1-50 of 53
Keywords: biomarkers
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biosci Rep (2024) 44 (7): BSR20240249.
Published: 05 July 2024
... the analysis of plasma metabolites carries biomarkers of how obesity and T2D impact post-stroke recovery. Male mice were fed a high-fat diet (HFD) for 10 months leading to development of obesity with T2D or a standard diet (non-diabetic mice). Then, mice were subjected to either transient middle cerebral...
Includes: Supplementary data
Articles
Biosci Rep (2024) 44 (5): BSR-2020-0825_EOC.
Published: 29 April 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarkers non-coding RNA ovarian cancer The Editorial Office has been...
Articles
Biosci Rep (2024) 44 (3): BSR20232063.
Published: 21 March 2024
... BY) . Open access for this article was enabled by the participation of Yale University in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with Individual. biomarkers hepatocellular carcinoma methylation screening...
Articles
Articles
Biosci Rep (2022) 42 (12): BSR20221053.
Published: 09 December 2022
..., this was a systematic analysis to assess the association between sarcomas and levels of pyroptosis-associated genes, and to provide new therapeutic targets and options for sarcomas. biomarkers pyroptosis sacoma Sarcoma is a kind of rare malignancy of mesenchymal tissues [ 1 ]. The disease tends to occur...
Includes: Supplementary data
Articles
Articles
Articles
Biosci Rep (2022) 42 (6): BSR20212516.
Published: 09 June 2022
... biomarkers of Cd-induced renal carcinogenesis, are unclear. In the present study, we established a rat kidney injury model by intragastric administration of Cd to evaluate the morphological and biochemical aspects of kidney injury. We randomly divided Sprague-Dawley rats into control, low Cd (3 mg/kg...
Articles
Biosci Rep (2022) 42 (2): BSR20211248.
Published: 25 February 2022
... in these cellular locations have not been studied in detail yet. In recent years, MMRN1 has been identified as a differentially expressed gene (DEG) in various cancers and it has been proposed as a possible cancer biomarker. Some evidence suggest that MMRN1 expression is regulated by methylation, protein...
Articles
Biosci Rep (2022) 42 (2): BSR20212119.
Published: 18 February 2022
...Xiangpu Wang; Haoyue Xu; Zuo Zhou; Siyuan Guo; Renji Chen Aim: The main of the present study was to investigate the role of insulin-like growth factor 2 mRNA-binding protein 2 ( IGF2BP2 ) in oral squamous cell carcinoma (OSCC) with the overarching of providing new biomarkers or potential...
Includes: Supplementary data
Articles
Biosci Rep (2022) 42 (2): BSR20212304.
Published: 07 February 2022
... methods/therapeutic agents is summarized. In addition, the identification of biomarkers to predict treatment response and the limitations of current ICIs are analyzed, and future directions for ICI treatment are discussed. Correspondence: Wulin Yang ( [email protected] ) * These authors...
Articles
Biosci Rep (2022) 42 (2): BSR20212035.
Published: 04 February 2022
...Yao Song; Meiling Lu; Lijin Feng; Qian Chen; Hua Huang; Qing Lin Breast cancer is a serious malignancy with a high incidence worldwide and a tendency to relapse. We used integrated bioinformatics analysis to identify potential biomarkers in breast carcinoma in the present study. Microarray data...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (12): BSR20212218.
Published: 07 December 2021
.... bioinformatics biomarkers breast cancer master regulators surfaceome transcriptomics While advances in therapeutic options and diagnostic tools have significantly improved breast cancer (BRCA) survival, BRCA incidence has continuously increased over the years, especially in high-income countries [ 1...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (8): BSR20211532.
Published: 20 August 2021
... as the identification of eight protein clusters with motif analysis. Our findings offered an important reference of potential biomarkers and effective therapeutic targets for ACC. Correspondence: Donge Tang ( [email protected] ) or Yong Dai ( [email protected] ) Table 1 Clinical information in OACC tumor...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2021) 41 (7): BSR20211115.
Published: 12 July 2021
... antigen (CEA), the AUC was further improved to 0.874. Conclusion: In the present study, we identified two lncRNAs, UCA1 and PGM5-AS1, in CRC patients’ plasma, which have the potential to be used as diagnostic biomarkers of CRC. Plasma was collected from CRC patients and controls in separating gel...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2021) 41 (7): BSR20210033.
Published: 01 July 2021
...Nese Unver The patterns of chemokine expression play a decisive role in both breast cancer prognosis and metastasis. In a recent article published in Bioscience Reports , ‘Bioinformatics identification of CCL8/21 as potential prognostic biomarkers in breast cancer microenvironment’, Chen et al...
Articles
Biosci Rep (2021) 41 (6): BSR20210344.
Published: 04 June 2021
...Miji Shin; Sora Mun; Sang Hyun Park; Jiyeong Lee; Hee-Gyoo Kang Acute coronary syndrome (ACS) results from inadequate supply of blood flow from the coronary arteries to the heart or ischemia. ACS has an extremely high morbidity and mortality. The levels of biomarkers currently used for detection...
Articles
Biosci Rep (2021) 41 (5): BSR20211016.
Published: 17 May 2021
... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biochemical techniques and resources biomarkers cell cycle genomics molecular basis of health and disease The Biochemical Society is one of the U.K.’s largest single-discipline...
Articles
Biosci Rep (2021) 41 (3): BSR20204394.
Published: 10 March 2021
... Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEGs were performed in the DAVID dataset. Using machine learning, the optimal diagnostic mRNA biomarkers for CC were identified. We used qRT-PCR and Human Protein Atlas (HPA) database to exhibit the differences in gene and protein levels...
Articles
In Collection
Coronavirus
Biosci Rep (2021) 41 (1): BSR20202074.
Published: 29 January 2021
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarkers COVID-19 estrogen immune responses sex-specific The coronavirus infectious disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [ 1–3 ], is a huge...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20202219.
Published: 19 January 2021
..., proteomic analysis was used to identify the differentially expressed proteins (DEPs) and then evaluate the potential plasma biomarkers between CMS and non-CMS groups. A total of 145 DEPs were detected in CMS Han Chinese people who live in the plateau (CMS-HPu), among which 89 were significantly up-regulated...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20203231.
Published: 15 January 2021
... biomarkers hepatocellular carcinoma prognosis TCGA Liver cancer is the sixth most common malignant tumor and the associated mortality rate was ranked fourth among cancer-related deaths in 2018 [ 1 ] and these rates have remained high for nearly 2 years [ 2 ]. Hepatocellular carcinoma (HCC...
Articles
Biosci Rep (2021) 41 (1): BSR20203200.
Published: 08 January 2021
... and validated by the external database, constituting potential prognostic and therapeutic biomarkers for breast cancer subtypes. The functions for the hub genes were evaluated by the database of GeneMANIA ( http://www.genemania.org ) which features several bioinformatics methods: physical interaction...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (12): BSR20202921.
Published: 21 December 2020
...Kecheng Lei; Liwen Zhang; Yijing He; Hui Sun; Weifang Tong; Yichun Xu; Lingjing Jin Early stage diagnosis of Parkinson’s disease (PD) is challenging without significant motor symptoms. The identification of effective molecular biomarkers as a hematological indication of PD may help improve...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (11): BSR20201704.
Published: 23 November 2020
..., it is urgent to investigate the tumor microenvironment in melanoma as well as to identify efficient biomarkers in the diagnosis and treatments of SKCM patients. A comprehensive analysis was performed based on metastatic melanoma samples from the Cancer Genome Atlas (TCGA) database and ESTIMATE algorithm...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20202711.
Published: 06 October 2020
...Jiajia Chen; Rong Wu; Ying Xuan; Min Jiang; Yuecan Zeng Background: Despite the prominent development of medical technology in recent years, the prognosis of non-small cell lung cancer (NSCLC) is still not optimistic. It is crucial to identify more reliable diagnostic biomarkers for the early...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (9): BSR20200141.
Published: 28 September 2020
...Yong Liu; Chao Li; Lijin Dong; Xuewei Chen; Rong Fan Background: Colorectal cancer (CRC) is the third most lethal malignancy in the world, wherein colon adenocarcinoma (COAD) is the most prevalent type of CRC. Exploring biomarkers is important for the diagnosis, treatment, and prevention of COAD...
Articles
Biosci Rep (2020) 40 (7): BSR20200218.
Published: 27 July 2020
... as possible biomarkers for the early diagnosis of patients with ascending TAAs (ATAAs). MiRNA expression was profiled by NanoString nCounter technology using 12 samples including tissue and pre- and post-surgical plasma from ATAA patients. Four miRNAs were selected and further validated by real time...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR20200825.
Published: 24 July 2020
...Fenghua Zhang; Yun Xu; Wenfeng Ye; Jingting Jiang; Changping Wu Background: Ovarian cancer (OC) is one lethal gynecologic cancer, with a 5-year survival rate approximately 47% and localized stage diagnosis of 15%. Circular RNAs are promising biomarkers for malignancies. Methods: CiRS-7 expression...
Articles
Biosci Rep (2020) 40 (5): BSR20191188.
Published: 05 May 2020
....-1329A>G and TP53 c.215C>G (Pro72Arg) SNPs may be risk factors for LSCC. Through this research, we identify two low penetrance genetic variants that may be evaluated as novel biomarkers for this disease, in South American Mestizo populations. Correspondence: Nelson Miguel Varela ( nvarela...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (4): BSR20194512.
Published: 28 April 2020
...Yawei Wang; Haiyan Zhang; Jian Wang; Bei Li; Xiuwen Wang Emerging evidences indicated that exosomal circular RNAs (circRNAs) could serve as diagnostic biomarkers for cancers. However, the expression profiles and clinical significance of circRNAs in lung squamous cell carcinoma (LUSC) remain largely...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (11): BSR20190505.
Published: 15 November 2019
... biomarkers gastric cancer large intervening non-coding RNA The fragments of BCYRN1 containing miR-204-5p binding sites was amplified by PCR and cloned into the pmirGLO luciferase vectors (Promega, Madison, WI, U.S.A.), and named as wt-BCYRN1 and mut-BCYRN1, respectively. Then, GC cells were...
Articles
Biosci Rep (2019) 39 (7): BSR20190770.
Published: 19 July 2019
... 2 ( IGFBP2 ) mRNA in glioblastoma biopsies. The study revealed that patients with high levels of IGFBP2 mRNA had shorter survival and that IGFBP2 transcript level was an independent prognostic factor. It is also of value to determine the prognostic effect of IGFBP2 on established biomarkers...
Articles
Biosci Rep (2019) 39 (5): BSR20190754.
Published: 31 May 2019
... the Creative Commons Attribution License 4.0 (CC BY) . biomarkers cancer FEZF1-AS1 large intervening non-coding RNA retinoblastoma Human retinoblastoma cell lines (Weri-RB-1, Y79 and RBL-13) were grown in Roswell Park Memorial Institute (RPMI)-1640 medium (HyClone, Logan, UT, U.S.A...
Articles
Biosci Rep (2019) 39 (5): BSR20190101.
Published: 17 May 2019
... proliferation, migration and invasion in vitro in gastric cancer. In conclusion, Ecto-5′-nucleotidase is a credible prognostic biomarker, and serves as a potential therapeutic target in gastric cancer. Gastric cancer is the sixth most common cancer worldwide accounting for 1,033,701 newly diagnosed patients...
Articles
Biosci Rep (2019) 39 (5): BSR20190027.
Published: 14 May 2019
.... Currently, serum predictive biomarkers of radioresistance are scare. We enrolled NPC patients, who underwent radiotherapy in the Department of Oncology, Xiangya Hospital, Central Southern University, and analyzed the serum proteins profiles in NPC patients using with quantitative label-free proteomics using...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2019) 39 (4): BSR20190171.
Published: 05 April 2019
... for gastric cancer patient’s overall survival. The study in vitro suggested down-regulation of MIR100HG expression inhibits cell proliferation, migration, and invasion in gastric cancer. In conclusion, MIR100HG is a credible prognostic biomarker and functions as an oncogenic lncRNA in gastric cancer...
Articles
Biosci Rep (2019) 39 (4): BSR20190232.
Published: 02 April 2019
.... Then, immunoblots were visualized by enhanced chemiluminescence (CWBio, Jiangsu, China). Finally, Quantity One Software (Bio-Rad, Hercules, CA, U.S.A.) was used for analyzing the relative integrated density values. β-actin served as the control. biomarkers cancer giloma large intervening non-coding RNA...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (1): BSR20181369.
Published: 18 January 2019
...Xiaohang Hua; Jiangang Chen; Lingli Wu Purpose: Melanosis coli (MC) is a disorder of pigmentation of the wall of the colon, often identified at the time of colonoscopy. The aim of the present study is to identify candidate biomarkers for MC. Methods: The transcriptome data for MC (GSE78933...
Articles
Biosci Rep (2018) 38 (6): BSR20180537.
Published: 14 December 2018
...% CI = 0.21–0.71). In conclusion, NFKB1 rs28362491, NFKBIA rs2233406 and NFKBIA rs696 polymorphisms may serve as biomarkers for predicting risk of AKI in children. Correspondence: Xinqian Zhao ( [email protected] ) 07 04 2018 31 10 2018 06 11 2018 14 11 2018 © 2018...
Articles
Biosci Rep (2018) 38 (5): BSR20180731.
Published: 23 October 2018
... Commons Attribution License 4.0 (CC BY) . biomarkers epigenetics methylation 5-methylcytosine metastasis molecular diagnostics For 45 patients we also analyzed the genomic level of m 5 C in DNA from peripheral blood samples ( Table 1 ). The direct comparison of the amount of m 5 C...
Articles
Biosci Rep (2018) 38 (5): BSR20181187.
Published: 21 September 2018
...Ibtsam Gheith; Abubakr El-Mahmoudy The present study is aimed at utilization of novel and classical kidney function biomarkers to evaluate the nephroprotective potential of Carica papaya leaf extract (CPLE) in gentamicin nephrotoxicity model in albino rats. The used classical biomarkers were urea...
Articles
Biosci Rep (2018) 38 (5): BSR20181039.
Published: 19 September 2018
... Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarkers cancer glioma LINC00675 large intervening non-coding RNA prognosis LINC00675-silenced U-87 and A-172 cells were seeded at a density of 1000 cells per well in 96-well plates. After 1, 2, 3...
Articles
Biosci Rep (2018) 38 (5): BSR20180660.
Published: 07 September 2018
... metabolites may be non-invasive biomarkers for DM and DM-related complications. Different brain regions presented distinct metabolic signatures, indicating region-specific diabetic brain damages. In addition to serving as biomarkers, MRS data on brain metabolites can also shed light on diabetic treatment...
Articles
Biosci Rep (2018) 38 (4): BSR20180525.
Published: 29 August 2018
...Xiaoyi Zhang; Xiaoyan Wang; Jian Wu; Juan Peng; Xin Deng; Yi Shen; Chunjie Yang; Jie Yuan; Yunzeng Zou Few studies have compared the performances of those reported miRNAs as biomarkers for hypertension in a same cohort, we aimed to comprehensively examine the performances of those reported miRNAs...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (3): BSR20180384.
Published: 15 May 2018
... 04 2018 © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AFAP1-AS1 biomarkers large intervening non-coding RNA oncogene...
Articles
Biosci Rep (2018) 38 (1): BSR20171265.
Published: 08 February 2018
... sensitivity and specificity, many studies showed that miR-29a might serve as a potential therapeutic target and promising biomarker in various tumors. In this review, we discussed the functions of miR-29a and its potential application in the diagnosis, treatment and stages of carcinoma, which could provide...