... cardiac function and protect myocardial cells. The study aims to investigate the effects of AS-IV on ventricular remodeling and explore its role in regulating energy metabolism using a rat CHF model. Sprague–Dawley rats were divided into five groups ( n =20 per group): CHF + benazepril hydrochloride...

... in a process called mitochondrial permeability transition (mPT) that also leads to cell death [ 63 ]. calcium homoeostasis energy metabolism fatty acids fatty acid oxidation disorders mitochondrial dysfunction redox homoeostasis Fatty acid oxidation defects (FAOD) are inherited metabolic...

... energy metabolism endoplasmic reticulum (ER) stress Cadmium is an environmental pollutant and a highly toxic metal ion, accumulated largely in the liver and kidney [ 1 , 2 ]. Chronic exposure of humans to a cadmium-contaminated environment or food chain may be implicated in some human disorders...

...Luís Rato; Marco G. Alves; Sílvia Socorro; Rui A. Carvalho; José E. Cavaco; Pedro F. Oliveira Sertoli cells actively metabolize glucose that is converted into lactate, which is used by developing germ cells for their energy metabolism. Androgens and oestrogens have general metabolic roles...

... for real-time PCR analysis of the gene expression of enzymes and regulatory factors of liver energy metabolism. Most hepatic proteins showed similar gene expressions in OE and controls, but the differences widened between OE and PF rats, showing that OE effects could not be merely attributed to a lower...

...-time PCR) expression of lipid and energy metabolism genes for enzymes and regulatory proteins were measured. BAT mass and lipid were decreased in OE and PF, with the latter showing a marked reduction in tissue mRNA. Maintenance of perilipin gene expression in PF and OE rats despite the loss of lipid...

... the mitochondrial energy metabolism in response of cells to stress situations. Indeed, the expression and function of these proteins in non-thermogenic tissues suggest that their primary functions are not related to heat production. © 2005 Springer Science+Business Media, Inc. 2005 PUMP AOx mitochondria...

... Publishing Corporation 2002 ATP concentration energy charge energy metabolism adenylate pool adenylate metabolism pools of cofactors Bioscience Reports, Vol. 22, Nos. 5 and 6, October and December 2002 ( 2002) What Determines the Intracellular ATP Concentration Fazoil I. Ataullakhanov1,2,3...

...Fernando Goglia; Elena Silvestri; Antonia Lanni Because of their central role in the regulation of energy-transduction, mitochondria, the major site of oxidative processes within the cell, are considered a likely subcellular target for the action that thyroid hormones exert on energy metabolism...

... shown to modulate the activity of various immune effector cells directly via membrane adrenergic receptors. Here, we investigated immediate effects of norepinephrine on energy metabolism of immune cells. Norepinephrine inhibits oxygen consumption of human peripheral blood mononuclear cells...

... glucocorticoids at high doses they are assumed to produce their effects at least in part by direct membrane stabilizing effects. In order to prove this hypothesis, we have investigated in this study the effects of these drugs on the energy metabolism of activated human peripheral blood mononuclear cells (PBMC...

...Dirk Schmid; Gerd-Rüdiger Burmester; Robert Tripmacher; Antje Kuhnke; Frank Buttgereit The first quantitative findings on the energy metabolism of human immunecells are presented. In quiescent peripheral blood mononuclear cells(PBMC) protein biosynthesis and Na + ,K + -ATPase activity eachaccounted...

...Frank Buttgereit; Marianne Müller; Karsten Wolbart; Bernhard Thiele; Falk Hiepe Using Ehrlich ascites tumour cells, the short-term effects of the therapeutic glucocorticoid Methylprednisolone (MP) on the cellular energy metabolism were studied. ATP-consuming processes involved in the rapid MP...

...Frank Buttgereit; Martin D. Brand; Marianne Müller The short-term effects of high concentrations of Methylprednisolone (MP) on the energy metabolism of quiescent and Concanavalin A-stimulated rat thymocytes were investigated in vitro. Concanavalin A (ConA) stimulated the respiration rate...

...F. Buttgereit; M. D. Brand; M. Müller The influence of ConA on the energy metabolism of quiescent rat thymocytes was investigated by measuring the effects of inhibitors of protein synthesis, proteolysis, RNA/DNA synthesis, Na + K + -ATPase, Ca 2+ -ATPase and mitochondrial ATP synthesis...

...F. Buttgereit; M. D. Brand; M. Müller The influence of ConA on the energy metabolism of quiescent rat thymocytes was investigated by measuring the effects of inhibitors of protein synthesis, proteolysis, RNA/DNA synthesis, Na + K + -ATPase, Ca 2+ -ATPase and mitochondrial ATP synthesis...