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1-29 of 29
Keywords: cell apoptosis
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Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (8): BSR-2018-2375_RET.
Published: 22 August 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . annulus fibrosus cell apoptosis intervertebral disc degeneration matrix...
Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (8): BSR-2018-1708_RET.
Published: 22 August 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell apoptosis intervertebral disc degeneration nucleus pulposus...
Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (7): BSR-2021-0093_EOC.
Published: 12 July 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . breast cancer cell apoptosis cell proliferation erianin PI3K/Akt pathway...
Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (5): BSR-2020-0485_RET.
Published: 29 May 2024
... the Creative Commons Attribution License 4.0 (CC BY) . acute lymphoblastic leukemia cell apoptosis cell proliferation migration and invasion miR-223 FOXO1 ...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (6): BSR-2017-1082_RET.
Published: 28 June 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ATG9B cell apoptosis clear cell renal cell carcinoma (CCRCC) CRP...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (5): BSR20230041.
Published: 18 May 2023
... intestinal microbes and CRC, the mechanism by which TCM polysaccharides induce CRC cell apoptosis, and how TCM polysaccharides promote immune responses are discussed, as well as TCM polysaccharide use in combination with chemotherapy. TCM polysaccharides provide options for CRC treatment, due...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (4): BSR-2017-1082_EOC.
Published: 06 April 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ATG9B cell apoptosis clear cell renal cell carcinoma CCRCC CRP...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (9): BSR-20180558_RET.
Published: 13 September 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ATM-E2F1 signaling pathway Cell apoptosis Long-non coding RNA ANRIL...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (6): BSR20210093.
Published: 10 June 2021
... at nanomolar level ( Figure 1 A). In addition, typical apoptotic morphology (chromatin condensation and fracture) was detected in MDA-MB-231 cells nucleus treated with 40, 80, or 160 nM erianin for 24 h in DAPI staining, indicating erianin may induce MDA-MB-231 cells apoptosis in a dose-dependent way ( Figure...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (3): BSR-20180558_EOC.
Published: 26 March 2021
... ATM-E2F1 signaling pathway Cell apoptosis Cell proliferation Long-non coding RNA ANRIL Negative feedback regulation Retinoblastoma The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20200485.
Published: 06 October 2020
... proliferation, migration and invasion, but also induced cell apoptosis. Importantly, FOXO1 was a target gene of miR-223 in ALL cells. Silencing of FOXO1 reversed the effects of miR-223 inhibitor on cell proliferation, migration, invasion and apoptosis in ALL. Conclusions: miR-223 could inhibit cell...
Articles
Ching-Chang Lee, Chih-Yen Hsiao, Shan-Chih Lee, Xiao-Fan Huang, Kai-Fu Chang, Ming-Shih Lee, Ming-Chang Hsieh, Nu-Man Tsai
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20202083.
Published: 07 September 2020
... 1 phase and cell apoptosis via the intrinsic and extrinsic apoptosis pathways. JCo combined with 5-FU presented a synergistic effect to reduce cell viability. In conclusion, JCo inhibited oral cancer cell growth by inducing cell cycle arrest and activating cell apoptosis, and JCo significantly...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR-20191845_RET.
Published: 25 June 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gastric adenocarcinoma prognosis microRNA-96-5p cell apoptosis...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20193788.
Published: 03 June 2020
.... The stained cells were observed and photographed under microscope. In addition, integrated optical density (IOD) was used to assess EdU-positive cells with ImageJ software (Bethesda, MD, U.S.A.). High expression of let-7a and TU212 cell apoptosis was analyzed with an Annexin V-FITC apoptosis detection...
Includes: Supplementary data
Articles
Jindong Hao, Chengshun Li, Chao Lin, Yang Hao, Xianfeng Yu, Yidan Xia, Fei Gao, Ziping Jiang, Dongxu Wang
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20192933.
Published: 05 May 2020
... cells. Our results showed that a T–A base transversion had occurred in all cell lines. Moreover, mutation of the regions upstream of the miRNA 675 m 6 A modification site led to reduced expression of H19 and the induction of cell apoptosis in HEK293T cells. To further confirm our results, L02...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20191845.
Published: 15 April 2020
... viability, increased cell apoptosis, and suppressed cell migration and invasion, as well as inhibited the expression of Bcl-2 and COX-2 and promoted Bax, cleaved caspase-3 and cleaved caspase-9 level in MGC-803 cells ( P <0.01). Notably, ZDHHC5 silence reversed the inhibiting effects of miR-96-5p on MGC...
Articles
Mechanism of AMPK-mediated apoptosis of rat gastric smooth muscle cells under high glucose condition
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20192504.
Published: 13 December 2019
... expression was increased, CaMKII activity was decreased in the high glucose-48h group. Under high-glucose condition, activated AMPK can directly or indirectly promote cells apoptosis by regulating the expression and activity of p53, Akt, p70S6K, Protein kinase A (PKA), Phospholipidol C (PLC)-β3, CaMKII...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182109.
Published: 14 May 2019
... of the cell cycle, apoptosis, targets prediction, molecular docking, and alterations in protein levels were performed to elucidate how Tet functions in colon cancer. We found that Tet robustly induced arrest at the G1 phase in colon cancer cell line HT-29. It induced HT-29 cell apoptosis in a dose-dependent...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190456.
Published: 14 May 2019
... in U2OS cells after treatment with hydroxyurea. In addition, hydroxyurea increased cell apoptosis and altered the cell cycle. TET proteins catalyze the oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC); therefore, 5mC and 5hmC levels were evaluated. Increased 5hmC levels were observed...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20182375.
Published: 22 February 2019
.... Control AF cells were cultured without mechanical tension. Cell apoptosis ratio, caspase-3 activity, gene/protein expression of apoptosis-related molecules (Bcl-2, Bax, caspase-3/cleaved caspase-3 and cleaved PARP), matrix macromolecules (aggrecan and collagen I) and matrix metabolism-related enzymes...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181523.
Published: 01 February 2019
...Qingkui Guo; Min Zheng; Ye Xu; Ning Wang; Wen Zhao The present study aims to investigate the mechanism of miR-384 in non-small cell lung cancer (NSCLC) cell apoptosis and autophagy by regulating Collagen α-1(X) chain (COL10A1). Bioinformatics methods were applied to evaluate potential miRNAs...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181369.
Published: 18 January 2019
... with significance. The expression of these screened genes is also related with cell apoptosis. Conclusion: GNG5, LPAR3, MAPK8, and PSMC6 might be candidate biomarkers associated with apoptosis in MC. Correspondence: Lingli Wu ( [email protected] ) 08 08 2018 20 11 2018 03 12 2018 17 12...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181708.
Published: 14 December 2018
... pulposus (NP) region, which obviously promotes NP cell apoptosis. Objective: To study the effects of osteogenic protein-1 (OP-1) on NP cell apoptosis induced by hyperosmolarity and the potential signaling transduction pathway. Methods: Rat NP cells were cultured in a hyperosmotic medium with or without OP...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180558.
Published: 11 December 2018
... radiotherapy, while over the past 2 years, intra-arterial chemotherapy, a novel treatment for retinoblastoma, has been evaluated and appeared to have superior curative effects [ 5 ]. ATM-E2F1 signaling pathway Cell apoptosis Cell proliferation Long-non coding RNA ANRIL Negative feedback regulation...
Articles
Yongxiong He, Bokang Lv, Yanqiang Huan, Bin Liu, Yutang Li, Lizhou Jia, Chenhui Qu, Dongsheng Wang, Hai Yu, Hongwei Yuan
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (1): BSR20171132.
Published: 19 January 2018
... the effect of zhenbao pill on the up-regulation of GPR17 induced by hypoxia, reversed the inhibitory effect of zhenbao pill on the cell apoptosis induced by hypoxia and the recovery of zhenbao pill on hind limb motor function in ASCI rats. Zhenbao pill could inhibit neuronal apoptosis by regulating miR-146a...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171082.
Published: 15 November 2017
.... siRNA and overexpression plasmids construction were used to manipulate the expression of CRP in human CCRCC cell line 786-O. Cell apoptosis and cell cycle progression were determined using flow cytometry (FCM) and Hoechst 33258 staining. CRP expression correlates with ATG9B expression. The expression...
Includes: Supplementary data
Articles
Haiwei Zhang, Fanglin Chen, Yongpeng He, Lin Yi, Chuang Ge, Xiaolong Shi, Chao Tang, Donglin Wang, Yongzhong Wu, Weiqi Nian
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (3): BSR20160478.
Published: 21 June 2017
... 05 2017 11 05 2017 15 05 2017 © 2017 The Author(s). 2017 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cell cycle Cell apoptosis...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (2): BSR20170036.
Published: 28 April 2017
... , but promoted Sp1. High glucose stimulation increased the cell apoptosis and decreased the cell activity, while MIAT suppression reversed the effect induced by high glucose, however, miR-29b knockdown reversed the effects induced by MIAT suppression. Our results provided evidence that the mechanism of cell...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (1): BSR20160479.
Published: 03 February 2017
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell apoptosis cell survival hypoxia lymphocyte mammalian target of rapamycin In mammalian cells, energy metabolism needs to be precisely regulated [ 1 ]. Under different conditions, cells may rely on different...