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Keywords: endosomes
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Articles

Mechanisms regulating the sorting of soluble lysosomal proteins

Open Access
İçten Meraş, Juliette Maes, Stephane Lefrancois
Journal: Bioscience Reports
Biosci Rep (2022) 42 (5): BSR20211856.
https://doi.org/10.1042/BSR20211856
Published: 13 May 2022
... disease. endoplasmic reticulum endosomes intracellular transport Lysosomes neurodegeneration neuronal ceroid lipofuscinosis First discovered by Christian de Duve, lysosomes perform several key cellular functions, and their dysfunction has been implicated in several human pathologies...
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Articles

Subcellular trafficking of guanylyl cyclase/natriuretic peptide receptor-A with concurrent generation of intracellular cGMP

Open Access
Indra Mani, Renu Garg, Satyabha Tripathi, Kailash N. Pandey
Journal: Bioscience Reports
Biosci Rep (2015) 35 (5): e00260.
https://doi.org/10.1042/BSR20150136
Published: 30 October 2015
... of enhanced GFP (eGFP)-tagged NPRA (eGFP–NPRA) in human embryonic kidney-293 (HEK-293) cells, using immunofluorescence (IF) and co-immunoprecipitation (co-IP) of eGFP–NPRA. Treatment of cells with ANP initiated rapid internalization and co-localization of the receptor with early endosome antigen-1 (EEA-1...
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Includes: Supplementary data