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Keywords: breast cancer
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Articles
Biosci Rep (2021) 41 (12): BSR20212218.
Published: 07 December 2021
... made to characterize the surfaceome of patients with breast cancer, particularly in relation with the current molecular breast cancer (BRCA) classification. In this view, we developed a new computational method to infer cell-surface protein activities from transcriptomics data, termed ‘SURFACER...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (10): BSR20211123.
Published: 19 October 2021
...Ying Jing; Donghai Li MicroRNAs (miRNAs) play important roles in a variety of human diseases, including breast cancer. A number of miRNAs are up- and down-regulated in breast cancer. However, little is known about miRNA similarity and similarity network in breast cancer. Here, a collection of 272...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (8): BSR20211428.
Published: 24 August 2021
...Yen-Jen Chen; Ching-Shui Huang; Nam-Nhut Phan; Tzu-Pin Lu; Chih-Yi Liu; Chi-Jung Huang; Jen-Hwey Chiu; Ling-Ming Tseng; Chi-Cheng Huang Breast cancer intrinsic subtypes have been identified based on the transcription of a predefined gene expression (GE) profiles and algorithm (prediction analysis...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR-2019-0787_RET.
Published: 28 July 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer miR-326 proliferation SOX12 This article is being...
Articles
Biosci Rep (2021) 41 (6): BSR-2018-0571_RET.
Published: 08 June 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer High mobility group AT-hook 2 Invasion microRNA-98...
Articles
Biosci Rep (2021) 41 (4): BSR20210034.
Published: 27 April 2021
.... Radiosensitive gene/biomarker can be useful for predicting which patients would benefit from radiotherapy. The discovery of radiosensitivity biomarkers require multiple pieces of evidence. A prediction model of breast cancer radiosensitivity based on six genes was established. We had put forward some supplements...
Articles
Biosci Rep (2021) 41 (4): BSR-20181859_RET.
Published: 19 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis breast cancer GAS5 miR-221/222 This article is being...
Articles
Biosci Rep (2021) 41 (4): BSR-20201215_EOC.
Published: 09 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ADAM9 breast cancer miR-1298 The Editorial Office has been made aware...
Articles
Biosci Rep (2021) 41 (4): BSR-20192298_EOC.
Published: 07 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer FOXA2 MicroRNA-942 Prognosis Progression The Editorial...
Articles
Biosci Rep (2021) 41 (4): BSR20203391.
Published: 06 April 2021
...Kaichun Li; Qiaoyun Wang; Yanyan Lu; Xiaorong Pan; Long Liu; Shiyu Cheng; Bingxiang Wu; Zongchang Song; Wei Gao Background: The aim of the present study was to confirm the role of Brachyury in breast cancer and to verify whether four types of machine learning models can use Brachyury expression...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (4): BSR-20180738_EOC.
Published: 31 March 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer Casticin invasion MMP-9 PI3K/Akt The Editorial Office...
Articles
Biosci Rep (2021) 41 (1): BSR20203874.
Published: 29 January 2021
...Cui-Cui Zhao; Jing Chen; Li-Ying Zhang; Hong Liu; Chuan-Gui Zhang; Yan Liu Triple negative breast cancer (TNBC) is a more common type of breast cancer with high distant metastasis and poor prognosis. The potential role of lamins in cancer progression has been widely revealed. However, the function...
Articles
Biosci Rep (2021) 41 (1): BSR20202269.
Published: 29 January 2021
... with less survival rate of breast cancer patients. Altogether our study suggests that c.1988+5G<A, R15S, R179L, and A190S SNPs could directly or indirectly destabilize Cyclin D1. Correspondence: Hafiz Muhammad Jafar Hussain ( jafarustc@mail.ustc.edu.cn ) or Ahmed Waqas ( ahmed.waqas@ue.edu.pk...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20203481.
Published: 27 January 2021
...Li-rong Yan; Ang Wang; Zhi Lv; Yuan Yuan; Qian Xu Background: Mitochondria-nuclear cross-talk and mitochondrial retrograde regulation are involved in the genesis and development of breast cancer (BC). Therefore, mitochondria can be regarded as a promising target for BC therapeutic strategies...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (12): BSR20201006.
Published: 14 December 2020
... factor-1α (HIF)-1α and Nur77 have been shown to be involved in the development of breast cancer. However, there is yet no proof of Nur77/HIF-1α involvement in the process of LNT-mediated tumor-inhibition effect. Methods: Immunohistochemistry, immunofluorescence and Hematoxylin–Eosin staining were used...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (12): BSR20201215.
Published: 10 December 2020
... function of miR-1298 in cancers, however, the regulatory mechanism of miR-1298 in breast cancer (BC) remains unclear. Here, our findings showed that miR-1298 was down-regulated in BC tissues and cell lines. Lower level of miR-1298 was significantly correlated with the advanced progression of BC patients...
Articles
Biosci Rep (2020) 40 (12): BSR20202376.
Published: 02 December 2020
...Xing Chen; Junjie Zheng; Min ling Zhuo; Ailong Zhang; Zhenhui You Breast cancer (BRCA) represents the most common malignancy among women worldwide with high mortality. Radiotherapy is a prevalent therapeutic for BRCA that with heterogeneous effectiveness among patients. Here, we proposed to develop...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (11): BSR20200115.
Published: 25 November 2020
... health after NPs exposure. Objective: Green synthesis of gold NPs (AuNPs) and assessment of their activity in 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer mouse model. Methods: Chloroauric acid (HAuCl 4 ) was used in formation of AuNPs with the help of Curcuma longa as aqueous reducing...
Articles
Biosci Rep (2020) 40 (11): BSR20202042.
Published: 24 November 2020
...Bowen Chen; Shuyuan Zhang; Qiuyu Li; Shiting Wu; Han He; Jinbo Huang Background: Breast cancer (BC) is the most common malignancy among females worldwide. The tumor microenvironment usually prevents effective lymphocyte activation and infiltration, and suppresses infiltrating effector cells...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20193271.
Published: 23 October 2020
... in invasive breast cancers and correlates in a mouse orthotopic xenograft model with breast cancer metastasis to bone. However, the underlying cellular mechanisms remain unclear. Here we investigated the function of protein disulphide isomerases in attachment, spreading and migration of three human breast...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (9): BSR-20180571_EOC.
Published: 28 September 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer High mobility group AT-hook 2 Invasion microRNA-98...
Articles
Biosci Rep (2020) 40 (9): BSR20201350.
Published: 24 September 2020
...Wei Wang; Dong Luo; Junlin Chen; Jinyun Chen; Yi Xia; Wenzhi Chen; Yan Wang To investigate the alleviating effects of low-intensity pulsed ultrasound (LIPUS) on myelosuppression of Sprague–Dawley rats with breast cancer induced by cyclophosphamide (CTX). Breast cancer in rats was triggered...
Articles
Biosci Rep (2020) 40 (9): BSR20202537.
Published: 10 September 2020
... of the association between PITX1 expression and the survival in breast cancer remains unclear. Methods: Clinical prognostic parameters and survival data related to PITX1 in breast cancer patients were performed using the bioinformatic analysis including Oncomine, Bc-GenExMiner v4.3, PrognoScan and UCSC Xena. Results...
Articles
Biosci Rep (2020) 40 (9): BSR20201337.
Published: 10 September 2020
...Huayao Zhang; Jingwen Peng; Jianguo Lai; Haiping Liu; Zhiyuan Zhang; Xiangdi Li; Baozhen Liang; Xuejun Chen; Baojia Zou; Siyuan Lin; Lihua Zhang Breast cancer (BC) is a common cancer with poor survival. The present study aimed to explore the effect of miR-940 on the process of BC cells and its...
Articles
Biosci Rep (2020) 40 (8): BSR20202509.
Published: 20 August 2020
...Xialei Yao; Wenwen Wu; Kai Qu; Wei Xi Huaier Granule, a type of traditional Chinese biomedical preparation (TCBP), is considered to be a promising adjuvant therapy for breast cancer. Although an analysis of the published literature has been performed, the exact effects and safety of Huaier Granule...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (8): BSR20200764.
Published: 13 August 2020
...Limei Liu; Jiaomin Yang; Chao Wang Background: Breast cancer (BC) is the most common malignancy in females and remains a main cause of cancer-associated death worldwide. The solute carrier (SLC) groups of membrane transport proteins, which control the influx of zinc, participate in ranging...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (8): BSR20201648.
Published: 11 August 2020
...Min Zhang; Jin Zhang Background: Breast cancer is the second most common malignancy in women and considered as a severe health burden. PEG3 mutations have been observed in several cancers. However, the associations of PEG3 mutation with tumor mutation burden (TMB) and prognosis in breast cancer...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR20201054.
Published: 07 July 2020
...Jun Fang; Feng Chen; Dong Liu; Feiying Gu; Zhigang Chen; Yuezhen Wang Immune checkpoint blockade treatments bring remarkable clinical benefits to fighting several solid malignancies. However, the efficacy of immune checkpoint blockade in breast cancer remains controversial. Several clinical trials...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (6): BSR20200721.
Published: 18 June 2020
...Chaoran Li; Tian Li; Runwei Tang; Shuai Yuan; Weihong Zhang Background: Evidence remains inconsistent regarding the potential influence of β-blocker (BB) use on clinical outcomes in women with breast cancer. We aimed to evaluate the association between BB and prognosis of breast cancer...
Articles
Biosci Rep (2020) 40 (6): BSR20191062.
Published: 17 June 2020
...Jun Liu; Feng Xu; Jie Li; Hongchuan Jiang Objectives: The high mortality of breast cancer (BC) is associated with the strong metastatic properties of primary breast tumor cells. The present study was conducted in order to clarify the effect of Cosmc on the growth and metastasis of BC cell lines...
Articles
Biosci Rep (2020) 40 (5): BSR20201053.
Published: 27 May 2020
...Xinhua Liu; Yonglin Peng; Ju Wang Breast cancer is a common malignant tumor among women whose prognosis is largely determined by the period and accuracy of diagnosis. We here propose to identify a robust DNA methylation-based breast cancer-specific diagnostic signature. Genome-wide DNA methylation...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (5): BSR20191227.
Published: 05 May 2020
... in breast cancer are seldom reported till now, most of which are not systematic and conclusive. The present study was performed to analyze the expression pattern, potential function, and distinct prognostic effect of CDC20 in breast cancer using several online databases including Oncomine, bc-GenExMiner...
Articles
Biosci Rep (2020) 40 (4): BSR20191764.
Published: 23 April 2020
...Chong Lu; Xiuhua Wang; Xiangwang Zhao; Yue Xin; Chunping Liu Breast cancer (BC) poses a great threaten to women health. Numerous evidences suggest the important role of long non-coding RNAs (lncRNAs) in BC development. In the present study, we intended to investigate the role of ARAP1-AS1 in BC...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (4): BSR20192813.
Published: 15 April 2020
... in breast cancer patients with type 2 diabetes mellitus. The present study finally consisted of 428 breast cancer patients with a mean age of 53.0 years. Compared with low TK1 group, the high TK1 group tended to have larger tumor size ( P =0.011) and had more lymph node number ( P =0.021). Significant...
Articles
Biosci Rep (2020) 40 (3): BSR20200164.
Published: 20 March 2020
... that epithelial cells gain migratory property to become mesenchymal cells involved in wound healing, organ fibrosis, and cancer progression. Gremlin-1 (GREM1) is a bone morphogenetic protein antagonist known to play a role in EMT. However, the role of GREM1 in the induction of EMT in human breast cancer cells...
Articles
Biosci Rep (2020) 40 (2): BSR20193678.
Published: 18 February 2020
..., the prognostic significance of BIRC5 remains unclear in breast cancer. Methods: BIRC5 expression and methylation status were evaluated using the Oncomine and The Cancer Genome Atlas (TCGA) databases. The relevance between BIRC5 and different clinicopathological features as well as survival information...
Articles
Biosci Rep (2020) 40 (1): BSR20192465.
Published: 17 January 2020
...-resistant cancer cells; however, the underlying mechanism remains unclear. ERRα was predicted to bind to the serine hydroxymethyltransferase 2 (SHMT2) transcription initiation site in the ER- and HER2-positive cell line BT-474; thus, we hypothesize that ERRα might modulate the resistance of breast cancer...
Articles
Biosci Rep (2020) 40 (1): BSR20192546.
Published: 10 January 2020
...Xiao Chen; Rutaganda Theobard; Jianying Zhang; Xiaofeng Dai RAD50 is commonly depleted in basal-like breast cancer with concomitant absence of INPP4B and several tumor suppressors such as BRCA1 and TP53 . Our previous study revealed that INPP4B and RAD50 interact and such an interaction...
Articles
Biosci Rep (2019) 39 (11): BSR20192298.
Published: 22 November 2019
...Jinku Zhang; Zhiqiang Zhang; Jirui Sun; Qiushuang Ma; Wenming Zhao; Xue Chen; Haizhi Qiao MicroRNA (MiR)-942 regulates the development of a variety of tumors, however, its function in breast cancer (BCa) has been less reported. Therefore, the present study investigated the regulatory effects of miR...
Articles
Biosci Rep (2019) 39 (9): BSR20181853.
Published: 20 September 2019
...Gongling Peng; Zhuohui Zhou; Ming Jiang; Fan Yang Purpose: To identify a subgroup at high risk for loco-regional recurrence (LRR) from T1-2 breast cancer with negative lymph nodes (N0) after mastectomy by using a meta-analysis. Methods and materials: Published studies on the relationship between...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (9): BSR20190230.
Published: 06 September 2019
...Xiping Zhang; Hongjian Yang; Ruiping Zhang Breast cancer (BC) is a malignancy with the highest incidence in women. Great progress has been made in research related to traditional precision medicine for BC. However, many reports have suggested that patients with BC have not benefited a lot from...
Articles
Biosci Rep (2019) 39 (8): BSR20191611.
Published: 23 August 2019
...Liwei Ruan; Xiaojun Qian Background: Breast cancer endangers the life of women and has become the major cause of deaths among them. MiRNAs are found to exert a regulatory effect on the migration, proliferation and apoptosis of breast cancer cells. This research aims at investigating the miR-16-5p...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (7): BSR20190787.
Published: 29 July 2019
... of breast cancer are still unclear. In the present study, we showed that miR-326 was down-regulated in human breast cancer tissues and cell lines. Our results also revealed that miR-326 overexpression significantly suppressed breast cancer cell proliferation, migration and invasion, and induced cell cycle...
Articles
Biosci Rep (2019) 39 (7): BSR20190650.
Published: 16 July 2019
...Hong Dai; Ling-yun Xu; Qi Qian; Qiu-wei Zhu; Wei-xian Chen Resistance to doxorubicin (DOX) is the most common clinical problem in breast cancer therapy, and the underlying molecular mechanism remains to be investigated. MicroRNAs (miRNAs) exhibit important regulatory functions in various malignant...
Articles
Biosci Rep (2019) 39 (7): BSR20190740.
Published: 12 July 2019
...Deshun Yao; Zhiwu Wang; Haifeng Cai; Ying Li; Baosheng Li We retrospectively enrolled 825 breast cancer patients, who was primarily diagnosed in our hospital between January 2009 and December 2014 and explored the relationship between red blood cell distribution width (RDW) and long-term prognosis...
Articles
Biosci Rep (2019) 39 (7): BSR20180551.
Published: 08 July 2019
... been reported to be under-expressed in breast cancer and associated with poor prognosis. However, the exact role of LIFR-AS1 in breast cancer remains largely unclear. The present study aimed to investigate the biological role of LIFR-AS1 in breast cancer and clarify the potential molecular mechanisms...
Articles
Biosci Rep (2019) 39 (6): BSR20190923.
Published: 28 June 2019
...Mingyi Li; Chunpeng Wang; Binbin Yu; Xueyuan Zhang; Fang Shi; Xin Liu Background: Numerous studies reported that RAS-association domain family 1 isoform A ( RASSF1A ) methylation might act as diagnostic biomarker for breast cancer (BC), this meta-analysis aimed to evaluate the value of RASSF1A...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20190436.
Published: 14 June 2019
...Shichao Sun; Yao Sun; Xiaoping Rong; Lei Bai A number of investigations have addressed the importance of high glucose in breast cancer, however, the involvement of angiotensinogen (AGT) in this scenario is yet to be defined. Here we set out to analyze the potential pro-tumor effects of high glucose...
Articles
Biosci Rep (2019) 39 (5): BSR20182079.
Published: 24 May 2019
.... We examined two SNPs rs10877887 and rs13293512 in the promoters of let-7 family to determine if the two SNPs were related to the occurrence of breast cancer (BC). Genotyping of the two SNPs was performed by PCR and restriction fragment length polymorphism analysis or TaqMan assay in 301 BC patients...
Articles
Biosci Rep (2019) 39 (5): BSR20181919.
Published: 17 May 2019
...Rong Xie; Jing Tang; Xianmin Zhu; Hui Jiang Background: Circular RNAs (circRNAs) have been reported as the competing endogenous RNAs (ceRNAs) to sponge microRNAs (miRNAs) implicating in the initiation and progression of breast cancer. However, the functions of circRNAs in breast cancer have...