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Keywords: inflammation
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Biosci Rep (2024) 44 (4): BSR20231904.
Published: 16 April 2024
... burden. This perpetual inflammation by cytokines provokes numerous pernicious effects, including tissue damage, oxidative stress, fibrosis, and necrosis [ 61–64 ]. Our study shows that these inflammatory cytokines perturb RPE metabolism, potentially destabilizing the retina’s intricate metabolic balance...
Includes: Supplementary data
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Biosci Rep (2024) BSR20231347.
Published: 23 February 2024
... and it positively regulates psoriatic keratinocyte proliferation. Our data also showed that GPR15LG could regulate the activity of NF-κB pathway which is associated with psoriatic inflammation. In current study, we demonstrated that Gpr15lg (ortholog of GPR15LG ) knockdown attenuated the severity of imiquimod (IMQ...
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Biosci Rep (2023) 43 (10): BSR20230114.
Published: 31 October 2023
...-methyltetradecanoic acid, 12-MTA) on selected genes related to fatty acid synthesis and inflammation: FASN , SREBP1 , CRP , and IL-6 in the HepG2 cell line. We observed lowered expression of FASN , SREBP1 , CRP , and IL-6 in cells treated with 14-MPA in comparison with control cells. In contrast, supplementation...
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Biosci Rep (2023) 43 (3): BSR20220200.
Published: 09 March 2023
... AT inflammation is prevalent during obesity. The adipose tissue macrophages (ATM) with astounding heterogeneity and complex regulation play a decisive role in mediating obesity-induced insulin resistance. Adipose-derived macrophages were broadly classified as proinflammatory M1 and anti-inflammatory M2 subtypes...
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Biosci Rep (2023) 43 (1): BSR20220284.
Published: 06 January 2023
... dystrophies that intrinsically compromise MuSC function and/or disturb their microenvironment leading to impaired muscle regeneration that contributes to disease progression. Alternatively, many acquired myopathies caused by comorbidities (e.g., cardiopulmonary or kidney diseases), chronic inflammation...
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Biosci Rep (2022) 42 (9): BSR20211986.
Published: 05 September 2022
... Antigen presenting cell Graft-versus-host disease Inflammation Lymphocyte Xenogeneic graft-versus-host disease Graft-versus-host disease (GVHD) is an inflammatory disorder that can occur following allogeneic haematopoietic stem cell transplantation (HSCT) [ 1 , 2 ]. Allogeneic HSCT...
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Biosci Rep (2022) 42 (7): BSR20220251.
Published: 15 July 2022
...Victory Ibigo Poloamina; Wondwossen Abate; Gyorgy Fejer; Simon K. Jackson Inflammation is central to several diseases. TLR4 mediates inflammation by recognising and binding to bacterial lipopolysaccharides and interacting with other proteins in the TLR4 signalling pathway. Although...
Includes: Supplementary data
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Biosci Rep (2021) 41 (10): BSR20203573.
Published: 12 October 2021
... that thrombospondin-1 (TSP-1) is highly expressed in response to inflammation. In this work, we isolated and identified human thymic mesenchymal stromal cells (tMSCs) and detected the expression of TSP-1. We found that tMSCs expressed TSP-1 and Poly (I:C) or LPS treatment promoted the expression of TSP-1. Further, we...
Includes: Supplementary data
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Biosci Rep (2021) 41 (7): BSR-2019-2668_COR.
Published: 02 July 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adiponectin human periodontal ligament cells inflammation...
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Biosci Rep (2021) 41 (6): BSR20203850.
Published: 11 June 2021
... to preserve intestinal homoeostasis, promote protective immune responses, and limit excessive inflammation. The importance of the microbiome is further highlighted during dysbiosis where a loss of this finely balanced microbial population can lead to mucosal barrier dysfunction, aberrant immune responses...
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Biosci Rep (2021) 41 (4): BSR-20192639_RET.
Published: 19 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . acute lung injury apoptosis inflammation PPARγ PTEN/β-catenin pathway...
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Biosci Rep (2021) 41 (3): BSR20204247.
Published: 24 March 2021
... asthma patients. Previous studies have suggested that ACG has favorable therapeutic effect in clinic [ 17 ], and significantly suppresses ovalbumin (OVA)-induced asthma in pre-clinical studies. The anti-asthma mechanism of ACG is associated with reduced airway inflammation and tracheal smooth muscle...
Includes: Supplementary data
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Biosci Rep (2021) 41 (3): BSR20192668.
Published: 02 March 2021
...Huan-huan Wu; Yuan Guo; Yin-fei Pu; Zhi-hui Tang Periodontal diseases are infections of the structures that surround and support the teeth; they are characterized by local inflammation and alveolar bone loss. Most treatments focus on only one aspect, inhibiting inflammation, or promoting...
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Biosci Rep (2020) 40 (10): BSR20201098.
Published: 23 October 2020
... against this condition. The present study aims to investigate the protective effect of Zanthoxylum nitidum (ZN) on BMP-2-related hyperpermeability and inflammation on the human umbilical vein endothelial cells (HUVECs). The results revealed that, in a concentration-dependent manner, BMP-2 enhanced...
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Biosci Rep (2020) 40 (9): BSR20192910.
Published: 21 September 2020
... of inflammation and endothelial dysfunction markers among Egyptian females with different obesity classes. Methods: Out of 130 females, 70 were categorized into three obesity groups: Class I, body mass index (BMI) 30–34.9 kg/m 2 ; Class II, BMI 35–39.9 kg/m 2 and Class III BMI ≥ 40 kg/m 2 , besides 60 control...
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Biosci Rep (2020) 40 (8): BSR20201169.
Published: 20 August 2020
... published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . CXCL8 ERK Inflammation liver cancer malignant progression Liver cancer, the predominant primary malignancy, ranks as the fifth most...
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Biosci Rep (2020) 40 (7): BSR-20193431_COR.
Published: 30 July 2020
... The original article “Naringin protects endothelial cells from apoptosis and inflammation by regulating the Hippo-YAP Pathway” ( Biosci Rep (2019) 40 (3), DOI: 10.1042/BSR20193431) contained an image error and an incorrect description of the data presented. The authors state that they had...
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Biosci Rep (2020) 40 (7): BSR-20192536_COR.
Published: 03 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biochemical haemolysis histology inflammation safety Surveillance...
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Biosci Rep (2020) BSR20192842.
Published: 18 June 2020
... Commons licence. Curcumin Imiquimod Psoriasis IL-6 STAT3 Inflammation WITHDRAWN ARTICLE WITHDRAWN: Curcumin against imiquimod-induced psoriasis of mice through IL-6/STAT3 signaling pathway Yibin Zeng; Hongying Zhao; Tong Zhang; Chao Zhang; Yanni He; Lingbo Du; Fuguo Zuo; Wuqing Wang Biosci...
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Biosci Rep (2020) 40 (6): BSR20194486.
Published: 17 June 2020
... transfected for 48 h, 10 µl of CCK-8 was added to each well and incubated at 37°C for 1 h. Cell viability was measured at 450 nm using a microplate reader. inflammation lncRNA DILC neuropathic pain SOCS3 the JAK2/STAT3 pathway Neuropathic pain occurs from lesions or diseases affecting...
Includes: Supplementary data
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Biosci Rep (2020) 40 (6): BSR20192536.
Published: 05 June 2020
.... The lungs showed alveolar with evidence of inflammation and foci of epithelial sloughing. Alveolar spaces were also obscured by debris and inflammatory cells. HPA and HPC produced scattered intensely congested heart vessels while HPB(10) produced haemorrhage and amorphous exudates within the heart. All HMPs...
Includes: Supplementary data
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