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Articles

Antifungal curcumin induces reactive oxygen species and triggers an early apoptosis but prevents hyphae development by targeting the global repressor TUP1 in Candida albicans

Monika Sharma, Raman Manoharlal, Nidhi Puri, Rajendra Prasad
Journal: Bioscience Reports
Biosci Rep (2010) 30 (6): 391–404.
DOI: https://doi.org/10.1042/BSR20090151
Published: 24 September 2010
... could be reversed by the addition of natural and synthetic antioxidants. Notably, independent of ROS status, polyphenol CUR prevented hyphae development in both liquid and solid hypha-inducing media by targeting the global suppressor TUP1 (thymidine uptake 1). Taken together, our results provide...
View article titled, Antifungal curcumin induces reactive oxygen species and triggers an early apoptosis but prevents <span class="search-highlight">hyphae</span> development by targeting the global repressor TUP1 in Candida albicans
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Includes: Supplementary data