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Biosci Rep (2020) 40 (9): BSR20201350.
Published: 24 September 2020
... factor-β, and intercellular cell adhesion molecule-1, meanwhile LIPUS will decrease the expression of interleukin-6, tumor necrosis factor-α, and vascular cell adhesion molecule-1. LIPUS has potential to be a new adjuvant therapy method in clinic for ameliorating chemotherapy-induced myelosuppression...
Biosci Rep (2020) 40 (9): BSR20200935.
Published: 02 September 2020
... Commons Attribution License 4.0 (CC BY) . chemotherapy Colon cancer Irinotecan PHY906 traditional Chinese Medicine Colon cancer is a common malignant tumor and the second leading cause of mortality worldwide in 2018 [ 1 ]. With the improvement in people’s living standards and changes in...
Includes: Supplementary data
Biosci Rep (2020) 40 (6): BSR20200097.
Published: 17 June 2020
...Tong Qin; Hongmian Zhao; Yunli Shao; Ning Hu; Jinlong Shi; Lin Fu; Yijie Zhang The purpose of the present study was to investigate whether expression levels of adenylate kinase 1 (AK1) were associated with prognosis of acute myeloid leukemia (AML) in patients treated with chemotherapy or allogeneic...
Biosci Rep (2020) 40 (5): BSR20192347.
Published: 07 May 2020
... hypophysitis. Conclusions: ICI therapy was safer than chemotherapy, especially ICI monotherapy such as anti-PD-1 antibodies in NSCLC. Compared with standard treatments, ICI drugs increased the risk of organ-specific IRAEs, although the overall incidence remained low. Correspondence: Weimin Li ( weimi003...
Includes: Supplementary data
Biosci Rep (2019) 39 (7): BSR20190378.
Published: 16 July 2019
... License 4.0 (CC BY) . chemotherapy cytotoxicity nucleotide excision repairn ruthenium XPA XPC Ruthenium compounds are an attractive and actively researched alternative to platinum-based chemotherapeutics. Previous studies indicate a wide range of potential biological activities of...
Biosci Rep (2019) 39 (6): BSR20190052.
Published: 28 June 2019
...Bin Ke; Xinlin Wu; Qiong Yang; Yuanyuan Huang; Fang Wang; Yuxin Gong; Junfang Liu; Lin Shi Traditional Chinese Medicine (TCM) has been recognized to be conducive to enhancing the efficiency and reducing the side effects in the whole course of cancer treatment. The mechanisms of TCM/chemotherapy...
Biosci Rep (2018) 38 (5): BSR20180790.
Published: 21 September 2018
...-related LncRNA and up-regulated in many cancers for tumor growth and metastasis, but its role in chemotherapy resistance is unclear. We here investigated the function of LINC00473 in colorectal cancer (CRC) in vitro and in vivo . The CRC tissues ( n =20) and relative normal tissues were collected and...
Biosci Rep (2018) 38 (4): BSR20180704.
Published: 06 July 2018
... observations suggest that MIAT plays an important role in breast tumorigenesis. Strategies to decrease MIAT expression levels may improve sensitivity to therapy in breast cancer by enhancing the apoptotic responses to conventional chemotherapies. Apoptosis Breast Cancer Chemotherapy MIAT OCT4...
Biosci Rep (2017) 37 (2): BSR20160445.
Published: 27 March 2017
...Na Li; Wei Zhang Recently, autophagy has been indicated to play an essential role in various biological events, such as the response of cervical cancer cells to chemotherapy. However, the exact signalling mechanism that regulates autophagy during chemotherapy remains unclear. In the present study...
Biosci Rep (2015) 35 (4): e00225.
Published: 14 July 2015
...Christina Peters; Stuart Brown Over the past couple of decades, antibody–drug conjugates (ADCs) have revolutionized the field of cancer chemotherapy. Unlike conventional treatments that damage healthy tissues upon dose escalation, ADCs utilize monoclonal antibodies (mAbs) to specifically bind...
Biosci Rep (2014) 34 (6): e00168.
Published: 23 December 2014
... enzyme and is implicated in resistance of tumours to antimetabolite chemotherapy. chemotherapy translation regulation UV cross-linking X-ray crystallography 1 Present address: Merck & Co, Palo Alto, CA, U.S.A. 2 To whom correspondence should be addressed (email tch...
Biosci Rep (2001) 21 (3): 353–359.
Published: 01 June 2001
... Antimalarials chemotherapy free radicals lipid peroxidation malaria oxidants Bioscience Reports, Vol. 21, No. 3, June 2001 ( 2001) Antimalarial Drugs Exacerbate Rat Liver Microsomal Lipid Peroxidation in the Presence of Oxidants E. Olatunde Farombi,1,2 Stanley Adoro,1 and Samuel Uhunmwangho1 Receiûed...
Biosci Rep (1989) 9 (5): 509–529.
Published: 01 October 1989
... Gertrude B. Elion and published in Les Prix Nobel 1988, printed in Sweden by Norstedts Tryckeri, Stockholm, Sweden, 1989, republished here with the permission of the Nobel Foundation, the copyright holder. © 1989 Plenum Publishing Corporation 1989 purine antimetabolite chemotherapy anti...