... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . brown adipose tissue cold adaptation Core body temperature cytokines...

...Naresh C. Bal; Santosh K. Maurya; Sunil Pani; Chinmayee Sethy; Ananya Banerjee; Sarita Das; Srinivas Patnaik; Chanakya N. Kundu There are two well-described thermogenic sites; brown adipose tissue (BAT) and skeletal muscle, which utilize distinct mechanisms of heat production. In BAT, mitochondrial...

... 2017 © 2017 The Author(s). 2017 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adipogenesis appetite brown adipose tissue Capsaicin obesity TRPV1...

...Lars Rebiger; Sigurd Lenzen; Ilir Mehmeti Brown adipose tissue (BAT) cells have a very high oxidative capacity. On the other hand, in obesity and obesity-related diabetes, levels of pro-inflammatory cytokines are elevated, which might promote BAT dysfunction and consequently impair carbohydrate...

...Antonio C. Bianco; Ana Luiza Maia; Wagner Seixas da Silva; Marcelo A. Christoffolete The mechanisms by which thyroid hormone accelerates energy expenditure are poorly understood. In the brown adipose tissue (BAT), activation of thyroid hormone by type 2 iodothyronine deiodinase (D2) has been known...

...Shelagh Wilson BRL 26830 is a thermogenic β -adrenoceptor agonist which stimulates lipolysis and fatty acid oxidation in vivo . It also stimulates insulin secretion, and hence promotes glucose utilisation in vivo . The effect of this agent on white and brown adipose tissue of the rat...

...Gérard Mory; Myriam Gawer; Jean-Claude Kader Chronic cold exposure of rats (9 days at 5°C) induces an alteration of the fatty acid composition of phospholipids in brown adipose tissue. The alteration is due to an increase of the unsaturation degree of these lipids. The phenomenon can be reproduced...

... the effects of TNFα on temperature or VO 2 . Injection of a fragment of TNFα (113–130 amino acid sequence) did not affect body temperature or VO 2 . TNFα injection (icv) significantly increased brown adipose tissue (BAT) in vitro mitochondrial GDP binding, and this effect was slightly inhibited...

...Stewart W. Mercer; Dermot H. Williamson Triacylglycerol/fatty acid substrate cycling was measured in vivo in brown adipose tissue (BAT) and white adipose tissue (WAT) of fed, starved and refed rats. Starvation (24 h) significantly decreased the rate of cycling in BAT, and refeeding chow diet led...

...Mary P. Thompson; Murray R. Grigor A significant diurnal variation in the rates of lipogenesis in vivo in brown adipose tissue occurred in both virgin and lactating rats. On a meal-feeding regime of either a chow, high-sucrose, or high-lipid diet, there was a very large increase in BAT lipogenesis...

... the in vivo content determined from freeze clamped tissue. © 1986 Plenum Publishing Corporation 1986 11 8 1987 rat brown adipocytes brown adipose tissue oxygen consumption ATP content DNA content norepinephrine thermogenesis Bioscience Reports, Vol. 7, No. 8, 1987 Metabolic...

...P. L. Thurlby; S. Wilson; J. R. S. Arch Chronic dietary administration of the oral hypoglycaemic ciglitazone (3 g/day for 14–28 days) to lean, non-diabetic CD1 mice resulted in increased brown adipose tissue mitochondrial GDP binding and a marked increase in the thermic effect of the beta...

...G. Jennings; M. Elia The effects of E. coli endotoxin 0127 B8 on oxygen consumption, temperature, and on the activity of the proton conductance pathway in brown adipose tissue (BAT) were investigated in rats and mice. In rats an increase was observed in rectal and skin temperature, whole body...

... the operation, PCPA-treated rats, either fed ad libitum or pair-fed to the food intake of control rats, showed decreased thermogenic activity and capacity in their interscapular brown adipose tissue (BAT) and also increased fat storage in their white adipose tissue (WAT). These results indicate...

...P. Trayhurn; G. Jennings The effects of fasting and refeeding on the concentration of uncoupling protein in brown adipose tissue mitochondria have been investigated in mice. Fasting mice for 48 h led to a large decrease in the total cytochrome oxidase activity of the interscapular brown fat pad...

...Anders Jacobsson; Jan Nedergaard; Barbara Cannon By the use of an earlier characterised cDNA clone, CIN-1, corresponding to a sequence of the mRNA coding for the brown-fat specific “uncoupling” protein, thermogenin, the amount of thermogenin mRNA found in the brown adipose tissue of mice...

...Francesc Villarroya; Antonio Felipe; Teresa Mampel Hypocaloric diet feeding reduced the mitochondrial protein content and whole tissue GDP-binding in interscapular brown adipose tissue from both virgin and lactating rats. A reduction in brown fat lipoprotein lipase activity was also detected...

...Nancy J. Rothwell; Michael J. Stock 29 11 1985 © 1986 Plenum Publishing Corporation 1986 brown adipose tissue thermogenesis cold diet neural control hormonal control Biosciqnce Reports, Vol. 6, No. 1, 1986 Review Whither Brown Fat? Nancy J. Rothwell 1 and Michael J. Stock...

...Robert G. Ridley; Hasmukh V. Patel; Craig L. J. Parfett; Kimberly A. Olynyk; Susanna Reichling; Karl B. Freeman Poly(A) + RNA was isolated from brown adipose tissue of cold acclimated rats and a fraction enriched for uncoupling protein mRNA was used to generate a cDNA library in pBR 322...