...David Perrais Dynamin is one of the major proteins involved in endocytosis. First identified 50 years ago in a genetic screen in Drosophila melanogaster , it has become a central player in many forms of endocytosis, such as clathrin-mediated endocytosis or synaptic vesicle endocytosis, as well...

... 4b activity [ 17 ]. Thus, MAGUK proteins appear to regulate both the subcellular localization and function of the receptor. extracellular signal-regulated kinases estrogens endocytosis G-protein-coupled receptors glycosylation trafficking The topology of G protein-coupled receptors...

... endocytosis integrins rab gtpases Extracellular signals and integrin engagement trigger internalisation and recycling of membrane-bound receptors and integrins through various pathways, depending on the context and cell type. Cells vary their trafficking of adhesion and signalling receptors through...

...Ming Zhang; Li Chen; Shicong Wang; Tuanlao Wang The endocytosis pathway controls multiple cellular and physiological events. The lysosome is the destination of newly synthesized lysosomal hydrolytic enzymes. Internalized molecules or particles are delivered to the lysosome for degradation through...

... in these cells; and (iii) evidence suggesting regulation of GLUT4 endocytosis in muscle cells by signals associated with muscle contraction. Several mechanisms of internalization from the plasma membrane exist in mammalian cells that display distinct commonalities and differences (reviewed in [ 11 – 13...

...–OxLDL into endosomal structures, whereas empty-vector-transfected cells failed to do so, indicating that, unlike the C-terminal cytoplasmic domain, the N-terminal cytoplasmic domain is not essential for the endocytosis of OxLDL. In conclusion, the uptake of OxLDL by CD36 is not reliant on the presence...

... efficient in vivo gene delivery protocols. © 2006 Springer Science+Business Media, LLC 2006 Cationic lipid Cell uptake Endocytosis Gene therapy Gene delivery Nuclear import Plasmid DNA Stability Transfection Abstract Cationic lipids are conceptually and methodologically simple tools...

... Publishing Corporation 2001 Dendritic cells membrane lectins endocytosis glyco-clusters invertase glycosynthons Bioscience Reports, Vol. 21, No. 6, December 2001 ( 2002) Uptake of Dimannoside Clusters and Oligomannosides by Human Dendritic Cells Laurent Be´douet,1,2 Marie-The´re`se Bousser,1...

... the endo/exocytotic cycle. Uptake of dye wasindependent of temperature, Na + /K+ gradients, pH or metabolism. Wesuggest that passive accumulation of FM1–43 can occur in cancer cells andshould not, automatically, be interpreted as evidence of endocytosis. © 2000 Plenum Publishing Corporation 2000...

... endosomes and lysosomes of these cells are long living organelles with a high content of internal membranes. Our studies show that during endocytosis the biotin-GM1 was transported to these intraendosomal and intralysosomal membranes. These observations support the hypothesis that glycosphingolipids (GSL...

...Robert J. Lee; Susan Wang; Mary Jo Turk; Philip S. Low Targeted liposomal drug formulations may enter cells by receptor-mediated endocytosis and then traffick by membrane flow into acidic intracellular compartments. In order to understand the impact of these intracellular pH changes on liposomal...

... to determine minimal time requirements for exocytosis-coupled endocytosis to occur, we have analyzed by electron microscopy uptake of horserdish peroxidase (HRP) as a fluid phase marker at the onset of depolarization. We have applied rapid mixing and sampling (quenched flow) to assess events in subsecond time...

... in cellular functions that control endocytosis and/or exocytosis. 8 6 1987 © 1987 Plenum Publishing Corporation 1987 Ras protein membrane turnover exocytosis endocytosis Bioscience Reports, Vol. 7, No. 5, 1987 Regulation of Membrane Turnover by Ras Proteins Dafna Bar-Sagi, Anne...

... controls the fusion between different vesicles on the pathway. endocytosis cell-free vesicle fusion fusion 9 4 1987 © 1987 Plenum Publishing Corporation 1987 Bioscience Reports, Vol. 7, No. 4, 1987 A Cell-Free Analysis of the Pathway John Davey Received April 9, 1987 KEY WORDS...