... of DnaA on the membrane and pointing to the possibility that membrane protein density serves as an on-off switch in vivo . We conclude that the DnaA conformation attained at low surface density drives its N-terminal-mediated oligomerization, which is presumably a pre-requisite for facilitated nt exchange...

...Sandro Sonnino; Paola Brocca; Domenico Acquotti; Anna Bernardi; Laura Raimondi; Makoto Kiso; Hideharu Ishida; Su-Chen Li; Yu-Teh Li The conformational properties of GM2, GalNacβ-4(Neu5Acα-3) Galβ-4Glcβ-1Cer have been compared to those of 6′-GM2, in which the linkage between the GalNAc and Gal...

.... Presumably these enzymes would also respond to endogenous transmembrane electric fields of similar intensity and waveform. A mechanism is proposed in which energy coupling is achieved via Coulombic interaction of an electric field and the conformational equilibria of an ATPase. Analysis indicates that only...

..., diffusional control is prevented by the excess of collisional encounters between fast-diffusing ubiquinone and the respiratory complexes. Another aspect of dynamics of membrane proteins is their conformational flexibility. Lipids may induce the optimal conformation for catalytic activity. Breaks in Arrhenius...

...Jaap J. Beintema X-ray structures of the conformation of carbohydrate moieties and connected regions of glycoproteins are summarized. Evidence is presented that there is some preference for carbohydrate attachment at β-bends. Evolution may have favored glycosylation to occur at bends to ensure free...