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Keywords: cardiac dysfunction
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Articles

MicroRNA-132 attenuated cardiac fibrosis in myocardial infarction-induced heart failure rats

Open Access
Guoyu Wang, Ruzhu Wang, Zhongbao Ruan, Ling Liu, Yong Li, Li Zhu
Journal: Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20201696.
https://doi.org/10.1042/BSR20201696
Published: 16 September 2020
... heart failure and reduces cardiac fibrosis in MI-induced heart failure is still not well known. The purpose of the present study was to explore the curative effects of miR-132 on cardiac dysfunction and heart fibrosis in rats with MI-induced heart failure. The experiments were performed...
View articletitled, MicroRNA-132 attenuated cardiac fibrosis in myocardial infarction-induced heart failure rats
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Articles

Inhibition of microRNA-146a attenuated heart failure in myocardial infarction rats

Open Access
Junjie He, Ying Lu, Xiaozheng Song, Xiaoxuan Gong, Yong Li
Journal: Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20191732.
https://doi.org/10.1042/BSR20191732
Published: 23 December 2019
... inhibited by miR-146a antagomiR, but aggravated by miR-146a agomiR. These results demonstrated that inhibition of miR-146a improved cardiac dysfunction and cardiac remodeling in heart failure rats. The prevalence of heart failure (HF) continues to rise over time with the aging population [ 1 ]. HF...
View articletitled, Inhibition of microRNA-146a attenuated heart failure in myocardial infarction rats
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