... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis glucose intervertebral disc degeneration nucleus pulposus...

... (LNS-PLW) on appetite score, energy intake, insulin and glucose levels in preeclamptic women. Design and participiants: Sixty under-weight preeclamptic primigravida were divided into two groups randomly and provided LNS-PLW/placebo in the fasted state. Blood samples were collected at fasting state...

... study was to investigate the insulinotropic and antidiabetic properties of ethanol extract of Acacia arabica (EEAA) bark through in vitro and in vivo studies in high fat-fed (HFF) rats. EEAA at 40–5000 µg/ml significantly increased ( P <0.05–0.001) insulin secretion with 5.6 and 16.7 mM glucose...

...Xinlu Pan; Mysore K. Phanish; Deborah L. Baines; Mark E.C. Dockrell Background: In the kidney glucose is freely filtered by the glomerulus and, mainly, reabsorbed by sodium glucose cotransporter 2 (SGLT2) expressed in the early proximal tubule. Human proximal tubule epithelial cells (PTECs) undergo...

..., namely, PubMed, Web of Science, Embase and Cochrane Library, to find eligible studies. Searches for all published articles relevant to glucose control and COVID-19 were performed. The following search items were used: ‘glucose control’, ‘glucose’, ‘glycemic’, ‘HbA1c’, ‘coronavirus’, ‘SARS’, ‘2019 novel...

.... Our study investigated the effects of glucose-induced miR-218 expression on human RPE cells (ARPE-19), as well as its targeted regulatory effect. Methods: The levels of miR-218 and runt-related transcription factor 2 (RUNX2) expression were investigated by RT-qPCR or Western blot assays. Cell...

... the degenerative disc. Resveratrol is a newly identified phytoalexin that has protective effects on cartilaginous tissue. Objective: To investigate the whether resveratrol can protect against high glucose-induced NP cell apoptosis and senescence, and the potential mechanism in this process. Methods: Rat NP cells...

...María M. Adeva-Andany; Noemi Pérez-Felpete; Carlos Fernández-Fernández; Cristóbal Donapetry-García; Cristina Pazos-García Information about normal hepatic glucose metabolism may help to understand pathogenic mechanisms underlying obesity and diabetes mellitus. In addition, liver glucose metabolism...

.... Here we show the carbohydrate-binding domain is crucial for its stability and ability to bind to several glycogen-associated proteins. CBM20 endoplasmic reticulum glucose glycogen STBD1 ubiquitination STBD1 (starch-binding domain-containing protein 1; also known as Genethonin-1...

...Abdel Hebbachi; David Saggerson Palmitate increased AMPK (5′-AMP-activated protein kinase) activity, glucose utilization and 2-DOG (2-deoxyglucose) transport in rat adipocytes. All three effects were blocked by the AMPK inhibitor Compound C, leading to the conclusion that in response to an increase...

...Ikhlass Tabidi; David Saggerson Incubation of adult rat cardiac myocytes with increasing glucose concentrations decreased phosphorylation (αThr 172 ) and activity of AMPK (AMP-activated protein kinase). The effect could be demonstrated without measurable changes in adenine nucleotide contents...

...Albert Salehi; Fariborz Parandeh; Ingmar Lundquist The nature of the action of the nitric oxide synthase (NOS) inhibitor N G -nitro-L-arginine methyl ester (L-NAME) on hormone release from isolated islets was investigated. We found that glucose-induced insulin release was potentiated by L-NAME...

...Stephen A. Baldwin; L. Felipe Barros; Mark Griffiths The uptake of glucose into mammalian cells, catalysed by members of the GLUT family of glucose transporters, is regulated by a variety of hormones, growth factors and other agents. In adipocytes, skeletal muscle and heart the principal regulator...

...Neus Carbó; Francisco J. López-Soriano; Josep M. Argilés Hepatocytes isolated from obese Zucker rats showed a significantly higher rate of both [U- 14 C]glucose and [U- 14 C]lactate incorporation into [ 14 C]lipid than those from their lean counterparts. This was associated with a marked increase...

...F. A. A. Al-Ahmed; E. S. M. El-Denshary; M. Zaki; H. A. El-Sawaf; A. R. Abu-Jayyab This study was undertaken to investigate the effect of diazepam in the presence and absence of glibenclamide, metformin or their combination on serum levels of glucose, insulin and chromium in rats. Results indicated...

...S. Vilaró; O. Viñas; E. Herrera; X. Remesar Chronic and acute ethanol treatments increased the 3-hydroxybutyrate uptake by lactating rat mammary gland as a consequence of its high afferent concentration, without changing its relative extraction. The uptake of glucose was inhibited in the ethanol...

...Nils Wesslén; Peter Bergsten; Bo Hellman The sodium contents of β-cell-rich pancreatic islets from ob/ob -mice were measured with an integrating flame photometer. After washing to an apparent steady state with different types of ice-cold media, islets incubated in the absence of glucose contained...