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Retraction: MIR600HG suppresses metastasis and enhances oxaliplatin chemosensitivity by targeting ALDH1A3 in colorectal cancer

Biosci Rep (2024) 44 (9): BSR-2020-0390_RET.

https://doi.org/10.1042/BSR-2020-0390_RET

Published: 10 September 2024

... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ALDH1A3 Chemosensitivity colorectal cancer Metastasis MIR600HG...

View articletitled, Retraction: MIR600HG suppresses metastasis and enhances oxaliplatin chemosensitivity by targeting ALDH1A3 in colorectal cancer

Articles

Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells

Laiyen Garcia Delgado, Amélie Derome, Samantha Longpré, Marilyne Giroux-Dansereau, Ghenwa Basbous, Christine Lavoie, Caroline Saucier, Jean-Bernard Denault

Biosci Rep (2024) 44 (6): BSR20240182.

https://doi.org/10.1042/BSR20240182

Published: 21 June 2024

.... Specifically, strong evidence points to the involvement of sorting nexins (SNXs), particularly SNX1 and SNX2, in the signaling and trafficking of the receptor tyrosine kinase (RTK) MET in colorectal cancer (CRC). Activation of hepatocyte growth factor (HGF) receptor MET is a key driver of CRC progression...

View articletitled, Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells

Includes: Supplementary data

Articles

Parvimonas micra infection enhances proliferation, wound healing, and inflammation of a colorectal cancer cell line

Muhammad Nur Adam Hatta, Ezanee Azlina Mohamad Hanif, Siok-Fong Chin, Teck Yew Low, Hui-min Neoh

Biosci Rep (2023) 43 (6): BSR20230609.

https://doi.org/10.1042/BSR20230609

Published: 13 June 2023

...Muhammad Nur Adam Hatta; Ezanee Azlina Mohamad Hanif; Siok-Fong Chin; Teck Yew Low; Hui-min Neoh The gut microbiota Parvimonas micra has been found to be enriched in gut mucosal tissues and fecal samples of colorectal cancer (CRC) patients compared with non-CRC controls. In the present study, we...

View articletitled, Parvimonas micra infection enhances proliferation, wound healing, and inflammation of a colorectal cancer cell line

Articles

Polysaccharides from Chinese herbs as natural weapons against colorectal cancer

Mingyue Zhou, Yinzi Yue, Yahui Wang, Shuai Yan

Biosci Rep (2023) 43 (5): BSR20230041.

https://doi.org/10.1042/BSR20230041

Published: 18 May 2023

...Mingyue Zhou; Yinzi Yue; Yahui Wang; Shuai Yan Colorectal cancer (CRC) ranks third and second among the most widespread cancers worldwide and the most common causes of human death due to cancer, respectively. Furthermore, for unknown reasons, numbers of young patients diagnosed with colon cancer...

View articletitled, Polysaccharides from Chinese herbs as natural weapons against colorectal cancer

Includes: Supplementary data

Articles

Retraction: MicroRNA-208a-3p functions as an oncogene in colorectal cancer by targeting PDCD4

Biosci Rep (2022) 42 (12): BSR-2018-1598_RET.

https://doi.org/10.1042/BSR-2018-1598_RET

Published: 22 December 2022

... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Colorectal cancer micrRNA-208-3p PDCD4 This article is being retracted...

View articletitled, Retraction: MicroRNA-208a-3p functions as an oncogene in colorectal cancer by targeting PDCD4

Articles

Expression of Concern: MicroRNA-208a-3p functions as an oncogene in colorectal cancer by targeting PDCD4

Biosci Rep (2022) 42 (11): BSR-2018-1598_EOC.

https://doi.org/10.1042/BSR-2018-1598_EOC

Published: 10 November 2022

View articletitled, Expression of Concern: MicroRNA-208a-3p functions as an oncogene in colorectal cancer by targeting PDCD4

Articles

A robust immune-related lncRNA signature for the prognosis of human colorectal cancer

Gongmin Zhu, Lijiao Pei, Fan Yang, Chenliang Zhang

Biosci Rep (2022) 42 (7): BSR20220078.

https://doi.org/10.1042/BSR20220078

Published: 20 July 2022

...Gongmin Zhu; Lijiao Pei; Fan Yang; Chenliang Zhang Background: Colorectal cancer (CRC) is one of the most prevalent malignant cancers worldwide. Immune-related long non-coding RNAs (IRlncRNAs) are proved to be essential in the development and progression of carcinoma. The purpose of the present...

View articletitled, A robust immune-related lncRNA signature for the prognosis of human colorectal cancer

Articles

PUNISHER rs12318065 C>A transversion: a putative somatic driver mutation for poor prognosis in colon cancer

Sameerah Shaheen, Eida M. Alshammari, Sara H. Mokhtar, Aliah R. Alshanwani, Eman A. Toraih, Afaf T. Ibrahiem, Manal S. Fawzy, Shymaa Ahmed Maher

Biosci Rep (2022) 42 (6): BSR20220465.

https://doi.org/10.1042/BSR20220465

Published: 27 June 2022

... BY) . colorectal cancer Prognosis PUNISHER rs12318065 single nucleotide polymorphisms survival The present samples included 138 adenocarcinomas (67.6%), 30 mucinous (14.7%), 26 signet ring cells (12.7%), and 10 undifferentiated (4.9%) carcinoma cases. For all samples, the original hematoxylin...

View articletitled, PUNISHER rs12318065 C>A transversion: a putative somatic driver mutation for poor prognosis in colon cancer

Articles

Lipocalin 2 potentially contributes to tumorigenesis from colitis via IL-6/STAT3/NF-κB signaling pathway

Se Lim Kim, Min Woo Shin, Seung Young Seo, Sang Wook Kim

Biosci Rep (2022) 42 (5): BSR20212418.

https://doi.org/10.1042/BSR20212418

Published: 13 May 2022

... the functional role and mechanisms of LCN2 in tumorigenesis using murine colitis-associated cancer (CAC) models and human colorectal cancer (CRC) cells. Using murine CAC models, we found that LCN2 was preferentially expressed in colonic tissues from CAC models compared with tissues from normal mice. In vitro...

View articletitled, Lipocalin 2 potentially contributes to tumorigenesis from colitis via IL-6/STAT3/NF-κB signaling pathway

Articles

Correction: Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT pathway

Biosci Rep (2022) 42 (1): BSR-2019-0249_COR.

https://doi.org/10.1042/BSR-2019-0249_COR

Published: 18 January 2022

... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . 5-fluorouracil colorectal cancer MicroRNA-543 PTEN The authors of the original article “Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT...

View articletitled, Correction: Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT pathway

Articles

Capturing tumour heterogeneity in pre- and post-chemotherapy colorectal cancer ascites-derived cells using single-cell RNA-sequencing

Tiraput Poonpanichakul, Meng-Shin Shiao, Natnicha Jiravejchakul, Ponpan Matangkasombut, Ekaphop Sirachainan, Varodom Charoensawan, Natini Jinawath

Biosci Rep (2021) 41 (12): BSR20212093.

https://doi.org/10.1042/BSR20212093

Published: 07 December 2021

... colorectal cancer (CRC). Cancer cells in ascites reflect poor prognosis and serve as a good specimen to study tumour heterogeneity, as they represent a collection of multiple metastatic sites in the peritoneum. In the present study, we have employed single-cell RNA-sequencing (scRNA-seq) to explore...

View articletitled, Capturing tumour heterogeneity in pre- and post-chemotherapy colorectal cancer ascites-derived cells using single-cell RNA-sequencing

Includes: Supplementary data

Articles

A novel prognostic immunoscore based on The Cancer Genome Atlas to predict overall survival in colorectal cancer patients

Zuxiong Tang, Yufan Wu, Ding Sun, Xiaofeng Xue, Lei Qin

Biosci Rep (2021) 41 (10): BSR20210039.

https://doi.org/10.1042/BSR20210039

Published: 19 October 2021

...Zuxiong Tang; Yufan Wu; Ding Sun; Xiaofeng Xue; Lei Qin Colorectal cancer (CRC) is highly prevalent worldwide. The relationship between the infiltration of immunocytes in CRC and clinical outcome has been investigated in recent years. The present study aims to construct a new prognostic signature...

View articletitled, A novel prognostic immunoscore based on The Cancer Genome Atlas to predict overall survival in colorectal cancer patients

Includes: Supplementary data

Articles

Identification of hub genes in colorectal cancer based on weighted gene co-expression network analysis and clinical data from The Cancer Genome Atlas

Yu Zhang, Jia Luo, Zhe Liu, Xudong Liu, Ying Ma, Bohang Zhang, Yuxuan Chen, Xiaofeng Li, Zhiguo Feng, Ningning Yang, Dayun Feng, Lei Wang, Xinqiang Song

Biosci Rep (2021) 41 (7): BSR20211280.

https://doi.org/10.1042/BSR20211280

Published: 26 July 2021

...Yu Zhang; Jia Luo; Zhe Liu; Xudong Liu; Ying Ma; Bohang Zhang; Yuxuan Chen; Xiaofeng Li; Zhiguo Feng; Ningning Yang; Dayun Feng; Lei Wang; Xinqiang Song Colorectal cancer (CRC) is one of the most common tumors worldwide and is associated with high mortality. Here we performed bioinformatics...

View articletitled, Identification of hub genes in colorectal cancer based on weighted gene co-expression network analysis and clinical data from The Cancer Genome Atlas

Includes: Supplementary data

Articles

Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer

Katie J. Stott, Bethan Phillips, Lee Parry, Stephanie May

Biosci Rep (2021) 41 (7): BSR20204113.

https://doi.org/10.1042/BSR20204113

Published: 26 July 2021

... there is no defined consensus on the composition of a healthy microbiome due to confounding factors such as ethnicity, geographical locations, age and sex, there are undoubtably populations of microbes that are consistently dysregulated in gut diseases including colorectal cancer (CRC). In this review, we discuss...

View articletitled, Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer

Articles

Correction: Systematic identification of celastrol-binding proteins reveals that Shoc2 is inhibited by celastrol

Biosci Rep (2021) 41 (4): BSR-20181233_COR.

https://doi.org/10.1042/BSR-20181233_COR

Published: 27 April 2021

... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Celastrol Colorectal cancer ERK Human proteome microarray Shoc2...

View articletitled, Correction: Systematic identification of celastrol-binding proteins reveals that Shoc2 is inhibited by celastrol

Articles

Association analysis of miRNA-related genetic polymorphisms in miR-143/145 and KRAS with colorectal cancer susceptibility and survival

Danyang Wang, Qingmin Liu, Yanjun Ren, Yan Zhang, Xin Wang, Bing Liu

Biosci Rep (2021) 41 (4): BSR20204136.

https://doi.org/10.1042/BSR20204136

Published: 22 April 2021

...Danyang Wang; Qingmin Liu; Yanjun Ren; Yan Zhang; Xin Wang; Bing Liu Background: There is accumulating evidence of aberrant expression of miR-143 and miR-145 and their target gene KRAS in colorectal cancer (CRC). We hypothesize that single nucleotide polymorphisms (SNPs) within or near mRNA...

View articletitled, Association analysis of miRNA-related genetic polymorphisms in miR-143/145 and KRAS with colorectal cancer susceptibility and survival

Includes: Supplementary data

Articles

Expression of Concern: MiR-106b-5p Regulates the Migration and Invasion of Colorectal Cancer Cells by Targeting FAT4

Biosci Rep (2021) 41 (4): BSR-20200098_EOC.

https://doi.org/10.1042/BSR-20200098_EOC

Published: 07 April 2021

... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Colorectal cancer FAT4 MicroRNA-106b-5p ...

View articletitled, Expression of Concern: MiR-106b-5p Regulates the Migration and Invasion of Colorectal Cancer Cells by Targeting FAT4

Articles

Expression of Concern: Long non coding RNA FAM3D-AS1 inhibits development of colorectal cancer through NF-kB signaling pathway

Biosci Rep (2021) 41 (4): BSR-20190724_EOC.

https://doi.org/10.1042/BSR-20190724_EOC

Published: 07 April 2021

... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Colorectal cancer EMT lncRNA The Editorial Office has been made aware...

View articletitled, Expression of Concern: Long non coding RNA FAM3D-AS1 inhibits development of colorectal cancer through NF-kB signaling pathway

Articles

Lipid profiling of mouse intestinal organoids for studying APC mutations

Zoë Jukes, Anne Freier, Maria Glymenaki, Richard Brown, Lee Parry, Elizabeth Want, Panagiotis A. Vorkas, Jia V. Li

Biosci Rep (2021) 41 (3): BSR20202915.

https://doi.org/10.1042/BSR20202915

Published: 17 March 2021

...Zoë Jukes; Anne Freier; Maria Glymenaki; Richard Brown; Lee Parry; Elizabeth Want; Panagiotis A. Vorkas; Jia V. Li Inactivating mutations including both germline and somatic mutations in the adenomatous polyposis coli ( APC ) gene drives most familial and sporadic colorectal cancers. Understanding...

View articletitled, Lipid profiling of mouse intestinal organoids for studying APC mutations

Includes: Supplementary data

Articles

Stool DNA test targeting methylated syndecan-2 (SDC2) as a noninvasive screening method for colorectal cancer

Wei-Chih Su, Wei-Yu Kao, Tsung-Kun Chang, Hsiang-Lin Tsai, Ching-Wen Huang, Yen-Cheng Chen, Ching-Chun Li, Yi-Chien Hsieh, Hsing-Jung Yeh, Chun-Chao Chang, Jaw-Yuan Wang

Biosci Rep (2021) 41 (1): BSR20201930.

https://doi.org/10.1042/BSR20201930

Published: 14 January 2021

...Wei-Chih Su; Wei-Yu Kao; Tsung-Kun Chang; Hsiang-Lin Tsai; Ching-Wen Huang; Yen-Cheng Chen; Ching-Chun Li; Yi-Chien Hsieh; Hsing-Jung Yeh; Chun-Chao Chang; Jaw-Yuan Wang Despite the steadily increasing worldwide incidence of colorectal cancer (CRC), an effective noninvasive approach for early...

View articletitled, Stool DNA test targeting methylated syndecan-2 (SDC2) as a noninvasive screening method for colorectal cancer

Includes: Supplementary data

Articles

Lack of association between miR-146a rs2910164 C/G locus and colorectal cancer: from a case–control study to a meta-analysis

Jiakai Jiang, Sheng Zhang, Weifeng Tang, Zhiyuan Qiu

Biosci Rep (2021) 41 (1): BSR20191729.

https://doi.org/10.1042/BSR20191729

Published: 04 January 2021

...Jiakai Jiang; Sheng Zhang; Weifeng Tang; Zhiyuan Qiu Previous studies suggested that miR-146a rs2910164 (C/G) locus was predicted to influence the risk of cancer. However, the relationship of miR-146a rs2910164 locus with colorectal cancer (CRC) susceptibility was controversial. We recruited 1003...

View articletitled, Lack of association between miR-146a rs2910164 C/G locus and colorectal cancer: from a case–control study to a meta-analysis

Includes: Supplementary data

Articles

MiR-106b-5p regulates the migration and invasion of colorectal cancer cells by targeting FAT4

Min Pan, Qiuqiu Chen, Yusong Lu, Feifei Wei, Chunqiao Chen, Guiyan Tang, Hui Huang

Biosci Rep (2020) 40 (11): BSR20200098.

https://doi.org/10.1042/BSR20200098

Published: 02 November 2020

...Min Pan; Qiuqiu Chen; Yusong Lu; Feifei Wei; Chunqiao Chen; Guiyan Tang; Hui Huang MicroRNA-106b-5p (miR-106b-5p) is involved in the development of many cancers including colorectal cancer (CRC), and FAT4 is correlated with regulation of growth and apoptosis of cancer cells. The present study aimed...

View articletitled, MiR-106b-5p regulates the migration and invasion of colorectal cancer cells by targeting FAT4

Articles

Association of UGT1A1*6 polymorphism with irinotecan-based chemotherapy reaction in colorectal cancer patients: a systematic review and a meta-analysis

Xiaoyun Zhu, Ruchao Ma, Xin Ma, Gang Yang

Biosci Rep (2020) 40 (10): BSR20200576.

https://doi.org/10.1042/BSR20200576

Published: 21 October 2020

...Xiaoyun Zhu; Ruchao Ma; Xin Ma; Gang Yang Colorectal cancer (CRC) is a leading cause of cancer-related deaths across the world. Irinotecan (IRI) is commonly used to treat CRC, and IRI-based chemotherapy is linked with adverse reaction and the efficacy of the treatment regimen. The gene UGT1A1 plays...

View articletitled, Association of UGT1A1*6 polymorphism with irinotecan-based chemotherapy reaction in colorectal cancer patients: a systematic review and a meta-analysis

Articles

Detection of genes responsible for cetuximab sensitization in colorectal cancer cells using CRISPR-Cas9

Ting-ting Hu, Jia-wen Yang, Ye Yan, Ying-ying Chen, Hai-bo Xue, You-qun Xiang, Le-chi Ye

Biosci Rep (2020) 40 (10): BSR20201125.

https://doi.org/10.1042/BSR20201125

Published: 21 October 2020

...Ting-ting Hu; Jia-wen Yang; Ye Yan; Ying-ying Chen; Hai-bo Xue; You-qun Xiang; Le-chi Ye Colorectal cancer (CRC) is a common malignant tumor in digestive tract with highly invasive and metastatic capacity. Drug sensitivity remains a significant obstacle to successful chemotherapy in CRC patients...

View articletitled, Detection of genes responsible for cetuximab sensitization in colorectal cancer cells using CRISPR-Cas9

Articles

Identification and verification of three key genes associated with survival and prognosis of COAD patients via integrated bioinformatics analysis

Yong Liu, Chao Li, Lijin Dong, Xuewei Chen, Rong Fan

Biosci Rep (2020) 40 (9): BSR20200141.

https://doi.org/10.1042/BSR20200141

Published: 28 September 2020

...Yong Liu; Chao Li; Lijin Dong; Xuewei Chen; Rong Fan Background: Colorectal cancer (CRC) is the third most lethal malignancy in the world, wherein colon adenocarcinoma (COAD) is the most prevalent type of CRC. Exploring biomarkers is important for the diagnosis, treatment, and prevention of COAD...

View articletitled, Identification and verification of three key genes associated with survival and prognosis of COAD patients via integrated bioinformatics analysis

Articles

Identification of key gene modules and genes in colorectal cancer by co-expression analysis weighted gene co-expression network analysis

Peng Wang, Huaixin Zheng, Jiayu Zhang, Yashu Wang, Pingping Liu, Xiaoyan Xuan, Qianru Li, Ying Du

Biosci Rep (2020) 40 (9): BSR20202044.

https://doi.org/10.1042/BSR20202044

Published: 01 September 2020

...Peng Wang; Huaixin Zheng; Jiayu Zhang; Yashu Wang; Pingping Liu; Xiaoyan Xuan; Qianru Li; Ying Du Colorectal cancer (CRC) has been one of the most common malignancies worldwide, which tends to get worse for the growth and aging of the population and westernized lifestyle. However...

View articletitled, Identification of key gene modules and genes in colorectal cancer by co-expression analysis weighted gene co-expression network analysis

Articles

Individual and combined effects of GSTM1 and GSTT1 polymorphisms on colorectal cancer risk: an updated meta-analysis

Liang Song, Chen Yang, Xiao-Feng He

Biosci Rep (2020) 40 (8): BSR20201927.

https://doi.org/10.1042/BSR20201927

Published: 25 August 2020

...Liang Song; Chen Yang; Xiao-Feng He Background. The presence or absence of glutathione S-transferase M1 gene ( GSTM1 ) and glutathione S-transferase T1 gene ( GSTT1 ) polymorphisms, and their combined effects have been suggested as a risk factor for colorectal cancer (CRC). However, the results...

View articletitled, Individual and combined effects of GSTM1 and GSTT1 polymorphisms on colorectal cancer risk: an updated meta-analysis

Articles

Low circulating 25-hydroxyvitamin D level is associated with increased colorectal cancer mortality: a systematic review and dose–response meta-analysis

Guanghai Wu, Mei Xue, Yongjie Zhao, Youkui Han, Shuai Zhang, Judong Zhang, Chao Li, Jing Xu

Biosci Rep (2020) 40 (7): BSR20201008.

https://doi.org/10.1042/BSR20201008

Published: 29 July 2020

...Guanghai Wu; Mei Xue; Yongjie Zhao; Youkui Han; Shuai Zhang; Judong Zhang; Chao Li; Jing Xu Epidemiological studies have suggested inconclusive associations between 25-hydroxyvitamin D (25(OH)D) and survival in patients with colorectal cancer (CRC). The aim of the present study...

View articletitled, Low circulating 25-hydroxyvitamin D level is associated with increased colorectal cancer mortality: a systematic review and dose–response meta-analysis

Includes: Supplementary data

Articles

Retraction: Long non-coding RNA ROR1-AS1 incudes tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway

Biosci Rep (2020) 40 (7): BSR-20191453_RET.

https://doi.org/10.1042/BSR-20191453_RET

Published: 17 July 2020

... Attribution License 4.0 (CC BY) . colorectal cancer Long noncoding RNA ROR1-AS1 Wnt/β-catenin signaling pathway This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. This article is being retracted from Bioscience Reports...

View articletitled, Retraction: Long non-coding RNA ROR1-AS1 incudes tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway

Articles

Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer

He Zhou, Yongfu Xiong, Guangjun Zhang, Zuoliang Liu, Lifa Li, Songlin Hou, Tong Zhou

Biosci Rep (2020) 40 (7): BSR20201503.

https://doi.org/10.1042/BSR20201503

Published: 09 July 2020

... of colorectal cancer (CRC). However, the roles of the MCM family in CRC remain largely unknown. Methods: Here, the expression, prognostic significance and functions of the MCM family in CRC were systematically analyzed through a series of online databases including CCLE, Oncomine, HPA, cBioPortal and cancerSEA...

View articletitled, Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer

Articles

Expression of Concern: Long non-coding RNA ROR1-AS1 incudes tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway

Biosci Rep (2020) 40 (7): BSR-20191453_EOC.

https://doi.org/10.1042/BSR-20191453_EOC

Published: 07 July 2020

... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Long noncoding RNA ROR1-AS1 colorectal cancer Wnt/β-catenin signaling...

View articletitled, Expression of Concern: Long non-coding RNA ROR1-AS1 incudes tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway

Articles

Retraction: Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with lynch syndrome like metastatic colorectal cancer

Biosci Rep (2020) 40 (7): BSR-20200225_RET.

https://doi.org/10.1042/BSR-20200225_RET

Published: 02 July 2020

... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Colorectal cancer In silico tools In vitro analysis Lynch syndrome MLH1...

View articletitled, Retraction: Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with lynch syndrome like metastatic colorectal cancer

Articles

Expression of Concern: Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with lynch syndrome like metastatic colorectal cancer

Biosci Rep (2020) 40 (6): BSR-20200225_EOC.

https://doi.org/10.1042/BSR-20200225_EOC

Published: 24 June 2020

... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Colorectal cancer Lynch syndrome WES MLH1 In silico tools In vitro...

View articletitled, Expression of Concern: Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with lynch syndrome like metastatic colorectal cancer

Articles

Colorectal cancer cells promote osteoclastogenesis and bone destruction through regulating EGF/ERK/CCL3 pathway

Gong Zi-chen, Qian Jin, Zhang Yi-na, Wang Wei, Kang Xia, Xu Wei, Wu Juan, Zheng Wei

Biosci Rep (2020) 40 (6): BSR20201175.

https://doi.org/10.1042/BSR20201175

Published: 24 June 2020

...Gong Zi-chen; Qian Jin; Zhang Yi-na; Wang Wei; Kang Xia; Xu Wei; Wu Juan; Zheng Wei Bone metastasis of colorectal cancer (CRC) cells leads to osteolysis. Aberrant activation of osteoclasts is responsible for bone resorption in tumor. In general, bone marrow-derived monocytes (BMMs) differentiate...

View articletitled, Colorectal cancer cells promote osteoclastogenesis and bone destruction through regulating EGF/ERK/CCL3 pathway

Articles

Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with Lynch syndrome like metastatic colorectal cancer

Komal Saleem, Tahir Zaib, Wei Ji, Chunhui Zhang, Qian Qin, Yusi Wang, Lidan Xu, Hanfei Yu, Siqi Zhu, Kexian Dong, Shuhan Si, Xueyuan Jia, Jie Wu, Songbin Fu, Wenjing Sun

Biosci Rep (2020) 40 (6): BSR20200225.

https://doi.org/10.1042/BSR20200225

Published: 03 June 2020

...Komal Saleem; Tahir Zaib; Wei Ji; Chunhui Zhang; Qian Qin; Yusi Wang; Lidan Xu; Hanfei Yu; Siqi Zhu; Kexian Dong; Shuhan Si; Xueyuan Jia; Jie Wu; Songbin Fu; Wenjing Sun Colorectal cancer (CRC) is the third most developing cancer worldwide and Lynch syndrome (LS) accounts for 3–4% of CRC. Genetic...

View articletitled, Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with Lynch syndrome like metastatic colorectal cancer

Includes: Supplementary data

Articles

WITHDRAWN: Long intergenic non-coding RNA LINC00662 contributes to malignant growth of colorectal cancer cells by upregulating c-myc via sponging microRNA-145

Zhifeng Yao, Danghui Xu, Zhanfeng Li, Jianxin Yao, Zhiyao Pan, Jinfei Chen

Biosci Rep (2020) BSR20200011.

https://doi.org/10.1042/BSR20200011

Published: 29 May 2020

... under a Creative Commons licence. colorectal cancer LINC00662 miR-145 c-myc competing endogenous RNAs WITHDRAWN ARTICLE WITHDRAWN: Long intergenic non-coding RNA LINC00662 contributes to malignant growth of colorectal cancer cells by upregulating c-myc via sponging microRNA-145 Zhifeng Yao...

View articletitled, WITHDRAWN: Long intergenic non-coding RNA LINC00662 contributes to malignant growth of colorectal cancer cells by upregulating c-myc via sponging microRNA-145

Articles

MIR600HG suppresses metastasis and enhances oxaliplatin chemosensitivity by targeting ALDH1A3 in colorectal cancer

Yi Yao, Nan Li

Biosci Rep (2020) 40 (4): BSR20200390.

https://doi.org/10.1042/BSR20200390

Published: 28 April 2020

...Yi Yao; Nan Li Background: Metastasis and chemoresistance indicate a poor prognosis in colorectal cancer (CRC) patients. However, the mechanisms that lead to the development of chemoresistance and metastasis in CRC remain unclear. Materials and methods: We combined clinical and experimental studies...

View articletitled, MIR600HG suppresses metastasis and enhances oxaliplatin chemosensitivity by targeting ALDH1A3 in colorectal cancer

Articles

Abnormal bowel movement frequency increases the risk of rectal cancer: evidence from cohort studies with one million people

Lin Shen, Chao Li, Na Li, Liangfang Shen, Zhanzhan Li

Biosci Rep (2020) 40 (4): BSR20200355.

https://doi.org/10.1042/BSR20200355

Published: 15 April 2020

...Lin Shen; Chao Li; Na Li; Liangfang Shen; Zhanzhan Li Previous studies from case–control studies failed to draw reliable conclusions regarding the relationship between bowel movement frequency and the risk of colorectal cancer. To further examine this relationship, we collect the data from cohort...

View articletitled, Abnormal bowel movement frequency increases the risk of rectal cancer: evidence from cohort studies with one million people

Includes: Supplementary data

Articles

Circulating lncRNA DANCR as a potential auxillary biomarker for the diagnosis and prognostic prediction of colorectal cancer

Xianjuan Shen, Yajing Xue, Hui Cong, Xudong Wang, Zhiwei Fan, Xiaopeng Cui, Shaoqing Ju

Biosci Rep (2020) 40 (3): BSR20191481.

https://doi.org/10.1042/BSR20191481

Published: 27 March 2020

...Xianjuan Shen; Yajing Xue; Hui Cong; Xudong Wang; Zhiwei Fan; Xiaopeng Cui; Shaoqing Ju Studies have shown that long non-coding RNAs (lncRNAs) play vital roles in the development of cancer, including colorectal cancer (CRC). Our purpose is to validate the diagnostic value of serum differentiation...

View articletitled, Circulating lncRNA DANCR as a potential auxillary biomarker for the diagnosis and prognostic prediction of colorectal cancer

Articles

APC gene 3′UTR SNPs and interactions with environmental factors are correlated with risk of colorectal cancer in Chinese Han population

Rongbiao Ying, Zhiping Wei, Yuxian Mei, Shasha Chen, Liming Zhu

Biosci Rep (2020) 40 (3): BSR20192429.

https://doi.org/10.1042/BSR20192429

Published: 20 March 2020

...Rongbiao Ying; Zhiping Wei; Yuxian Mei; Shasha Chen; Liming Zhu Objective: To study the correlation between adenomatous polyposis coli ( APC ) gene 3′ untranslated region (UTR) single nucleotide polymorphisms (SNPs) and their interactions with environmental factors and the risk of colorectal cancer...

View articletitled, APC gene 3′UTR SNPs and interactions with environmental factors are correlated with risk of colorectal cancer in Chinese Han population

Articles

Correction: Comprehensive analysis of long noncoding RNA and mRNA in five colorectal cancer tissues and five normal tissue

Biosci Rep (2020) 40 (3): BSR-20191139_COR.

https://doi.org/10.1042/BSR-20191139_COR

Published: 06 March 2020

... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . colorectal cancer mRNA profiling lncRNA profiling target gene functional analysis The authors of the original article ‘Comprehensive analysis of long noncoding RNA and mRNA in five colorectal...

View articletitled, Correction: Comprehensive analysis of long noncoding RNA and mRNA in five colorectal cancer tissues and five normal tissue

Articles

Comprehensive analysis of long noncoding RNA and mRNA in five colorectal cancer tissues and five normal tissues

Zhen-Xu Zhou, Xiao-Ming Chen, Yu-Qi Zhang, Liu Peng, Xiang-Yang Xue, Guo-Xin Li

Biosci Rep (2020) 40 (2): BSR20191139.

https://doi.org/10.1042/BSR20191139

Published: 14 February 2020

...Zhen-Xu Zhou; Xiao-Ming Chen; Yu-Qi Zhang; Liu Peng; Xiang-Yang Xue; Guo-Xin Li The present study investigated the role of abnormally expressed mRNA and long noncoding RNA (lncRNA) in the development of colorectal cancer (CRC). We used lncRNA sequencing to analyze the transcriptome (mRNA and lncRNA...

View articletitled, Comprehensive analysis of long noncoding RNA and mRNA in five colorectal cancer tissues and five normal tissues

Includes: Supplementary data

Articles

Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer

Guosen Wang, Weiwei Sheng, Jingtong Tang, Xin Li, Jianping Zhou, Ming Dong

Biosci Rep (2020) 40 (1): BSR20191488.

https://doi.org/10.1042/BSR20191488

Published: 17 January 2020

...Guosen Wang; Weiwei Sheng; Jingtong Tang; Xin Li; Jianping Zhou; Ming Dong Serine-arginine protein kinase 2 (SRPK2) is aberrantly expressed in human malignancies including colorectal cancer (CRC). However, little is known about the molecular mechanisms, and the role of SRPK2 in chemosensitivity...

View articletitled, Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer

Articles

Exopolysaccharides isolated from Rhizopus nigricans induced colon cancer cell apoptosis in vitro and in vivo via activating the AMPK pathway

Yan Lu, Xiujuan Zhang, Jiayue Wang, Kaoshan Chen

Biosci Rep (2020) 40 (1): BSR20192774.

https://doi.org/10.1042/BSR20192774

Published: 14 January 2020

...Yan Lu; Xiujuan Zhang; Jiayue Wang; Kaoshan Chen Colorectal cancer (CRC) is a leading cause of cancer-related human deaths. The exopolysaccharide (EPS1-1), isolated from Rhizopus nigricans , has been described as exhibiting anti-tumor and pro-apoptotic activity against CRC, although the underlying...

View articletitled, Exopolysaccharides isolated from Rhizopus nigricans induced colon cancer cell apoptosis in vitro and in vivo via activating the AMPK pathway

Includes: Supplementary data

Articles

Mismatch repair status between primary colorectal tumor and metastatic tumor, a retrospective consistent study

Zheng Wang, Xiaoli Tang, Xiaoqing Wu, Meiyuan Yang, Daorong Wang

Biosci Rep (2019) 39 (12): BSR20190730.

https://doi.org/10.1042/BSR20190730

Published: 13 December 2019

...Zheng Wang; Xiaoli Tang; Xiaoqing Wu; Meiyuan Yang; Daorong Wang Objectives Mismatch repair (MMR) and Microsatellite instability (MSI) are critical when considering immunotherapy and chemotherapeutic drugs an option for patients with colorectal cancer (CRC). We investigated the consistence of MMR...

View articletitled, Mismatch repair status between primary colorectal tumor and metastatic tumor, a retrospective consistent study

Articles

MiR-27b-3p promotes migration and invasion in colorectal cancer cells by targeting HOXA10

Xiangling Yang, Junxiong Chen, Yao Liao, Lanlan Huang, Chuangyu Wen, Mengmeng Lin, Weiqian Li, Yonglin Zhu, Xiaojian Wu, Aikichi Iwamoto, Zhongyang Wang, Huanliang Liu

Biosci Rep (2019) 39 (12): BSR20191087.

https://doi.org/10.1042/BSR20191087

Published: 06 December 2019

... oncogenes and tumor suppressor genes. One such example, miR-27b-3p, has reportedly been involved in tumor progression in many types of cancer. The aim of the present study was to delve into the role and the underlying mechanism of miR-27b-3p in colorectal cancer (CRC) cells. Methods: In the present study...

View articletitled, MiR-27b-3p promotes migration and invasion in colorectal cancer cells by targeting HOXA10

Articles

The association between IL-17 gene variants and risk of colorectal cancer in a Chinese population: A case–control study

Haiyang Feng, Rongbiao Ying, Tengjiao Chai, Hailang Chen, Haixing Ju

Biosci Rep (2019) 39 (11): BSR20190013.

https://doi.org/10.1042/BSR20190013

Published: 26 November 2019

...Haiyang Feng; Rongbiao Ying; Tengjiao Chai; Hailang Chen; Haixing Ju Interleukin (IL)-17 have been reported to be associated with the pathogenesis of colorectal cancer (CRC). Few studies investigated the association between IL-17 gene polymorphisms and risk of CRC with inconsistent findings. Thus...

View articletitled, The association between IL-17 gene variants and risk of colorectal cancer in a Chinese population: A case–control study

Articles

Long non-coding RNA ROR1-AS1 induces tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway

Wei Wang, Weihong Zheng, Lei Zhang, Ke Li

Biosci Rep (2019) 39 (11): BSR20191453.

https://doi.org/10.1042/BSR20191453

Published: 22 November 2019

...Wei Wang; Weihong Zheng; Lei Zhang; Ke Li Recent studies have discovered that long noncoding RNAs (lncRNAs) play an important role in malignant tumors. In this research, lncRNA ROR1-AS1 was selected to identify how it affects the development of colorectal cancer (CRC). ROR1-AS1 expression...

View articletitled, Long non-coding RNA ROR1-AS1 induces tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway

Articles

Silencing of lncRNA EZR-AS1 inhibits proliferation, invasion, and migration of colorectal cancer cells through blocking transforming growth factor β signaling

Zhenhua Liu, Ning Wang, Feiqing Wang, Shuaimin Zhang, Jie Ding

Biosci Rep (2019) 39 (11): BSR20191199.

https://doi.org/10.1042/BSR20191199

Published: 13 November 2019

...Zhenhua Liu; Ning Wang; Feiqing Wang; Shuaimin Zhang; Jie Ding Long non-coding RNA (lncRNA) plays a key regulatory role in the pathogenesis of colorectal cancer (CRC). In the present study, the specific regulatory role of lncRNA ezrin antisense RNA 1 (EZR-AS1) on CRC was investigated...

View articletitled, Silencing of lncRNA EZR-AS1 inhibits proliferation, invasion, and migration of colorectal cancer cells through blocking transforming growth factor β signaling

Articles

Development and validation of nomogram combining serum biomarker for predicting survival in patients with resected rectal cancer

Shaonan Fan, Ting Li, Ping Zhou, Qiliang Peng, Yaqun Zhu

Biosci Rep (2019) 39 (11): BSR20192636.

https://doi.org/10.1042/BSR20192636

Published: 13 November 2019

... 26 09 2019 21 10 2019 22 10 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . CEA colorectal cancer Nomogram...

View articletitled, Development and validation of nomogram combining serum biomarker for predicting survival in patients with resected rectal cancer

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