... become a significant concern for public health. Obesity is highly prevalent worldwide and is considered a risk factor for impairing the adaptive immune system. Although diabetes, hypertension, cardiovascular disease (CVD), and renal failure are considered the risk factors for COVID-19, obesity is not yet...

... License 4.0 (CC BY) . Ca2+-influx immune regulation Immunity T-cells TRPA1 Transient receptor potential cation channel subfamily A member 1 (TRPA1) is the only member of the mammalian ‘ankyrin’ type subfamily of TRP channels [ 1 ]. TRPA1 is a calcium ion (Ca 2+ )-permeable non-selective...

... and analyzed the protein bands of interest. To make comparisons, we used β-actin expression as a control. immunity intestinal epithelial barrier oxidative stress Oxymatrine RhoA/ROCK pathway ulcerative colitis A standard IHC procedure was performed [ 28 ], in which 4% paraformaldehyde...

... it a serious global public health challenge. Influenza virus’s surface glycoproteins, hemagglutinin and neuraminidase, are all modified by the host cell’s N-linked glycosylation pathways. Host innate immune responses are the first line of defense against infection, and glycosylation of these major antigens...

...Peter C. Doherty The discovery of the molecular nature of T cell-mediated immunity is reviewed in a historical context. Current approaches to understanding virus-induced inflammatory processes are described. © 1997 Plenum Publishing Corporation 1997 Cell mediated immunity...

.... Bioscience Reports, Vol. 17, No. 2, 1997 NOBEL LECTURE DECEMBER 8, 1996 Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens Rolf M. Zinkernagel The experiments leading to the discovery of MHC-restricted T-cell killing of virus-infected cells are described. The implications...

...M. Wachsman; L. Aurelian; J. C. R. Hunter; M. E. Perkus; E. Paoletti We studied the effect of the temporal regulation of herpes simplex virus (HSV) type 1 glycoprotein D (gD-1) expression in Ia + epidermal cells (EC) and macrophages on virus specific immunity and protection from HSV-2 challenge. gD...