... disease (CAD) and ischemic stroke. A total of 15 eligible studies were extracted from electronic databases. Odds ratios (ORs) were presented, with 95% confidence intervals (CIs), to assess the associations. Meta-analysis was conducted using MetaGenyo, STATA, and Comprehensive Meta-Analysis. Meta-analysis...

...) by screening for miRNA expression in ischemic stroke and normal samples. Methods: Differentially expressed miRNA (DEM) analysis was conducted using limma R Bioconductor package. Target genes of DEMs were identified from TargetScanHuman and miRTarBase databases. Functional enrichment analysis of the target...

...Jiahui Li; Zhijie Liu; Liling Wang; Haiyan Xu; Yulin Wang Background: Birth hypoxia causes neonatal mortality and morbidity. Hypoxia/ischemia can facilitate brain damage, causing various kinds of diseases, such as ischemic stroke. It is necessary to understand the potential underlying mechanisms...

...Jing Tian; Yongjie Bai; Aimin You; Ruile Shen; Junqiang Yan; Wenjing Deng; Lijun Wen; Meng Li; Junfang Teng Objective: To study the relationship between Interleukin-17 receptor C (IL-17RC) gene polymorphism and ischemic stroke (IS). Methods : Three hundred cases of IS patients and 300 cases...

... of TMAO in Chinese patients with ischemic stroke. Method : In the present study, 255 consecutive patients with first-ever acute ischemic stroke and 255 age and gender-matched healthy volunteers were included for testing serum TMAO. Stroke severity was determined by the NIH Stroke Scale (NIHSS). The stroke...

... ischemic stroke. Seventy-seven IS patients and forty-two healthy controls matched for age and sex were enrolled in the present study. Blood samples were drawn from IS patients within the 24 h. The correlation analysis was performed by Spearman. The ability to distinguish patients from healthy controls...

...Yan-yan Zhu; Jian-long Zhang; Li Liu; Yingbo Han; Xiaomin Ge; Shuai Zhao The aim was to investigate the relationship between retinol-binding protein 4 (RBP4) levels and short-term functional outcome, and to determine its possible role in acute ischemic stroke (AIS). In a prospective observational...

...Siou Li; Changhao Yin; Weina Zhao; Haifu Zhu; Dan Xu; Qing Xu; Yang Jiao; Xue Wang; Hong Qiao Whether insulin resistance (IR) predicts worse functional outcome in ischemic stroke is still a matter of debate. The aim of the present study is to determine the association between IR and risk of poor...

... amongst ischemic stroke patients at different time points [ 8–10 ]. © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . 25...

...) and ischemic stroke (IS). The present study aimed to determine the TIMD4-HAVCR1 variants, their haplotypes and gene–environment interactions on serum lipid levels, the risk of CHD and IS, and the lipid-lowering efficacy of atorvastatin in a southern Chinese Han population. Genotypes of three variants in 622...

..., prevention and treatment of stroke are crucial issues in humans. High mobility group box 1 (HMGB1) is non-histone nuclear protein that is currently one of the crucial proinflammatory alarmins in ischemic stroke (IS). It is instantly released from necrotic cells in the ischemic core and activates an early...

...Li-li Zhao; Gang Su; Li-xia Chen; Qi Yan; Xue-ping Wang; Wei Yuan; Lei Wang; Zhen-chang Zhang Ischemic stroke (IS), the leading neurology cause of death and disability worldwide, is influenced by gene polymorphisms. To explore the association between IS and Apolipoprotein E ( APOE ) gene...

... Commons Attribution Licence (CC-BY) ( http://creativecommons.org/licenses/by/3.0/ ) which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. anti-apoptosis anti-oxidative stress Danshensu derivatives ischemic stroke middle...