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Keywords: inhibitory activity
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Ethers and esters derived from apocynin avoid the interaction between p47 phox and p22 phox subunits of NADPH oxidase: evaluation in vitro and in silico

Open Access
Martha Edith Macías-Pérez, Federico Martínez-Ramos, Itzia Irene Padilla-Martínez, José Correa-Basurto, Lowell Kispert, Jessica Elena Mendieta-Wejebe, Martha Cecilia Rosales-Hernández
Journal: Bioscience Reports
Biosci Rep (2013) 33 (4): e00055.
https://doi.org/10.1042/BSR20130029
Published: 02 August 2013
... derivatives were determined. A docking study was used to identify the interactions between the NOX2′s p47 phox subunit and apocynin or its derivatives. The results showed that all of the compounds exhibit inhibitory activity on NOX, being 4 the best derivative. However, neither apocynin nor its derivatives...
View articletitled, Ethers and esters derived from apocynin avoid the interaction between p47 phox and p22 phox subunits of NADPH oxidase: evaluation in vitro and in silico
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