... contained an ATP-binding pocket, and the ATP molecule was coordinated by eight conserved residues from the N, G1, and G2 boxes. Our study provides novel insight into the histidine kinase BaComP and its homologous proteins. Bacillus amyloliquefaciens Q-426 histidine kinase ComP kinase activity...

... License 4.0 (CC BY) . cryodamage GSK3A kinase activity phosphorylation sperm cryopreservation sperm motility Sperm cryopreservation via liquid nitrogen is a valuable technology for male fertility preservation. It was widely applied in clinical cases such as long-term storage for sperm...

... of the Gly-rich loop, and especially Gly 52 , lowers affinity towards ATP and affects kinase activity [ 17 ] as the γ-phosphate can no longer be efficiently positioned for phosphoryl transfer between the tip of the Gly-rich loop and a basic residue (Lys 168 ) from the so-called ‘catalytic loop’ situated...