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Keywords: heparan sulphate
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Articles
Angelika Falsone, Veronica Wabitsch, Elena Geretti, Heide Potzinger, Tanja Gerlza, James Robinson, Tiziana Adage, Mauro M. Teixeira, Andreas J. Kungl
Journal:
Bioscience Reports
Biosci Rep (2013) 33 (5): e00068.
Published: 17 September 2013
...-coupled receptors), CXCR1 (CXC chemokine receptor 1) and CXCR2, for which additional binding to endothelial HS-GAGs (heparan sulphate-glycosaminoglycans) is required. We present here a novel approach for blocking the CXCL8-related inflammatory cascade by generating dominant-negative CXCL8 mutants...
