1-15 of 15
Keywords: gene therapy
Close
Sort by
Articles
Biosci Rep (2021) 41 (1): BSR20201026.
Published: 06 January 2021
... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . chitosan gene therapy HEK293T cells IGFBP nuclear localization signals Gene therapy entails the transfer of therapeutic...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20181258.
Published: 10 June 2019
... 2018 09 04 2019 30 04 2019 28 05 2019 Correspondence: Jianjun Jin ( [email protected] ) FGFR1 gastric cancer gene therapy miR-198 miRNA Gastric cancer (GC) is a prevalent cancer and a leading cause of cancer-related deaths around the globe, particularly...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (1): BSR20180773.
Published: 30 January 2019
... 2018 19 12 2018 13 01 2019 14 01 2019 aberrant expression status chromosome remodeling gene therapy inhibitor of growth 4 mechanisms non-neoplastic diseases Tumor suppressor genes (TSGs) can oppose oncogene function and restrain cancer development, with inactivation...
Articles
Biosci Rep (2018) 38 (5): BSR20180516.
Published: 23 October 2018
... RNA microRNA oncogenesis gene therapy Autophagy is a process of sustaining metabolism and homeostasis by capturing and degrading intracellular components such as proteins and organelles. Autophagy plays an important role in protein and organelle quality control, knowing that a low level...
Articles
Biosci Rep (2018) 38 (5): BSR20181109.
Published: 07 September 2018
... and its induction was achieved with low Dox concentrations. Remarkably, the intracellular regulatory expression of 2LTRZFP significantly inhibited HIV-1 integration and replication in HIV-inoculated SupT1 cells. This approach could provide a potential tool for gene therapy applications, which efficiently...
Articles
Biosci Rep (2017) 37 (6): BSR20160616.
Published: 29 November 2017
... ]. © 2017 The Author(s). 2017 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cytoskeleton cell nucleus gene therapy intracellular transport microtubule...
Articles
Biosci Rep (2016) 36 (6): e00427.
Published: 09 December 2016
... and assess whether targeting this pathway has potential for reducing neointima formation. We utilized a gene therapy approach selectively targeting cells in which the β-catenin/TCF pathway is activated by using a recombinant adenovirus Ad-TOPTK, which carries a herpes simplex virus thymidine kinase (HSV-TK...
Articles
Articles
Biosci Rep (2014) 34 (5): e00140.
Published: 02 October 2014
... is a promising method that allows the targeting of gene therapy for heart failure. Furthermore, we found that the treated animals (liposomal magnetofection with shIGF1R) showed reduced septal and posterior wall thickness, reduced HW:BWs (heart weight-to-body weights) compared with controls. Moreover, we also...
Articles
Biosci Rep (2007) 27 (1-3): 151–163.
Published: 13 June 2007
.... © 2007 The Biochemical Society 2007 MNGIE Thymidine phosphorylase Thymidine Deoxyuridine Stem cells Gene therapy ORI GI N A L P A PE R Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): Biochemical Features and Therapeutic Approaches M. C. Lara Æ M. L. Valentino Æ J. Torres...
Articles
Biosci Rep (2006) 26 (4): 301–324.
Published: 26 October 2006
... efficient in vivo gene delivery protocols. © 2006 Springer Science+Business Media, LLC 2006 Cationic lipid Cell uptake Endocytosis Gene therapy Gene delivery Nuclear import Plasmid DNA Stability Transfection Abstract Cationic lipids are conceptually and methodologically simple tools...
Articles
Articles
Biosci Rep (2002) 22 (2): 283–295.
Published: 01 April 2002
... Corporation 2002 Liposomes non-viral delivery systemic delivery gene therapy optimization Bioscience Reports, Vol. 22, No. 2, April 2002 ( 2002) MINI REVIEW Cationic Liposome-mediated Gene Delivery In vivo Nancy Smyth Templeton Receiûed Noûember 1, 2001 Several improvements have been made...
Articles
Biosci Rep (2002) 22 (2): 151–173.
Published: 01 April 2002
... attention to polyunsaturated lipids, membrane proteins and ion channels, surfactant additives in membranes, and lipid–DNA gene transfer complexes. © 2002 Plenum Publishing Corporation 2002 Biomembranes membrane proteins lipid–DNA complexes lipid–protein interactions gene therapy polyunsaturated...
Articles
Biosci Rep (2000) 20 (5): 419–432.
Published: 01 October 2000
... showed significantly less cytotoxicity compared to the commonly used cationic lipsomes or PEI mediated transfection and several cell lines were transfected with high efficiency. LPDII vectors avoid the use of toxic cationic lipids and may have potential application in gene therapy. © 2000 Plenum...