...Nicola E. Owen; Thomas L. Williams; Janet J. Maguire; Rhoda E. Kuc; Emma E. Davenport; Anthony P. Davenport High blood pressure in the portal vein, portal hypertension (PH), is the final common pathway in liver cirrhosis regardless of aetiology. Complications from PH are the major cause...

...Xiaoli Wu; Daofu Zhang; Yuexiao Yu; Lianqing Lou; Xiaofei Li Background: Proton pump inhibitor (PPI) is commonly used in patients with cirrhosis. However, some studies demonstrated that PPI use was associated with adverse outcome in patients with cirrhosis. We aimed to perform a meta-analysis...

... requiring RRT in the multivariate analysis ( Table 4 ). acute kidney injury cirrhosis renal replacement Transplantation Patients following orthotopic liver transplantation (OLT) are at major risk to develop acute kidney injury (AKI) [ 1–4 ]. Factors that may contribute to postoperative AKI...

... for non-invasive diagnosis and secondly to provide a platform for experimental therapies aiming to inhibit intrahepatic neutrophil migration. 111 In-leucocyte scintigraphy was performed 30 min and 24 h post-injection in 19 patients with SAH, 14 abstinent patients with alcohol-related cirrhosis and 11...

...Imran Haq; James A. Irving; Sarah V. Faull; Jennifer A. Dickens; Adriana Ordóñez; Didier Belorgey; Bibek Gooptu; David A. Lomas The common severe Z mutation (E342K) of α 1 -antitrypsin forms intracellular polymers that are associated with liver cirrhosis. The native fold of this protein is well...