also predict the likelihood of recurrence of osteosarcoma in patients. Correspondence: Qingshan Guo ( [email protected] ) or Peng Li...
Includes: Supplementary data
Articles
Chenghan Wu, Hailong Song, Yinzhou Wang, Lili Gao, Yali Cai, Qiong Cheng, Yanru Chen, Zheng Zheng, Yuansheng Liao, Jushan Lin, Buni Xie, Weiwu Cai, Shiju Li, Lianming Liao, Xiaohua Yan
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (11): BSR20182224.
Published: 22 November 2019
... between patients with intracranial aneurysm (IA) and healthy control individuals to evaluate their potential use as biomarkers of IA. Arraystar Human lncRNA Microarray v3.0 was performed to identify differentially expressed lncRNAs and mRNAs in plasma samples (4 ml). lncRNAs with the most pronounced...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (11): BSR20190966.
Published: 12 November 2019
..., particularly concentrating on ischemic heart disease, CH, and cardiac fibrosis. We next discuss the predictive value of lncRNAs as diagnostic biomarkers of CVDs. Correspondence: Bimei Jiang ( [email protected] ) 18 04 2019 03 10 2019 10 10 2019 10 10 2019 © 2019 The Author(s...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (9): BSR20190903.
Published: 13 September 2019
..., and may be a novel biomarker and potential therapeutic target for cervical cancer patients. Correspondence: Fang Yuan ( [email protected] ) * Chun-Ling Yu and Xiao-Ling Xu are co-first authors. 06 04 2019 04 07 2019 14 08 2019 21 08 2019 © 2019 The Author(s...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190884.
Published: 13 August 2019
... 2019 25 07 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarker colorectal cancer KRT18 prognosis...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190095.
Published: 05 August 2019
... biomarker for predicting favorable overall survival in cervical cancer patients. The TP73 expression profiles in cervical cancer tissues ( n =306) and normal cervical tissues ( n =13) were obtained from The Cancer Genome Atlas (TCGA) database ( https://tcga-data.nci.nih.gov ). The prognostic value of TP73...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20191612.
Published: 29 July 2019
.... Therefore, there is an urgent need to have a better understanding of the molecular mechanisms underlying HNSCC progression and to identify essential genes that could serve as effective biomarkers and potential treatment targets. In the present study, original data of three independent datasets were...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190476.
Published: 26 July 2019
... level was significantly up-regulated in NSCLC patients compared with healthy control subjects ( P <0.0001), and the postoperative THBS2 level decreased significantly ( P <0.0001). ROC curves analysis demonstrated that THBS2 was a comparable biomarker as Cyfra21-1 to distinguish early stage NSCLC...
Articles
Si-ying Zhou, Wei Chen, Su-jin Yang, Zi-han Xu, Jia-hua Hu, He-da Zhang, Shan-liang Zhong, Jin-hai Tang
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20190621.
Published: 25 June 2019
... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarker Breast cancer (BCa) circRNA miRNA sponge Breast cancer (BCa) is the most common malignant tumor groups in women worldwide. Approximately 266120 new...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20190166.
Published: 20 June 2019
... 1.4 ± 1.0 1.3 ± 0.9 0.51 Symbol digit test 31.5 ± 10.8 32.4 ± 9.7 0.50 * P <0.05. Postoperative cognitive dysfunction hip fracture malondialdehyde oxidative stress biomarker Postoperative cognitive dysfunction (POCD), a condition that has been poorly...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20181644.
Published: 18 June 2019
... aggressive phenotypes of LSCC by regulating cell proliferation, migration, invasion, apoptosis, and cell cycle, indicating FTH1P3 may serve as a promising therapeutic biomarker for the treatment of LSCC. Correspondence: Yameng Dong ( [email protected] ) 17 09 2018 09 05 2019 22 05 2019...
Articles
Hirono Iriuchishima, Akito Maeshima, Shunsuke Takahashi, Takuma Ishizaki, Akihiko Yokohama, Norifumi Tsukamoto, Takayuki Saitoh, Hirokazu Murakami, Hiroshi Handa
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190206.
Published: 31 May 2019
.... However, no useful biomarkers for early detection of renal damage in MM exist. Reports indicate that activin A, a multifunctional cytokine of the TGF-β superfamily, is involved in the development and progression of various kidney diseases. In the present study, we measured urinary activin A levels...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190602.
Published: 17 May 2019
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarker lncRNA nephroblastoma SOX21-AS1 Wilms tumor Nephroblastoma, also known as Wilms’ tumor, is the most common pediatric kidney cancer accounting for approximately 8% of all malignant tumors in children [ 1...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190667.
Published: 14 May 2019
...Elif Pala; Tuba Denkçeken MicroRNAs (miRNAs) have been proven to play a crucial role in postmenopausal osteoporosis (PMO), and studies on their diagnostic value have been increasing. In our study, we aim to identify the key miRNAs in the PMO that might be potential biomarkers. A comprehensive...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190612.
Published: 03 May 2019
...). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarker large intervening non-coding RNA LSINCT5 osteosarcoma Osteosarcoma is the most frequent...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20182506.
Published: 30 April 2019
... expression was markedly elevated in cervical cancer tissue specimens and cell lines compared with adjacent normal cervical tissue specimens and human normal cervical cell line, respectively. Then, we found high expression of GHET1 is a useful biomarker to discriminate cervical cancer tissues from non...
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